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1986 1
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2020 3
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2022 2
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Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial.
PD Med Collaborative Group; Gray R, Ives N, Rick C, Patel S, Gray A, Jenkinson C, McIntosh E, Wheatley K, Williams A, Clarke CE. PD Med Collaborative Group, et al. Lancet. 2014 Sep 27;384(9949):1196-205. doi: 10.1016/S0140-6736(14)60683-8. Epub 2014 Jun 11. Lancet. 2014. PMID: 24928805 Clinical Trial.
We aimed to establish which of these three classes of drug, as initial treatment, provides the most effective long-term control of symptoms and best quality of life for people with early Parkinson's disease. ...
We aimed to establish which of these three classes of drug, as initial treatment, provides the most effective long-term control of sy …
Long-term Effectiveness of Adjuvant Treatment With Catechol-O-Methyltransferase or Monoamine Oxidase B Inhibitors Compared With Dopamine Agonists Among Patients With Parkinson Disease Uncontrolled by Levodopa Therapy: The PD MED Randomized Clinical Trial.
Gray R, Patel S, Ives N, Rick C, Woolley R, Muzerengi S, Gray A, Jenkinson C, McIntosh E, Wheatley K, Williams A, Clarke CE; PD MED Collaborative Group. Gray R, et al. JAMA Neurol. 2022 Feb 1;79(2):131-140. doi: 10.1001/jamaneurol.2021.4736. JAMA Neurol. 2022. PMID: 34962574 Free PMC article. Clinical Trial.
Among these patients, it is uncertain which drug class is more effective as adjuvant therapy. OBJECTIVE: To compare the long-term effects on patient-rated quality of life of adding a dopamine agonist vs a dopamine reuptake inhibitor (DRI), either a monoamine oxidase type B …
Among these patients, it is uncertain which drug class is more effective as adjuvant therapy. OBJECTIVE: To compare the long-term eff …
Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial: An intention-to-treat analysis of amputation-free and overall survival in patients randomized to a bypass surgery-first or a balloon angioplasty-first revascularization strategy.
Bradbury AW, Adam DJ, Bell J, Forbes JF, Fowkes FG, Gillespie I, Ruckley CV, Raab GM; BASIL trial Participants. Bradbury AW, et al. J Vasc Surg. 2010 May;51(5 Suppl):5S-17S. doi: 10.1016/j.jvs.2010.01.073. J Vasc Surg. 2010. PMID: 20435258 Free article. Clinical Trial.
BACKGROUND: A 2005 interim analysis of the Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial showed that in patients with severe lower limb ischemia (SLI; rest pain, ulceration, gangrene) due to infrainguinal disease, bypass surgery (BSX)-first and balloon an …
BACKGROUND: A 2005 interim analysis of the Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial showed that in patients wi …
Ethics and Policy for Bioprinting.
Goddard E, Dodds S. Goddard E, et al. Among authors: dodds s. Methods Mol Biol. 2020;2140:43-64. doi: 10.1007/978-1-0716-0520-2_4. Methods Mol Biol. 2020. PMID: 32207105
The inclusion of living cells and biomaterials in the 3D printing process raises ethical, policy, and regulatory issues at each stage of the bioprinting process that include the source of cells and materials, stability and biocompatibility of cells and materials, disposal of 3D-p …
The inclusion of living cells and biomaterials in the 3D printing process raises ethical, policy, and regulatory issues at each stage of the …
Association of Patient-Level and Hospital-Level Factors With Timely Fracture Care by Race.
Gitajn IL, Werth P, Fernandes E, Sprague S, O'Hara NN, Bzovsky S, Marchand LS, Patterson JT, Lee C, Slobogean GP; PREP-IT Investigators. Gitajn IL, et al. JAMA Netw Open. 2022 Nov 1;5(11):e2244357. doi: 10.1001/jamanetworkopen.2022.44357. JAMA Netw Open. 2022. PMID: 36449289 Free PMC article.
After controlling for patient-level characteristics, there was an independent association between missing the 24-hour benchmark and hospital population insurance coverage (OR, 0.94; 95% CI, 0.89-0.98; P = .005) and the interaction term between hospital population insurance …
After controlling for patient-level characteristics, there was an independent association between missing the 24-hour benchmark and hospital …
Adaptations to chronic rapamycin in mice.
Dodds SG, Livi CB, Parihar M, Hsu HK, Benavides AD, Morris J, Javors M, Strong R, Christy B, Hasty P, Sharp ZD. Dodds SG, et al. Pathobiol Aging Age Relat Dis. 2016 May 27;6:31688. doi: 10.3402/pba.v6.31688. eCollection 2016. Pathobiol Aging Age Relat Dis. 2016. PMID: 27237224 Free PMC article.
Chronic treatment with encapsulated rapamycin (eRapa) extended health and life span for wild-type and cancer-prone mice. Yet, the long-term consequences of chronic eRapa treatment are not known at the organ level. ...
Chronic treatment with encapsulated rapamycin (eRapa) extended health and life span for wild-type and cancer-prone mice. Yet, the long-te …
Lower limb acute compartment syndrome after colorectal surgery in prolonged lithotomy position.
Beraldo S, Dodds SR. Beraldo S, et al. Among authors: dodds sr. Dis Colon Rectum. 2006 Nov;49(11):1772-80. doi: 10.1007/s10350-006-0712-1. Dis Colon Rectum. 2006. PMID: 17036205 Review.
PURPOSE: Acute compartment syndrome in patients undergoing prolonged colorectal procedures is uncommon but can have catastrophic consequences for the patient with the development of metabolic acidosis, myoglobinuric renal failure, Volkmann's contracture, limb loss, and death. The …
PURPOSE: Acute compartment syndrome in patients undergoing prolonged colorectal procedures is uncommon but can have catastrophic consequence …
Nurse-led arterial blood gas sampling for patients.
Dodds S, Williamson G. Dodds S, et al. Nurs Times. 2007 Feb 20-26;103(8):44-5. Nurs Times. 2007. PMID: 17333877
Following the introduction of new guidelines in February 2006, assessments for long-term oxygen therapy are now being undertaken by respiratory nurse specialists. ...
Following the introduction of new guidelines in February 2006, assessments for long-term oxygen therapy are now being undertaken by r …
Mortality and morbidity in obstructive sleep apnoea-hypopnoea syndrome: results from a 30-year prospective cohort study.
Dodds S, Williams LJ, Roguski A, Vennelle M, Douglas NJ, Kotoulas SC, Riha RL. Dodds S, et al. ERJ Open Res. 2020 Sep 14;6(3):00057-2020. doi: 10.1183/23120541.00057-2020. eCollection 2020 Jul. ERJ Open Res. 2020. PMID: 32963994 Free PMC article.
Patients were followed up for an average of 14.83.7 years. RESULTS: Imputation analysis showed that long-term CPAP users (>5 years) were 5.63 times more likely to be alive at study end than non-CPAP users (95% CI: 4.83-6.58, p<0.001) and 1.74-times more likely than s …
Patients were followed up for an average of 14.83.7 years. RESULTS: Imputation analysis showed that long-term CPAP users (>5 years …
Real-World Gluten Exposure in Patients With Celiac Disease on Gluten-Free Diets, Determined From Gliadin Immunogenic Peptides in Urine and Fecal Samples.
Stefanolo JP, Tálamo M, Dodds S, de la Paz Temprano M, Costa AF, Moreno ML, Pinto-Sánchez MI, Smecuol E, Vázquez H, Gonzalez A, Niveloni SI, Mauriño E, Verdu EF, Bai JC. Stefanolo JP, et al. Among authors: dodds s. Clin Gastroenterol Hepatol. 2021 Mar;19(3):484-491.e1. doi: 10.1016/j.cgh.2020.03.038. Epub 2020 Mar 23. Clin Gastroenterol Hepatol. 2021. PMID: 32217152
We studied levels of gluten immunogenic peptides (GIP) in fecal and urine samples, collected over 4 weeks, from patients with celiac disease on a long-term GFD. METHODS: We performed a prospective study of 53 adults with celiac disease who had been on a GFD for more than 2 …
We studied levels of gluten immunogenic peptides (GIP) in fecal and urine samples, collected over 4 weeks, from patients with celiac disease …
19 results