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The Recruitment-Secretory Block ("R-SB") Phenomenon and Endoplasmic Reticulum Storage Diseases.
Callea F, Tomà P, Bellacchio E. Callea F, et al. Int J Mol Sci. 2021 Jun 24;22(13):6807. doi: 10.3390/ijms22136807. Int J Mol Sci. 2021. PMID: 34202771 Free PMC article. Review.
The Pi MZ phenotype of Alpha-1-antitrypsin deficiency (AATD) has turned out to be the key for in vivo studies of the reaction of the liver, as synthesis and block of secretion are concomitant. Indeed, the M fraction of AAT is stimulated for synthesis and regularly exported …
The Pi MZ phenotype of Alpha-1-antitrypsin deficiency (AATD) has turned out to be the key for in vivo studies of the reaction of the liver, …
The 2017 M Balasegaram Memorial Lecture: The Changing Landscape of Liver Diseases in Malaysia-60 Years On!
Goh KL. Goh KL. Malays J Med Sci. 2019 Mar;26(2):18-29. doi: 10.21315/mjms2019.26.2.3. Epub 2019 Apr 30. Malays J Med Sci. 2019. PMID: 31447605 Free PMC article. Review.
The most significant discoveries in hepatology have been that of hepatitis B virus in 1963 and hepatitis C virus in 1989, which have both been shown to be predominantly blood borne diseases. Hepatitis B and C infections result in long term carrier state and a high p …
The most significant discoveries in hepatology have been that of hepatitis B virus in 1963 and hepatitis C virus in 1989, which have both be …
A long-term carrier of cholera: cholera Dolores.
Azurin JC, Kobari K, Barua D, Alvero M, Gomez CZ, Dizon JJ, Nakano EI, Suplido R, Ledesma L. Azurin JC, et al. Bull World Health Organ. 1967;37(5):745-9. Bull World Health Organ. 1967. PMID: 5300877 Free PMC article.
The first known long-term carrier of cholera, found in the Philippines, is described. The carrier, Dolores M., who had suffered from El Tor cholera in August 1962, continued intermittently to excrete vibrios of the same characteristics as the original isolate …
The first known long-term carrier of cholera, found in the Philippines, is described. The carrier, Dolores M., who had …
Long term dynamics of a Streptococcus equi ssp equi outbreak, assessed by qPCR and culture and seM sequencing in silent carriers of strangles.
Riihimäki M, Aspán A, Ljung H, Pringle J. Riihimäki M, et al. Vet Microbiol. 2018 Sep;223:107-112. doi: 10.1016/j.vetmic.2018.07.016. Epub 2018 Jul 27. Vet Microbiol. 2018. PMID: 30173735
The aim of the study was to use culture, qPCR and seM sequencing to map Streptococcus equi subspec. equi (S.equi) isolates in long term carrier animals. A strangles outbreak affecting 41 Icelandic horses was followed to determine strangles free status using nasal an …
The aim of the study was to use culture, qPCR and seM sequencing to map Streptococcus equi subspec. equi (S.equi) isolates in long term …
Effect of dose on the immune response and persistence of Salmonella choleraesuis infection in swine.
Gray JT, Stabel TJ, Fedorka-Cray PJ. Gray JT, et al. Am J Vet Res. 1996 Mar;57(3):313-9. Am J Vet Res. 1996. PMID: 8669761
Short-term persistence can occur after a dose as low as 10(6) colony-forming units of S choleraesuis. Higher doses result in development of long-term carrier status, which may be related to the observed lymphocyte immunosuppression....
Short-term persistence can occur after a dose as low as 10(6) colony-forming units of S choleraesuis. Higher doses result in development of …
[Interrelation of virulent and avirulent (vaccinal) strains of Shigella flexneri 2A in long-term bacterial carriage in gnotobiotic rats].
Belaia IuA, Chakhava OV, Bystrova SM, Shustrova NM, Popova LIu. Belaia IuA, et al. Zh Mikrobiol Epidemiol Immunobiol. 1984 Mar;(3):82-9. Zh Mikrobiol Epidemiol Immunobiol. 1984. PMID: 6375221 Russian.
The ability of S. flexneri 2a virulent and avirulent (vaccine) strains No. 516 and No. 516 m to displace one another during long-term carrier state in germ-free rats has been studied. ...
The ability of S. flexneri 2a virulent and avirulent (vaccine) strains No. 516 and No. 516 m to displace one another during long-t …