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Long-term outcomes after aortic root replacement for bicuspid aortic valve-associated aneurysm.
Rajesh K, Chung M, Levine D, Norton E, Patel P, Childress P, Zhao Y, Wang P, Leshnower B, Kurlansky P, Chen E, Takayama H. Rajesh K, et al. Among authors: chen e. J Thorac Cardiovasc Surg. 2024 Apr 5:S0022-5223(24)00204-6. doi: 10.1016/j.jtcvs.2024.03.003. Online ahead of print. J Thorac Cardiovasc Surg. 2024. PMID: 38691070
OBJECTIVE: Patients with congenital bicuspid aortic valve often require root replacement. This study aims to describe their long-term rates of mortality and reoperation. METHODS: This is a multicenter retrospective study of 747 patients with bicuspid aortic valve who under …
OBJECTIVE: Patients with congenital bicuspid aortic valve often require root replacement. This study aims to describe their long-term …
Quantitative Measurement of Serum HBcrAg Can Be Used to Assess the Feasibility of Safe Discontinuation of Antiviral Therapy for Chronic Hepatitis B.
Wang YH, Tang H, Chen EQ. Wang YH, et al. Among authors: chen eq. Viruses. 2024 Mar 29;16(4):529. doi: 10.3390/v16040529. Viruses. 2024. PMID: 38675872 Free PMC article. Review.
Current first-line therapeutics such as nucleos(t)ide analogues and interferons are unable to completely clear cccDNA, so the vast majority of patients need to take long-term or even lifelong medication. However, long-term virological and biochemical responses can b …
Current first-line therapeutics such as nucleos(t)ide analogues and interferons are unable to completely clear cccDNA, so the vast majority …
Short Report: CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation.
Wardell CM, Fung VCW, Chen E, Haque M, Gillies J, Spanier JA, Mojibian M, Fife BT, Levings MK. Wardell CM, et al. Among authors: chen e. bioRxiv [Preprint]. 2024 Apr 10:2024.04.06.588414. doi: 10.1101/2024.04.06.588414. bioRxiv. 2024. PMID: 38645184 Free PMC article. Preprint.
In tolerant mice, a significant proportion of BDC2.5 T cells gained FOXP3 expression suggesting that long-term tolerance is maintained by de novo Treg generation. Thus, A2-CAR Tregs mediate linked suppression and infectious tolerance and have potential therapeutic use to s …
In tolerant mice, a significant proportion of BDC2.5 T cells gained FOXP3 expression suggesting that long-term tolerance is maintaine …
Current clinical evidence is insufficient to support HMME-PDT as the first choice of treatment for young children with port wine birthmarks.
Gao C, Nguyen V, Hochman ML, Gao L, Chen EH, Friedman HI, Nelson JS, Tan W. Gao C, et al. Among authors: chen eh. Lasers Surg Med. 2024 Apr;56(4):321-333. doi: 10.1002/lsm.23779. Epub 2024 Mar 20. Lasers Surg Med. 2024. PMID: 38506454 Review.
The overall clearance rates for PDL were slightly, but not significantly, higher than those for HMME-PDT in cohorts with patients of all ages (C(0), 0.54 vs. 0.48, p = 0.733), subpopulations with only minors (C(0), 0.54 vs. 0.46, p = 0.714), and young children (C(0), 0.67 vs. 0.5 …
The overall clearance rates for PDL were slightly, but not significantly, higher than those for HMME-PDT in cohorts with patients of all age …
Acute type A aortic syndromes: outcomes are independent of aortic root/valve management.
Patel PM, Olakunle OE, Dong A, Chiou E, Wei J, Binongo J, Leshnower B, Chen EP. Patel PM, et al. Among authors: chen ep. Indian J Thorac Cardiovasc Surg. 2024 Mar;40(2):123-132. doi: 10.1007/s12055-023-01602-8. Epub 2023 Oct 19. Indian J Thorac Cardiovasc Surg. 2024. PMID: 38389780
For the total cohort, risk factors for late mortality included preoperative peripheral vascular disease (hazard ratio (HR) 2.3, 95% confidence interval (CI) 1.2-4.4, p = 0.009) and preoperative dialysis (HR 2.8, 95% CI 1.3-6.1, p = 0.01). CONCLUSION: Mid-term survival foll …
For the total cohort, risk factors for late mortality included preoperative peripheral vascular disease (hazard ratio (HR) 2.3, 95% confiden …
Effect of polymethyl methacrylate on in situ patterning of perovskite quantum dots by inkjet printing.
Zheng Y, Duan Y, Ye Y, Zheng X, Du A, Chen E, Xu S, Guo T. Zheng Y, et al. Among authors: chen e. Luminescence. 2024 Feb;39(2):e4691. doi: 10.1002/bio.4691. Luminescence. 2024. PMID: 38356146
The preparation of perovskite quantum dots (PQDs) using an in situ inkjet printing method is beneficial for improving the problems of aggregation and photoluminescence (PL) quenching during long-term storage. However, the stability of PQDs prepared using this method is sti …
The preparation of perovskite quantum dots (PQDs) using an in situ inkjet printing method is beneficial for improving the problems of aggreg …
Redo aortic surgery: Does one versus multiple affect outcomes?
Norton EL, Kalra K, Leshnower BG, Wei JW, Binongo JN, Chen EP. Norton EL, et al. Among authors: chen ep. JTCVS Open. 2023 Oct 4;16:158-166. doi: 10.1016/j.xjon.2023.09.035. eCollection 2023 Dec. JTCVS Open. 2023. PMID: 38204648 Free PMC article.
They were classified as aortic surgery after 1 previous surgery (first redo surgery, n = 360) and aortic surgery after 2 or more (multiple) previous surgeries (multiple redo surgery, n = 69). Postoperative outcomes and long-term survival were compared, and risk factors for …
They were classified as aortic surgery after 1 previous surgery (first redo surgery, n = 360) and aortic surgery after 2 or more (multiple) …
Lateral hypothalamic glutamatergic inputs to VTA glutamatergic neurons mediate prioritization of innate defensive behavior over feeding.
Barbano MF, Zhang S, Chen E, Espinoza O, Mohammad U, Alvarez-Bagnarol Y, Liu B, Hahn S, Morales M. Barbano MF, et al. Among authors: chen e. Nat Commun. 2024 Jan 9;15(1):403. doi: 10.1038/s41467-023-44633-w. Nat Commun. 2024. PMID: 38195566 Free PMC article.
Here, we demonstrated that LH-glutamatergic inputs to VTA promoted active avoidance, long-term aversion, and escape attempts. By testing feeding in the presence of a predator, we observed that ongoing feeding was decreased, and that this predator-induced decrease in feedin …
Here, we demonstrated that LH-glutamatergic inputs to VTA promoted active avoidance, long-term aversion, and escape attempts. By test …
Combinatorial Hypofractionated Radiotherapy and Pembrolizumab in Anaplastic Thyroid Cancer.
Tan JSH, Tay TKY, Ong EHW, Fehlings M, Tan DS, Sukma NB, Chen EX, Sng JH, Yip CSP, Lim KH, Lim DW, Iyer NG, Hwang JSG, Chua MLK, Ang MK. Tan JSH, et al. Among authors: chen ex. Eur Thyroid J. 2024 Jan 1;13(1):e230144. doi: 10.1530/ETJ-23-0144. Online ahead of print. Eur Thyroid J. 2024. PMID: 38181007 Free PMC article.
Conclusions Herein, we reported a case series of 5 patients with ATC, with 2 long-term survivors who were treated with surgical debulking followed by QUAD-shot RT and pembrolizumab, possibly due to synergy of local and systemic treatments in activating anti-tumour immunoge …
Conclusions Herein, we reported a case series of 5 patients with ATC, with 2 long-term survivors who were treated with surgical debul …
Antiviral Therapy Favors a Lower Risk of Liver Cirrhosis in HBeAg-negative Chronic Hepatitis B with Normal Alanine Transaminase and HBV DNA Positivity.
Zhou J, Wang FD, Li LQ, Li YJ, Wang SY, Chen EQ. Zhou J, et al. Among authors: chen eq. J Clin Transl Hepatol. 2023 Dec 28;11(7):1465-1475. doi: 10.14218/JCTH.2023.00272. Epub 2023 Aug 25. J Clin Transl Hepatol. 2023. PMID: 38161505 Free PMC article.
BACKGROUND AND AIMS: Direct evidence on the outcomes of hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients with normal alanine transaminase after long-term antiviral treatment is lacking. METHODS: HBeAg-negative patients with normal ALT and positive …
BACKGROUND AND AIMS: Direct evidence on the outcomes of hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients with norma …
367 results