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Association between GDF15, poverty and mortality in urban middle-aged African American and white adults.
Freeman DW, Noren Hooten N, Kim Y, Mode NA, Ejiogu N, Zonderman AB, Evans MK. Freeman DW, et al. Among authors: evans mk. PLoS One. 2020 Aug 7;15(8):e0237059. doi: 10.1371/journal.pone.0237059. eCollection 2020. PLoS One. 2020. PMID: 32764826 Free PMC article.
There was an interaction between logGDF15 and poverty status on all-cause mortality (p<0.05). The GDF15poverty status interaction term improved model calibration for all-cause mortality. Our study provides the first evidence that the effect of elevated GDF15 on all-caus …
There was an interaction between logGDF15 and poverty status on all-cause mortality (p<0.05). The GDF15poverty status interaction term …
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de Las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR, Guo X, Manning A, Chasman DI, Aschard H, Bartz TM, Bielak LF, Campbell A, Cheng CY, Dorajoo R, Hartwig FP, Horimoto ARVR, Li C, Li-Gao R, Liu Y, Marten J, Musani SK, Ntalla I, Rankinen T, Richard M, Sim X, Smith AV, Tajuddin SM, Tayo BO, Vojinovic D, Warren HR, Xuan D, Alver M, Boissel M, Chai JF, Chen X, Christensen K, Divers J, Evangelou E, Gao C, Girotto G, Harris SE, He M, Hsu FC, Kühnel B, Laguzzi F, Li X, Lyytikäinen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Rueedi R, Shu XO, Snieder H, Sofer T, Takeuchi F, Verweij N, Ware EB, Weiss S, Yanek LR, Amin N, Arking DE, Arnett DK, Bergmann S, Boerwinkle E, Brody JA, Broeckel U, Brumat M, Burke G, Cabrera CP, Canouil M, Chee ML, Chen YI, Cocca M, Connell J, de Silva HJ, de Vries PS, Eiriksdottir G, Faul JD, Fisher V, Forrester T, Fox EF, Friedlander Y, Gao H, Gigante B, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt S, Ikram MA, Irvin MR, Kähönen M, Kavousi M, Khor CC, Kilpeläinen TO, Koh WP, Komulainen P, Kraja AT, Krieger JE, Langefeld CD, Li Y, Liang J, Liewald DCM, Liu CT, Liu J, Lohman KK, Mägi R, McKenzie … See abstract for full author list ➔ de Las Fuentes L, et al. Among authors: evans mk. Mol Psychiatry. 2021 Jun;26(6):2111-2125. doi: 10.1038/s41380-020-0719-3. Epub 2020 May 5. Mol Psychiatry. 2021. PMID: 32372009 Free PMC article.
Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction effects. Analyses were performed for systolic BP, diastolic BP, mean arterial pressure, and pulse pressure. ...
Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction ef …
Techniques to Induce and Quantify Cellular Senescence.
Noren Hooten N, Evans MK. Noren Hooten N, et al. Among authors: evans mk. J Vis Exp. 2017 May 1;(123):55533. doi: 10.3791/55533. J Vis Exp. 2017. PMID: 28518126 Free PMC article.
In response to cellular stress or damage, proliferating cells can induce a specific program that initiates a state of long-term cell-cycle arrest, termed cellular senescence. Accumulation of senescent cells occurs with organismal aging and through continual culturing in vi …
In response to cellular stress or damage, proliferating cells can induce a specific program that initiates a state of long-term cell- …
Race, Neighborhood Economic Status, Income Inequality and Mortality.
Mode NA, Evans MK, Zonderman AB. Mode NA, et al. Among authors: evans mk. PLoS One. 2016 May 12;11(5):e0154535. doi: 10.1371/journal.pone.0154535. eCollection 2016. PLoS One. 2016. PMID: 27171406 Free PMC article.
The significant association of neighborhood economic status and income inequality with mortality beyond the synergistic combination of sex, race and individual poverty status suggests the long-term importance of small area influence on overall mortality....
The significant association of neighborhood economic status and income inequality with mortality beyond the synergistic combination of sex, …
Enhanced sensitivity and long-term G2 arrest in hydrogen peroxide-treated Ku80-null cells are unrelated to DNA repair defects.
Arrington ED, Caldwell MC, Kumaravel TS, Lohani A, Joshi A, Evans MK, Chen HT, Nussenzweig A, Holbrook NJ, Gorospe M. Arrington ED, et al. Among authors: evans mk. Free Radic Biol Med. 2000 Dec;29(11):1166-76. doi: 10.1016/s0891-5849(00)00439-1. Free Radic Biol Med. 2000. PMID: 11121725
Here, treatment of embryo fibroblasts (MEFs) derived from either wild-type or Ku80-null (Ku80(-/-)) mice with various stress agents revealed that hydrogen peroxide (H(2)O(2)) was markedly more cytotoxic for Ku80(-/-) MEFs and led to their long-term accumulation in the G2 p …
Here, treatment of embryo fibroblasts (MEFs) derived from either wild-type or Ku80-null (Ku80(-/-)) mice with various stress agents revealed …
Immunoglobulin A subclasses in infants' saliva and in saliva and milk from their mothers.
Fitzsimmons SP, Evans MK, Pearce CL, Sheridan MJ, Wientzen R, Cole MF. Fitzsimmons SP, et al. Among authors: evans mk. J Pediatr. 1994 Apr;124(4):566-73. doi: 10.1016/s0022-3476(05)83135-x. J Pediatr. 1994. PMID: 8151471
Secretory IgA and subclasses 1 and 2 concentrations were determined in saliva from 40 healthy, term infants from birth to age 18 months, and in parallel milk samples from the infants' mothers who were breast-feeding during the first 6 months after birth. ...T …
Secretory IgA and subclasses 1 and 2 concentrations were determined in saliva from 40 healthy, term infants from birth to age …