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Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT).
Paton NI, Stöhr W, Arenas-Pinto A, Clarke A, Williams I, Johnson M, Orkin C, Chen F, Lee V, Winston A, Gompels M, Fox J, Sanders K, Dunn DT; Protease Inhibitor monotherapy Versus Ongoing Triple therapy (PIVOT) Trial Team. Paton NI, et al. EClinicalMedicine. 2024 Feb 10;69:102457. doi: 10.1016/j.eclinm.2024.102457. eCollection 2024 Mar. EClinicalMedicine. 2024. PMID: 38361989 Free PMC article.
BACKGROUND: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy switch strategy. METHODS: Eligible participants attending 43 UK treatment centres had a viral load (VL) below 50 copies …
BACKGROUND: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes f …
Health-related quality of life in family caregivers of autistic adults.
Dückert S, Bart S, Gewohn P, König H, Schöttle D, Konnopka A, Rahlff P, Erik F, Vogeley K, Schulz H, David N, Peth J. Dückert S, et al. Among authors: david n. Front Psychiatry. 2023 Dec 18;14:1290407. doi: 10.3389/fpsyt.2023.1290407. eCollection 2023. Front Psychiatry. 2023. PMID: 38193135 Free PMC article.
DISCUSSION: Findings highlight the need to consider HRQoL (and caregiver burden) of family caregivers of autistic adults in several healthcare settings to monitor a potential comprised health status in early stages, with the long-term goal to improve family caregivers' HRQ …
DISCUSSION: Findings highlight the need to consider HRQoL (and caregiver burden) of family caregivers of autistic adults in several healthca …
Barriers and needs in mental healthcare of adults with autism spectrum disorder in Germany: a qualitative study in autistic adults, relatives, and healthcare providers.
Dückert S, Gewohn P, König H, Schöttle D, Konnopka A, Rahlff P, Erik F, Vogeley K, Schulz H, David N, Peth J. Dückert S, et al. Among authors: david n. BMC Psychiatry. 2023 Jul 21;23(1):528. doi: 10.1186/s12888-023-05026-x. BMC Psychiatry. 2023. PMID: 37479974 Free PMC article.
Even though symptoms persist from early childhood throughout the lifespan and often require long-term support, there is a lack of mental health services that sufficiently meet the needs of autistic adults. ...
Even though symptoms persist from early childhood throughout the lifespan and often require long-term support, there is a lack of men …
Design and Evaluation of Dissolvable Microneedles for Treating Atopic Dermatitis.
Ben David N, Richtman Y, Gross A, Ibrahim R, Nyska A, Ramot Y, Mizrahi B. Ben David N, et al. Pharmaceutics. 2023 Mar 31;15(4):1109. doi: 10.3390/pharmaceutics15041109. Pharmaceutics. 2023. PMID: 37111595 Free PMC article.
Treatment of moderate-to-severe symptomatic AD involves general skin care, restoration of the skin barrier function, and local anti-inflammatory drug combinations, and may also require systemic therapy, which is often associated with severe adverse effects and is occasionally uns …
Treatment of moderate-to-severe symptomatic AD involves general skin care, restoration of the skin barrier function, and local anti-inflamma …
Cell therapies for spinal cord injury: a review of the clinical trials and cell-type therapeutic potential.
Ribeiro BF, da Cruz BC, de Sousa BM, Correia PD, David N, Rocha C, Almeida RD, Ribeiro da Cunha M, Marques Baptista AA, Vieira SI. Ribeiro BF, et al. Among authors: david n. Brain. 2023 Jul 3;146(7):2672-2693. doi: 10.1093/brain/awad047. Brain. 2023. PMID: 36848323 Review.
Cell-based therapies hold neuroregenerative and neuroprotective potential, but, although being studied in SCI patients for more than two decades, long-term efficacy and safety remain unproven, and which cell types result in higher neurological and functional recovery remai …
Cell-based therapies hold neuroregenerative and neuroprotective potential, but, although being studied in SCI patients for more than two dec …
Outcomes following prenatal diagnosis of isolated persistent left superior vena cava.
Durand I, Hazelzet T, Gillibert A, Parrod C, David N, El Youssef F, Brehin AC, Barre E. Durand I, et al. Among authors: david n. Arch Cardiovasc Dis. 2022 Jun-Jul;115(6-7):335-347. doi: 10.1016/j.acvd.2022.03.005. Epub 2022 May 14. Arch Cardiovasc Dis. 2022. PMID: 35660361 Free article.
RESULTS: A total of 256 infants were included: 113 cases (44.1%) with isolated persistent left superior vena cava and 143 cases (55.9%) with associated malformations; respectively, 111 (98.2%) and 101 (70.6%) had a live birth. The median postnatal clinical follow-up was 3. …
RESULTS: A total of 256 infants were included: 113 cases (44.1%) with isolated persistent left superior vena cava and 143 cases (55.9%) with …
Long-Term Outcomes of the Excluded Rectum in Crohn's Disease: A Multicenter International Study.
Kassim G, Yzet C, Nair N, Debebe A, Rendon A, Colombel JF, Traboulsi C, Rubin DT, Maroli A, Coppola E, Carvello MM, Ben David N, De Lucia F, Sacchi M, Danese S, Spinelli A, Hirdes MMC, Ten Hove J, Oldenburg B, Cholapranee A, Riter M, Lukin D, Scherl E, Eren E, Sultan KS, Axelrad J, Sachar DB. Kassim G, et al. Among authors: ben david n. Inflamm Bowel Dis. 2023 Mar 1;29(3):417-422. doi: 10.1093/ibd/izac099. Inflamm Bowel Dis. 2023. PMID: 35522225 Free PMC article. Review.
BACKGROUND: Many patients with Crohn's disease (CD) require fecal diversion. To understand the long-term outcomes, we performed a multicenter review of the experience with retained excluded rectums. ...Only 14% remained symptom-free after reanastomosis, and only 6% if peri …
BACKGROUND: Many patients with Crohn's disease (CD) require fecal diversion. To understand the long-term outcomes, we performed a mul …
The Impact of the COVID-19 Pandemic on Independent Creative Activities in Two Large Cities in Romania.
Popa N, Pop AM, Marian-Potra AC, Cocean P, Hognogi GG, David NA. Popa N, et al. Among authors: david na. Int J Environ Res Public Health. 2021 Jul 19;18(14):7674. doi: 10.3390/ijerph18147674. Int J Environ Res Public Health. 2021. PMID: 34300125 Free PMC article.
The COVID-19 pandemic has had both financial and activity-related effects on a number of areas of activity, among which those involving the creative industries have proved to be weak in their capacity to survive the halting of all events held in physical spaces. The long-term
The COVID-19 pandemic has had both financial and activity-related effects on a number of areas of activity, among which those involving the …
Efficacy of Zoledronic Acid in Maintaining Areal and Volumetric Bone Density After Combined Denosumab and Teriparatide Administration: DATA-HD Study Extension.
Ramchand SK, David NL, Lee H, Eastell R, Tsai JN, Leder BZ. Ramchand SK, et al. Among authors: david nl. J Bone Miner Res. 2021 May;36(5):921-930. doi: 10.1002/jbmr.4259. Epub 2021 Feb 16. J Bone Miner Res. 2021. PMID: 33507574 Free article. Clinical Trial.
These data suggest that the DATA-HD Extension regimen may be an effective strategy in the long-term management of patients at high risk of fragility fracture. 2021 American Society for Bone and Mineral Research (ASBMR)....
These data suggest that the DATA-HD Extension regimen may be an effective strategy in the long-term management of patients at high ri …
Effects of Combination Denosumab and High-Dose Teriparatide Administration on Bone Microarchitecture and Estimated Strength: The DATA-HD HR-pQCT Study.
Ramchand SK, David NL, Lee H, Bruce M, Bouxsein ML, Leder BZ, Tsai JN. Ramchand SK, et al. Among authors: david nl. J Bone Miner Res. 2021 Jan;36(1):41-51. doi: 10.1002/jbmr.4161. Epub 2020 Sep 19. J Bone Miner Res. 2021. PMID: 32790196 Free article. Clinical Trial.
Improvements in trabecular microarchitecture at the distal tibia and estimated strength by micro-finite element analysis at both sites were numerically greater in the HD-group compared with SD-group but not significantly so. Together, these findings suggest that short-term
Improvements in trabecular microarchitecture at the distal tibia and estimated strength by micro-finite element analysis at both sites were …
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