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A Case of Community-Acquired Tuberculosis in an Infant Presenting with Pneumonia Refractory to Antibiotic Therapy.
Iness AN, Cruz AT, Dorfman SR, Sampayo EM. Iness AN, et al. Among authors: cruz at. J Educ Teach Emerg Med. 2023 Jan 31;8(1):V18-V22. doi: 10.21980/J8X07M. eCollection 2023 Jan. J Educ Teach Emerg Med. 2023. PMID: 37465039 Free PMC article.
Infant tuberculosis (TB) is a rare but potentially deadly infection and difficult to diagnose, especially in infants who may present with non-specific symptoms. Here, we report a case of an United States-born term infant with community-acquired miliary TB and no confirmed …
Infant tuberculosis (TB) is a rare but potentially deadly infection and difficult to diagnose, especially in infants who may present with no …
Defining pediatric community-acquired acute kidney injury: an observational study.
O'Neil ER, Devaraj S, Mayorquin L, Starke HE, Buffone GJ, Loftis LL, Arikan AA, Cruz AT. O'Neil ER, et al. Among authors: cruz at. Pediatr Res. 2020 Feb;87(3):564-568. doi: 10.1038/s41390-019-0577-3. Epub 2019 Sep 19. Pediatr Res. 2020. PMID: 31537011
BACKGROUND: Pediatric acute kidney injury (AKI) is associated with long-term morbidity and mortality; however, outcomes improve when AKI is detected earlier. ...
BACKGROUND: Pediatric acute kidney injury (AKI) is associated with long-term morbidity and mortality; however, outcomes improve when …
Monitoring Treatment of Childhood Tuberculosis and the Role of Therapeutic Drug Monitoring.
Cruz AT, Starke JR. Cruz AT, et al. Indian J Pediatr. 2019 Aug;86(8):732-739. doi: 10.1007/s12098-019-02882-y. Epub 2019 Feb 28. Indian J Pediatr. 2019. PMID: 30815840 Review.
Despite the infrequency of hepatotoxicity, the potential long-term impact of hepatic insufficiency dictates that all children receiving antimycobacterial therapy should be evaluated periodically by symptom screening and physical examination. ...
Despite the infrequency of hepatotoxicity, the potential long-term impact of hepatic insufficiency dictates that all children receivi …
Influenza A-Associated Epiglottitis and Compensatory Pursed Lip Breathing in an Infant.
OʼBryant SC, Lewis JD, Cruz AT, Mothner BA. OʼBryant SC, et al. Among authors: cruz at. Pediatr Emerg Care. 2019 Nov;35(11):e213-e216. doi: 10.1097/PEC.0000000000001589. Pediatr Emerg Care. 2019. PMID: 30247455
Here, we report the first case of epiglottitis secondary to influenza A in a former full-term, vaccinated infant who presented with cough, fever, stridor, pursed lip breathing, and progressive respiratory distress and eventual respiratory failure. ...
Here, we report the first case of epiglottitis secondary to influenza A in a former full-term, vaccinated infant who presented with c …
Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections.
Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, VanBuren JM, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network. Cruz AT, et al. JAMA Pediatr. 2017 Nov 6;171(11):e172927. doi: 10.1001/jamapediatrics.2017.2927. Epub 2017 Nov 6. JAMA Pediatr. 2017. PMID: 28892537 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: Planned secondary analysis of a prospective observational cohort study comprising 26 emergency departments in the Pediatric Emergency Care Applied Research Network from 2008 to 2013. We included febrile (38C), previously healthy, full-term …
DESIGN, SETTING, AND PARTICIPANTS: Planned secondary analysis of a prospective observational cohort study comprising 26 emergency department …
Evaluation and Management of Acute-Onset Hemiparesis in an Adolescent With Leukemia.
Subrahmanian KN, Shim YH, Shah MD, Tran BH, Stevens AM, Cruz AT. Subrahmanian KN, et al. Among authors: cruz at. Pediatr Emerg Care. 2018 Mar;34(3):e47-e50. doi: 10.1097/PEC.0000000000000837. Pediatr Emerg Care. 2018. PMID: 27668914
Emergency departments (EDs) are alert to the possibility of stroke and the need for early interventions to improve long-term clinical outcomes. However, new-onset hemiparesis in pediatric patients with leukemia may be due to a number of different etiologies, including most …
Emergency departments (EDs) are alert to the possibility of stroke and the need for early interventions to improve long-term clinical …
α- L-iduronidase gene-based therapy using the phiC31 system to treat mucopolysaccharidose type I mice.
Stilhano RS, Martin PK, de Melo SM, Samoto VY, Peres GB, da Silva Michelacci YM, da Silva FH, Pereira VG, D'Almeida V, da Cruz AT, Jasiulionis MG, Han SW. Stilhano RS, et al. Among authors: da cruz at. J Gene Med. 2015 Jan-Feb;17(1-2):1-13. doi: 10.1002/jgm.2818. J Gene Med. 2015. PMID: 25597593
CONCLUSIONS: phiC31-mediated gene therapy resulted in an important improvement in IDUA-/- mice, including locomotion, although the obstacles that need to be overcome to enable long-term gene therapy for MPSI are also noted....
CONCLUSIONS: phiC31-mediated gene therapy resulted in an important improvement in IDUA-/- mice, including locomotion, although the obstacles …