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Sex differences in thromboprophylaxis of the critically ill: a secondary analysis of a randomized trial.
Burns KEA, Heels-Ansdell D, Thabane L, Kahn SR, Lauzier F, Mehta S, Ostermann M, Bhuptani P, Crowther MA, Finfer S, Cook DJ; PROTECT Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Burns KEA, et al. Among authors: cook dj. Can J Anaesth. 2023 Jun;70(6):1008-1018. doi: 10.1007/s12630-023-02457-8. Epub 2023 Jun 13. Can J Anaesth. 2023. PMID: 37310606 Clinical Trial. English.
METHODS: We conducted unadjusted analyses using Cox proportional hazards analysis, stratified by centre and admission diagnostic category, including sex, treatment, and an interaction term. Additionally, we performed adjusted analyses and assessed the credibility of our fi …
METHODS: We conducted unadjusted analyses using Cox proportional hazards analysis, stratified by centre and admission diagnostic category, i …
Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis.
Fernando SM, Tran A, Sadeghirad B, Burns KEA, Fan E, Brodie D, Munshi L, Goligher EC, Cook DJ, Fowler RA, Herridge MS, Cardinal P, Jaber S, Møller MH, Thille AW, Ferguson ND, Slutsky AS, Brochard LJ, Seely AJE, Rochwerg B. Fernando SM, et al. Among authors: cook dj. Intensive Care Med. 2022 Feb;48(2):137-147. doi: 10.1007/s00134-021-06581-1. Epub 2021 Nov 25. Intensive Care Med. 2022. PMID: 34825256 Free article.
Compared to conventional oxygen therapy, neither NIPPV (OR 0.8 [95% CI 0.61-1.04], moderate certainty) or HFNC (OR 0.9 [95% CI 0.66-1.24], low certainty) reduced short-term mortality. Consistent findings were demonstrated across multiple subgroups, including high- and low- …
Compared to conventional oxygen therapy, neither NIPPV (OR 0.8 [95% CI 0.61-1.04], moderate certainty) or HFNC (OR 0.9 [95% CI 0.66-1.24], l …
Robotic Assessment of Upper Limb Function in a Nonhuman Primate Model of Chronic Stroke.
Chen Y, Poole MC, Olesovsky SV, Champagne AA, Harrison KA, Nashed JY, Coverdale NS, Scott SH, Cook DJ. Chen Y, et al. Among authors: cook dj. Transl Stroke Res. 2021 Aug;12(4):569-580. doi: 10.1007/s12975-020-00859-0. Epub 2021 Jan 3. Transl Stroke Res. 2021. PMID: 33393055
Stroke is a leading cause of death and disability worldwide and survivors are frequently left with long-term disabilities that diminish their autonomy and result in the need for chronic care. ...
Stroke is a leading cause of death and disability worldwide and survivors are frequently left with long-term disabilities that dimini …
Experiences of Bereaved Family Members Receiving Commemorative Paintings: A Qualitative Study.
Azad MA, Swinton M, Clarke FJ, Takaoka A, Vanstone M, Woods A, Boyle A, Hoad N, Toledo F, Piticaru J, Cook DJ. Azad MA, et al. Among authors: cook dj. JAMA Netw Open. 2020 Dec 1;3(12):e2027259. doi: 10.1001/jamanetworkopen.2020.27259. JAMA Netw Open. 2020. PMID: 33346843 Free PMC article.
IMPORTANCE: Although family members of patients who die in the intensive care unit commonly experience long-term psychological distress, end-of-life bereavement support programs for such relatives are uncommon. ...
IMPORTANCE: Although family members of patients who die in the intensive care unit commonly experience long-term psychological distre …
A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards.
Daneman N, Rishu AH, Pinto R, Arabi Y, Belley-Cote EP, Cirone R, Downing M, Cook DJ, Hall R, McGuinness S, McIntyre L, Muscedere J, Parke R, Reynolds S, Rogers BA, Shehabi Y, Shin P, Whitlock R, Fowler RA; Canadian Critical Care Trials Group. Daneman N, et al. Among authors: cook dj. Trials. 2020 Jan 15;21(1):92. doi: 10.1186/s13063-019-4033-9. Trials. 2020. PMID: 31941546 Free PMC article. Clinical Trial.
Frailty and associated outcomes and resource utilization following in-hospital cardiac arrest.
Fernando SM, McIsaac DI, Rochwerg B, Cook DJ, Bagshaw SM, Muscedere J, Munshi L, Nolan JP, Perry JJ, Downar J, Dave C, Reardon PM, Tanuseputro P, Kyeremanteng K. Fernando SM, et al. Among authors: cook dj. Resuscitation. 2020 Jan 1;146:138-144. doi: 10.1016/j.resuscitation.2019.11.011. Epub 2019 Nov 27. Resuscitation. 2020. PMID: 31785373
Secondary outcomes include return of spontaneous circulation (ROSC), discharge to long-term care, and hospital costs. We used multivariable logistic regression to adjust for known confounders. ...CONCLUSIONS: Frail individuals who experience an IHCA are more likely to die …
Secondary outcomes include return of spontaneous circulation (ROSC), discharge to long-term care, and hospital costs. We used multiva …
Frailty and invasive mechanical ventilation: association with outcomes, extubation failure, and tracheostomy.
Fernando SM, McIsaac DI, Rochwerg B, Bagshaw SM, Muscedere J, Munshi L, Ferguson ND, Seely AJE, Cook DJ, Dave C, Tanuseputro P, Kyeremanteng K. Fernando SM, et al. Among authors: cook dj. Intensive Care Med. 2019 Dec;45(12):1742-1752. doi: 10.1007/s00134-019-05795-8. Epub 2019 Oct 8. Intensive Care Med. 2019. PMID: 31595352
The primary outcome was hospital mortality. Secondary outcomes included discharge to long-term care, extubation failure at time of first liberation attempt, and tracheostomy. ...CONCLUSIONS: The presence of frailty among patients receiving mechanical ventilation is associa …
The primary outcome was hospital mortality. Secondary outcomes included discharge to long-term care, extubation failure at time of fi …
37 results