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Military Genitourinary Trauma: Policies, Implications, and Ethics.
Dean WK, Caplan AL, Parent B. Dean WK, et al. Hastings Cent Rep. 2016 Nov;46(6):10-13. doi: 10.1002/hast.643. Hastings Cent Rep. 2016. PMID: 27875650
But as policy changes move the conversation into the open, we must be fully aware of the far-reaching and long-term impacts of decisions on those who have sustained genitourinary injury. ...
But as policy changes move the conversation into the open, we must be fully aware of the far-reaching and long-term impacts of decisi …
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells.
Seisenberger S, Andrews S, Krueger F, Arand J, Walter J, Santos F, Popp C, Thienpont B, Dean W, Reik W. Seisenberger S, et al. Among authors: dean w. Mol Cell. 2012 Dec 28;48(6):849-62. doi: 10.1016/j.molcel.2012.11.001. Epub 2012 Dec 6. Mol Cell. 2012. PMID: 23219530 Free PMC article.
Global loss of methylation takes place during PGC expansion and migration with evidence for passive demethylation, but sequences that carry long-term epigenetic memory (imprints, CpG islands on the X chromosome, germline-specific genes) only become demethylated upon entry …
Global loss of methylation takes place during PGC expansion and migration with evidence for passive demethylation, but sequences that carry …
Regulation of placental efficiency for nutrient transport by imprinted genes.
Angiolini E, Fowden A, Coan P, Sandovici I, Smith P, Dean W, Burton G, Tycko B, Reik W, Sibley C, Constância M. Angiolini E, et al. Among authors: dean w. Placenta. 2006 Apr;27 Suppl A:S98-102. doi: 10.1016/j.placenta.2005.12.008. Epub 2006 Feb 28. Placenta. 2006. PMID: 16503350 Review.
Intrauterine growth and development can impact upon the long-term health of an individual. The fetus is dependent upon the placenta for its supply of nutrients and oxygen from the mother. ...
Intrauterine growth and development can impact upon the long-term health of an individual. The fetus is dependent upon the placenta f …
Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems.
Constância M, Angiolini E, Sandovici I, Smith P, Smith R, Kelsey G, Dean W, Ferguson-Smith A, Sibley CP, Reik W, Fowden A. Constância M, et al. Among authors: dean w. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19219-24. doi: 10.1073/pnas.0504468103. Epub 2005 Dec 19. Proc Natl Acad Sci U S A. 2005. PMID: 16365304 Free PMC article.
An altered balance between supply and demand can lead to deviations from this trajectory with long-term consequences for health. We have previously shown that in a knockout lacking the imprinted placental-specific Igf2 transcript (P0), growth of the placenta is compromised …
An altered balance between supply and demand can lead to deviations from this trajectory with long-term consequences for health. We h …
Generation of monoparental embryos for investigation into genomic imprinting.
Dean WL, Kelsey G, Reik W. Dean WL, et al. Methods Mol Biol. 2001;181:1-19. doi: 10.1385/1-59259-211-2:1. Methods Mol Biol. 2001. PMID: 12843438
The seminal work of McGrath and Solter (1) and independently of Surani et al. (2) in 1984 established the fundamental principle of nuclear nonequivalency; that is, chromosomes of both paternal and maternal origin are required for development to term in mammals. This was ac …
The seminal work of McGrath and Solter (1) and independently of Surani et al. (2) in 1984 established the fundamental principle of nuclear n …
Regulation of supply and demand for maternal nutrients in mammals by imprinted genes.
Reik W, Constância M, Fowden A, Anderson N, Dean W, Ferguson-Smith A, Tycko B, Sibley C. Reik W, et al. Among authors: dean w. J Physiol. 2003 Feb 15;547(Pt 1):35-44. doi: 10.1113/jphysiol.2002.033274. Epub 2003 Jan 24. J Physiol. 2003. PMID: 12562908 Free PMC article. Review.
These data and hypotheses are important, as deregulation of supply and demand affects fetal growth and has long term consequences for health in mammals both in the neonatal period and, as a result of fetal programming, in adulthood....
These data and hypotheses are important, as deregulation of supply and demand affects fetal growth and has long term consequences for …
Community mental health care for women with severe mental illness who are parents.
Brunette MF, Dean W. Brunette MF, et al. Among authors: dean w. Community Ment Health J. 2002 Apr;38(2):153-65. doi: 10.1023/a:1014599222218. Community Ment Health J. 2002. PMID: 11944792 Review.
This paper describes services to help clients who are parents, which includes integration of adult's and children's services, long-term, home-based parent training, and linkage with community supports....
This paper describes services to help clients who are parents, which includes integration of adult's and children's services, long-term …