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Ischemia modified albumin: a novel biomarker for the detection of cardiac ischemia.
Gaze DC. Gaze DC. Drug Metab Pharmacokinet. 2009;24(4):333-41. doi: 10.2133/dmpk.24.333. Drug Metab Pharmacokinet. 2009. PMID: 19745560 Free article.
Clinical studies indicate that IMA appears to offer on admission an early test which can be combined with electrocardiographic findings and cardiac troponin measurements for the early exclusion of acute coronary syndrome. IMA is an independent predictor of short and long term …
Clinical studies indicate that IMA appears to offer on admission an early test which can be combined with electrocardiographic findings and …
Ischemia-modified albumin predicts short-term outcome and 1-year mortality in patients attending the emergency department for acute ischemic chest pain.
Consuegra-Sanchez L, Bouzas-Mosquera A, Sinha MK, Collinson PO, Gaze DC, Kaski JC. Consuegra-Sanchez L, et al. Among authors: gaze dc. Heart Vessels. 2008 May;23(3):174-80. doi: 10.1007/s00380-007-1031-8. Epub 2008 May 17. Heart Vessels. 2008. PMID: 18484160
A total of 31 (15%) patients experienced the 30-day composite end point and 16 patients (7.7%) died during the 1-year follow-up. Short-term combined end point (9.6% vs 20.4%, P = 0.03) and 1-year mortality rate (11.7% vs 3.8%, log rank 3.978, P = 0.046) were significantly …
A total of 31 (15%) patients experienced the 30-day composite end point and 16 patients (7.7%) died during the 1-year follow-up. Short-te …
Defective endovascular trophoblast invasion in the first trimester is associated with increased maternal serum ischemia-modified albumin.
Papageorghiou AT, Prefumo F, Leslie K, Gaze DC, Collinson PO, Thilaganathan B. Papageorghiou AT, et al. Among authors: gaze dc. Hum Reprod. 2008 Apr;23(4):803-6. doi: 10.1093/humrep/den029. Epub 2008 Feb 16. Hum Reprod. 2008. PMID: 18281685
First trimester maternal serum IMA concentrations in those subsequently developing pre-term pre-eclampsia (n = 19) were compared to randomly chosen controls with normal pregnancy outcome (n = 69). ...
First trimester maternal serum IMA concentrations in those subsequently developing pre-term pre-eclampsia (n = 19) were compared to r …
The role of existing and novel cardiac biomarkers for cardioprotection.
Gaze DC. Gaze DC. Curr Opin Investig Drugs. 2007 Sep;8(9):711-7. Curr Opin Investig Drugs. 2007. PMID: 17729182 Review.
Cardioprotection is an all-encompassing term for physico-biochemical or therapeutic interventions which slow or ameliorate the progression of cardiomyocyte necrosis. ...
Cardioprotection is an all-encompassing term for physico-biochemical or therapeutic interventions which slow or ameliorate the progre …
Impact of repeated prolonged exercise bouts on cardiac function and biomarkers.
Middleton N, Shave R, George K, Whyte G, Simpson R, Florida-James G, Gaze D. Middleton N, et al. Among authors: gaze d. Med Sci Sports Exerc. 2007 Jan;39(1):83-90. doi: 10.1249/01.mss.0000239395.93578.60. Med Sci Sports Exerc. 2007. PMID: 17218888
CONCLUSION: Repeated bouts of prolonged exercise induce short-term reductions in diastolic filling and a cumulative decrease in systolic function, yet these alterations seem to have minimal clinical or functional impact. ...
CONCLUSION: Repeated bouts of prolonged exercise induce short-term reductions in diastolic filling and a cumulative decrease in systo …