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Reversible and irreversible differentiation of cardiac fibroblasts.
Driesen RB, Nagaraju CK, Abi-Char J, Coenen T, Lijnen PJ, Fagard RH, Sipido KR, Petrov VV. Driesen RB, et al. Among authors: fagard rh. Cardiovasc Res. 2014 Mar 1;101(3):411-22. doi: 10.1093/cvr/cvt338. Epub 2013 Dec 23. Cardiovasc Res. 2014. PMID: 24368833 Free PMC article.
Stress fibre de-polymerization could also be induced by mechanical strain release in p-MyoFb and non-p-MyoFb (2-day cultures in unrestrained 3-D collagen matrices). Only p-MyoFb showed true dedifferentiation after long-term 3-D cultures. CONCLUSIONS: Fb, p-MyoFb, and non-p …
Stress fibre de-polymerization could also be induced by mechanical strain release in p-MyoFb and non-p-MyoFb (2-day cultures in unrestrained …
Heart rate variability after heart transplantation: a 10-year longitudinal follow-up study.
Cornelissen VA, Vanhaecke J, Aubert AE, Fagard RH. Cornelissen VA, et al. Among authors: fagard rh. J Cardiol. 2012 Mar;59(2):220-4. doi: 10.1016/j.jjcc.2011.12.002. Epub 2012 Jan 21. J Cardiol. 2012. PMID: 22266458 Free article.
Our aim was to test this hypothesis by examining HRV in long-term longitudinal follow-up study of HTx recipients. METHODS AND RESULTS: 14 HTx recipients (11 men) were studied 1-48 (median 13) months (baseline) and 119-172 (median 141) months after HTx (follow-up). ...This …
Our aim was to test this hypothesis by examining HRV in long-term longitudinal follow-up study of HTx recipients. METHODS AND RESULTS …
Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population.
Kuznetsova T, Citterio L, Herbots L, Carpini SD, Thijs L, Casamassima N, Richart T, Fagard RH, Bianchi G, Staessen JA. Kuznetsova T, et al. Among authors: fagard rh. J Hypertens. 2008 Jun;26(6):1229-36. doi: 10.1097/HJH.0b013e3282f97dcd. J Hypertens. 2008. PMID: 18475162 Free article.
The best fitting model for lateral Ea and Ea/Aa included ADD1, ADD3, and the three-way interaction term of both genes with age. Below the age of 50 years, the lateral Ea/Aa ratio was higher in ADD1 Trp allele carriers than in GlyGly homozygotes (1.91 vs. 1.73; P = 0.006), …
The best fitting model for lateral Ea and Ea/Aa included ADD1, ADD3, and the three-way interaction term of both genes with age. Below …
White-coat hypertension: a clinical review.
Celis H, Fagard RH. Celis H, et al. Among authors: fagard rh. Eur J Intern Med. 2004 Oct;15(6):348-357. doi: 10.1016/j.ejim.2004.08.001. Eur J Intern Med. 2004. PMID: 15522568
The value of other possible determinants such as (non) smoking status, duration of hypertension, left ventricular mass, number of OBP measurements, educational level, etc. is less consistently shown. Although, for various reasons, studies evaluating the long-term effects o …
The value of other possible determinants such as (non) smoking status, duration of hypertension, left ventricular mass, number of OBP measur …
Blood pressure, serum total cholesterol and contraceptive pill use in 17-year-old girls.
Nawrot TS, Den Hond E, Fagard RH, Hoppenbrouwers K, Staessen JA. Nawrot TS, et al. Among authors: fagard rh. Eur J Cardiovasc Prev Rehabil. 2003 Dec;10(6):438-42. doi: 10.1097/01.hjr.0000103463.31435.1e. Eur J Cardiovasc Prev Rehabil. 2003. PMID: 14671466
CONCLUSIONS: In 17-year-old girls, the use of oral contraceptives was associated with a nearly 5 mmHg higher systolic blood pressure and a 0.4 mmol/l higher level of serum total cholesterol. The long-term prognostic implications of our findings remain to be elucidated....
CONCLUSIONS: In 17-year-old girls, the use of oral contraceptives was associated with a nearly 5 mmHg higher systolic blood pressure and a 0 …
How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2).
Thijs L, Staessen JA, Beleva S, Birkenhäger WH, Bulpitt CJ, Celis H, Fletcher AE, Kermova R, Leonetti G, Laks T, Mantov S, Nachev C, Sarti C, Tuomilehto J, Fagard RH; On behalf of the Systolic Hypertension in Europe Investigators. Thijs L, et al. Among authors: fagard rh. Curr Control Trials Cardiovasc Med. 2001 Oct 18;2(6):298-306. doi: 10.1186/cvm-2-6-298. Curr Control Trials Cardiovasc Med. 2001. PMID: 11806817 Free PMC article.
BACKGROUND: The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy starting with nitrendipine reduces the risk of cardiovascular complications in elderly patients with isolated systolic …
BACKGROUND: The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure ( …
T-lymphocyte and plasma angiotensin-converting enzyme activity during enalapril and losartan administration in humans.
Petrov VV, Fagard RH, Lijnen PJ. Petrov VV, et al. Among authors: fagard rh. J Cardiovasc Pharmacol. 2001 Oct;38(4):578-83. doi: 10.1097/00005344-200110000-00010. J Cardiovasc Pharmacol. 2001. PMID: 11588528 Clinical Trial.
This study evaluated the long-term effects of the angiotensin-converting enzyme inhibitor enalapril and the angiotensin II type 1 receptor antagonist losartan on the angiotensin-converting enzyme activity in T lymphocytes and plasma in patients with essential hypertension. …
This study evaluated the long-term effects of the angiotensin-converting enzyme inhibitor enalapril and the angiotensin II type 1 rec …
Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trial.
Celis H, Thijs L, Staessen JA, Birkenhäger WH, Bulpitt CJ, de Leeuw PW, Leonetti G, Nachev C, Tuomilehto J, Fagard RH; Syst-Eur Investigators. Celis H, et al. Among authors: fagard rh. J Hum Hypertens. 2001 Sep;15(9):613-8. doi: 10.1038/sj.jhh.1001235. J Hum Hypertens. 2001. PMID: 11550107 Free article. Clinical Trial.
Although there was no significant interaction between calcium-channel blocker (CCB)-based treatment and chronic NSAID intake for any of the end points, chronic NSAID intake tended to be associated with a lower incidence of bleeding on active treatment as compared to placebo (P-va …
Although there was no significant interaction between calcium-channel blocker (CCB)-based treatment and chronic NSAID intake for any of the …
Long-term treatment with enalapril or losartan does not show antiproliferative effects in peripheral blood mononuclear cells.
Petrov VV, Fagard RH, Lijnen PJ. Petrov VV, et al. Among authors: fagard rh. Methods Find Exp Clin Pharmacol. 2001 Apr;23(3):149-52. doi: 10.1358/mf.2001.23.3.627949. Methods Find Exp Clin Pharmacol. 2001. PMID: 11523315 Free article. Clinical Trial.
The objective of this study was to evaluate the long-term effects of enalapril, an angiotensin-converting enzyme inhibitor, and losartan, an angiotensin type 1 receptor antagonist, on the proliferation of peripheral blood mononuclear cells (PBMC) in patients with essential …
The objective of this study was to evaluate the long-term effects of enalapril, an angiotensin-converting enzyme inhibitor, and losar …
A population-based study on the determinants of heart rate and heart rate variability in the frequency domain.
Fagard RH. Fagard RH. Verh K Acad Geneeskd Belg. 2001;63(1):57-89; discussion 90-1. Verh K Acad Geneeskd Belg. 2001. PMID: 11284389 Review.
The main objective of the present study was to identify the determinants of heart rate (HR) and of the low-frequency (LF) and high-frequency (HF) components of short-term heart rate variability (HRV) in the population. HF power represents vagal modulation of HRV and LF pow …
The main objective of the present study was to identify the determinants of heart rate (HR) and of the low-frequency (LF) and high-frequency …
15 results