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Long-term intensive endurance exercise training is associated to reduced markers of cellular senescence in the colon mucosa of older adults.
Demaria M, Bertozzi B, Veronese N, Spelta F, Cava E, Tosti V, Piccio L, Early DS, Fontana L. Demaria M, et al. NPJ Aging. 2023 Feb 27;9(1):3. doi: 10.1038/s41514-023-00100-w. NPJ Aging. 2023. PMID: 36849522 Free PMC article.
Senescent cells accumulate over time and promote a variety of age-related pathologies from neurodegenerative disorders to cancer. Whether long-term intensive exercise training affect the accumulation of age-associated cellular senescence is still unclear. ...
Senescent cells accumulate over time and promote a variety of age-related pathologies from neurodegenerative disorders to cancer. Whether lo …
Prognostic implications of cellular senescence in resected non-small cell lung cancer.
Domen A, Deben C, De Pauw I, Hermans C, Lambrechts H, Verswyvel J, Siozopoulou V, Pauwels P, Demaria M, van de Wiel M, Janssens A, Hendriks JMH, Van Schil P, Vermorken JB, Vandamme T, Prenen H, Peeters M, Lardon F, Wouters A. Domen A, et al. Among authors: demaria m. Transl Lung Cancer Res. 2022 Aug;11(8):1526-1539. doi: 10.21037/tlcr-22-192. Transl Lung Cancer Res. 2022. PMID: 36090630 Free PMC article.
BACKGROUND: Cure and long-term survival for non-small cell lung cancer (NSCLC) remains hard to achieve. ...
BACKGROUND: Cure and long-term survival for non-small cell lung cancer (NSCLC) remains hard to achieve. ...
Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial.
Senore C, Riggi E, Armaroli P, Bonelli L, Sciallero S, Zappa M, Arrigoni A, Casella C, Crosta C, Falcini F, Ferrero F, Fracchia M, Giuliani O, Risio M, Russo AG, Visioli CB, Rosso S, Segnan N; SCORE Working Group. Senore C, et al. Ann Intern Med. 2022 Jan;175(1):36-45. doi: 10.7326/M21-0977. Epub 2021 Nov 9. Ann Intern Med. 2022. PMID: 34748376 Clinical Trial.
BACKGROUND: Recent reports showed that the protective effect of flexible sigmoidoscopy (FS) screening was maintained up to17 years, although differences were reported by sex. OBJECTIVE: To assess long-term reduction of colorectal cancer (CRC) incidence and mortality after …
BACKGROUND: Recent reports showed that the protective effect of flexible sigmoidoscopy (FS) screening was maintained up to17 years, although …
Short-term effects on emergency room access or hospital admissions for cardio-respiratory diseases: methodology and results after three years of functioning of a waste-to-energy incinerator in Turin (Italy).
Gandini M, Farina E, Demaria M, Lorusso B, Crosetto L, Rowinski M, Ivaldi C, Cadum E, Bena A. Gandini M, et al. Among authors: demaria m. Int J Environ Health Res. 2022 May;32(5):1164-1174. doi: 10.1080/09603123.2020.1849579. Epub 2020 Nov 29. Int J Environ Health Res. 2022. PMID: 33249915
Cellular senescence as a potential mediator of COVID-19 severity in the elderly.
Nehme J, Borghesan M, Mackedenski S, Bird TG, Demaria M. Nehme J, et al. Among authors: demaria m. Aging Cell. 2020 Oct;19(10):e13237. doi: 10.1111/acel.13237. Epub 2020 Sep 21. Aging Cell. 2020. PMID: 32955770 Free PMC article. Review.
Identifying a functional association between SARS-CoV-2 infection and the process of biological aging may provide a tractable avenue for therapy to prevent acute and long-term disease. Here, we discuss how cellular senescence-a state of stable growth arrest characterized b …
Identifying a functional association between SARS-CoV-2 infection and the process of biological aging may provide a tractable avenue for the …
The expression of calpain-1 and androgen receptor in breast cancer and their correlation with clinicopathological characteristics: An immunohistochemical retrospective study.
Rajković-Molek K, Mustać E, Avirović M, Georgev P, Demaria M, Aničić J, Ban J, Babarović E. Rajković-Molek K, et al. Among authors: demaria m. Pathol Res Pract. 2020 Sep;216(9):153068. doi: 10.1016/j.prp.2020.153068. Epub 2020 Jun 20. Pathol Res Pract. 2020. PMID: 32825941
In this study we enrolled 219 breast cancer patients with long term follow-up information available. Immunohistochemical methods on a tissue microarray were used to investigate expression of calpain-1 and AR in tumor cells. ...
In this study we enrolled 219 breast cancer patients with long term follow-up information available. Immunohistochemical methods on a …
An Italian Network of Population-Based Birth Cohorts to Evaluate Social and Environmental Risk Factors on Pregnancy Outcomes: The LEAP Study.
Spadea T, Pacelli B, Ranzi A, Galassi C, Rusciani R, Demaria M, Caranci N, Michelozzi P, Cerza F, Davoli M, Forastiere F, Cesaroni G. Spadea T, et al. Among authors: demaria m. Int J Environ Res Public Health. 2020 May 21;17(10):3614. doi: 10.3390/ijerph17103614. Int J Environ Res Public Health. 2020. PMID: 32455694 Free PMC article.
In Italy, few multicentre population-based studies on pregnancy outcomes are available. Therefore, we established a network of population-based birth cohorts in the cities of Turin, Reggio Emilia, Modena, Bologna, and Rome (northern and central Italy), to study the role of …
In Italy, few multicentre population-based studies on pregnancy outcomes are available. Therefore, we established a network of population-ba …
[SENTIERI: Epidemiological Study of Residents in National Priority Contaminated Sites. Fifth Report].
Zona A, Iavarone I, Buzzoni C, Conti S, Santoro M, Fazzo L, Pasetto R, Pirastu R, Bruno C, Ancona C, Bianchi F, Forastiere F, Manno V, Minelli G, Minerba A, Minichilli F, Stoppa G, Pierini A, Ricci P, Scondotto S, Bisceglia L, Cernigliaro A, Ranzi A, Comba P; Gruppo di lavoro SENTIERI; Gruppo di lavoro AIRTUM-SENTIERI; Gruppo di lavoro Malformazioni congenite-SENTIERI. Zona A, et al. Epidemiol Prev. 2019 Mar-Jun;43(2-3 Suppl 1):1-208. doi: 10.19191/EP19.2-3.S1.032. Epidemiol Prev. 2019. PMID: 31295974 Free article. Italian.
In seven out of 15 NPCSs, an excess prevalence rate of overall congenital anomalies at birth was observed. Congenital anomalies excesses included the following sites: genital organs, heart, limbs, nervous system, digestive system, and urinary system. ...There is not a unif …
In seven out of 15 NPCSs, an excess prevalence rate of overall congenital anomalies at birth was observed. Congenital anomalies exces …
LIFE Med Hiss: An innovative cohort design for public health.
Gandini M, Scarinzi C, Bande S, Berti G, Ciancarella L, Costa G, Demaria M, Ghigo S, Marinacci C, Piersanti A, Sebastiani G, Cadum E. Gandini M, et al. Among authors: demaria m. MethodsX. 2018 Dec 18;6:82-91. doi: 10.1016/j.mex.2018.12.007. eCollection 2019. MethodsX. 2018. PMID: 30627518 Free PMC article.
The aim of MED HISS methodology was to test the effectiveness of a low-cost approach to study long-term effects of air pollution, applicable in all European countries. ...
The aim of MED HISS methodology was to test the effectiveness of a low-cost approach to study long-term effects of air pollution, app …
Long term effect of air pollution on incident hospital admissions: Results from the Italian Longitudinal Study within LIFE MED HISS project.
Gandini M, Scarinzi C, Bande S, Berti G, Carnà P, Ciancarella L, Costa G, Demaria M, Ghigo S, Piersanti A, Rowinski M, Spadea T, Stroscia M, Cadum E; LIFE MEDHISS collaborative Group. Gandini M, et al. Among authors: demaria m. Environ Int. 2018 Dec;121(Pt 2):1087-1097. doi: 10.1016/j.envint.2018.10.020. Epub 2018 Oct 23. Environ Int. 2018. PMID: 30366659 Free article.
Few studies assessed the long term effect of air pollution on hospital admissions in European cohorts. OBJECTIVE: The objective of this paper is to estimate the long term effect of fine particulate matter (PM2.5) and nitrogen dioxide (NO(2)) on first-ever (incident) …
Few studies assessed the long term effect of air pollution on hospital admissions in European cohorts. OBJECTIVE: The objective of th …
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