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Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity.
Polmear J, Hailes L, Olshansky M, Rischmueller M, L'Estrange-Stranieri E, Fletcher AL, Hibbs ML, Bryant VL, Good-Jacobson KL. Polmear J, et al. Among authors: fletcher al. Clin Transl Immunology. 2023 Oct 4;12(10):e1470. doi: 10.1002/cti2.1470. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37799772 Free PMC article.
OBJECTIVES: B cells drive the production of autoreactive antibody-secreting cells (ASCs) in autoimmune diseases such as Systemic Lupus Erythematosus (SLE) and Sjogren's syndrome, causing long-term organ damage. Current treatments for antibody-mediated autoimmune diseases t …
OBJECTIVES: B cells drive the production of autoreactive antibody-secreting cells (ASCs) in autoimmune diseases such as Systemic Lupus Eryth …
Methods for a population-based Comprehensive Eye care Workload Assessment (CEWA) study in Southern India.
Vardhan A, Rajendran VK, Joseph S, Pooludaiyar L, Datta D, Fletcher AE, Ravilla TD. Vardhan A, et al. Among authors: fletcher ae. Indian J Ophthalmol. 2023 Sep;71(9):3246-3254. doi: 10.4103/IJO.IJO_3228_22. Indian J Ophthalmol. 2023. PMID: 37602616 Free PMC article.
Of the people aged 40 years, 70% underwent FEE. Our study design provides insights for appropriate long-term public health intervention planning, resource allocation, effective service delivery, and designing of eye care services for resource-limited settings....
Of the people aged 40 years, 70% underwent FEE. Our study design provides insights for appropriate long-term public health interventi …
Early Outcomes of Third-Generation Minimally Invasive Chevron-Akin (MICA) Osteotomy for Symptomatic Hallux Valgus Deformity.
Madi NS, Braunstein J, Fletcher AN, Doumat G, Parekh SG. Madi NS, et al. Among authors: fletcher an. Foot Ankle Spec. 2023 May 26:19386400231174814. doi: 10.1177/19386400231174814. Online ahead of print. Foot Ankle Spec. 2023. PMID: 37243379
This technique appears to be effective and safe with no failure of fixation in our patients. We showed in our short-term follow-up, MICA led to significant improvement in pain and radiographic scores.Levels of Evidence: III, retrospective study....
This technique appears to be effective and safe with no failure of fixation in our patients. We showed in our short-term follow-up, M …
Short-Term Outcomes of Jones-Specific Implant Versus Intramedullary Screw and Plate Fixation for Proximal Fifth Metatarsal Fractures.
Chopra A, Anastasio AT, Fletcher AN, Tabarestani TQ, Sharma A, Parekh SG. Chopra A, et al. Among authors: fletcher an. J Foot Ankle Surg. 2023 Sep-Oct;62(5):862-867. doi: 10.1053/j.jfas.2023.05.005. Epub 2023 May 19. J Foot Ankle Surg. 2023. PMID: 37211269
The Jones Specific Implant (JSI) is a novel surgical implant which contours to the native curvature of the fifth metatarsal allowing for a more anatomic fixation. The purpose of this study was to compare short-term complication rates and outcomes of patients treated with t …
The Jones Specific Implant (JSI) is a novel surgical implant which contours to the native curvature of the fifth metatarsal allowing for a m …
Acute changes in myocardial tissue characteristics during hospitalization in patients with COVID-19.
Shanmuganathan M, Kotronias RA, Burrage MK, Ng Y, Banerjee A, Xie C, Fletcher A, Manley P, Borlotti A, Emfietzoglou M, Mentzer AJ, Marin F, Raman B; Oxford Acute Myocardial Infarction (OxAMI) investigators; Tunnicliffe EM, Neubauer S, Piechnik SK, Channon KM, Ferreira VM. Shanmuganathan M, et al. Among authors: fletcher a. Front Cardiovasc Med. 2023 Feb 16;10:1097974. doi: 10.3389/fcvm.2023.1097974. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 36873410 Free PMC article.
Acute COVID-19 appears to induce acute myocardial edema in some patients, which resolves in convalescence, without significant impact on biventricular structure and function in the acute and short-term. Further studies with larger numbers are needed to confirm these findin …
Acute COVID-19 appears to induce acute myocardial edema in some patients, which resolves in convalescence, without significant impact on biv …
Early Outcomes of Combined Total Ankle Total Talus Replacement Using a 3D-Printed Talus Component With Hindfoot Arthrodesis.
Madi NS, Fletcher AN, Pereira GF, Balu A, DeOrio JK, Parekh SG. Madi NS, et al. Among authors: fletcher an. Foot Ankle Spec. 2023 Jun;16(3):273-282. doi: 10.1177/19386400221120567. Epub 2022 Aug 29. Foot Ankle Spec. 2023. PMID: 36039497
A combined total ankle and total talus replacement (TATTR) with hindfoot arthrodesis may be utilized for end-stage talar AVN with tibiotalar and hindfoot joint arthritis. The purpose of this study is to evaluate the short-term outcomes of combined TATTR with hindfoot arthr …
A combined total ankle and total talus replacement (TATTR) with hindfoot arthrodesis may be utilized for end-stage talar AVN with tibiotalar …
Outcomes following total talus replacement: A systematic review.
Johnson LG, Anastasio AT, Fletcher AN, Hendren S, Adams SB. Johnson LG, et al. Among authors: fletcher an. Foot Ankle Surg. 2022 Dec;28(8):1194-1201. doi: 10.1016/j.fas.2022.08.010. Epub 2022 Aug 20. Foot Ankle Surg. 2022. PMID: 36028440 Review.
CONCLUSION: TTR is an alternative to joint sacrificing procedures to maintain range of motion through the tibiotalar joint and allow for maintenance of normal foot and ankle biomechanics. Despite promising early- and mid-term outcomes, future, prospective, randomized resea …
CONCLUSION: TTR is an alternative to joint sacrificing procedures to maintain range of motion through the tibiotalar joint and allow for mai …
Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study.
Fotopoulou C, Khan T, Bracinik J, Glasbey J, Abu-Rustum N, Chiva L, Fagotti A, Fujiwara K, Ghebre R, Gutelkin M, Konney TO, Ng J, Pareja R, Kottayasamy Seenivasagam R, Sehouli J, Surappa STS, Bhangu A, Leung E, Sundar S; CovidSurg Gynecological Cancer Collaborators. Fotopoulou C, et al. Am J Obstet Gynecol. 2022 Nov;227(5):735.e1-735.e25. doi: 10.1016/j.ajog.2022.06.052. Epub 2022 Jun 30. Am J Obstet Gynecol. 2022. PMID: 35779589 Free PMC article.
OBJECTIVE: This study aimed to evaluate the changes in care and short-term outcomes of surgical patients with gynecologic cancers during the COVID-19 pandemic. ...
OBJECTIVE: This study aimed to evaluate the changes in care and short-term outcomes of surgical patients with gynecologic cancers dur …
Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.
COVIDSurg Collaborative. COVIDSurg Collaborative. Lancet Oncol. 2021 Nov;22(11):1507-1517. doi: 10.1016/S1470-2045(21)00493-9. Epub 2021 Oct 5. Lancet Oncol. 2021. PMID: 34624250 Free PMC article. Clinical Trial.
INTERPRETATION: Cancer surgery systems worldwide were fragile to lockdowns, with one in seven patients who were in regions with full lockdowns not undergoing planned surgery and experiencing longer preoperative delays. Although short-term oncological outcomes were not comp …
INTERPRETATION: Cancer surgery systems worldwide were fragile to lockdowns, with one in seven patients who were in regions with full lockdow …
Endoscopic Proximal Hamstring Repair Is Safe and Efficacious With High Patient Satisfaction at a Minimum of 2-Year Follow-Up.
Fletcher AN, Pereira GF, Lau BC, Mather RC 3rd. Fletcher AN, et al. Arthroscopy. 2021 Nov;37(11):3275-3285. doi: 10.1016/j.arthro.2021.03.067. Epub 2021 Apr 19. Arthroscopy. 2021. PMID: 33887414
PURPOSE: To evaluate the short-term outcomes of endoscopic proximal hamstring repair including clinical outcomes, patient-reported outcomes, and complications. ...There was a 90.0% (n=27) satisfaction rate. CONCLUSIONS: Short-term follow-up for endoscopic proximal h …
PURPOSE: To evaluate the short-term outcomes of endoscopic proximal hamstring repair including clinical outcomes, patient-reported ou …
94 results