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Should the enzyme name 'rhodesain' be discontinued?
Steverding D, Caffrey CR. Steverding D, et al. Among authors: caffrey cr. Mol Biochem Parasitol. 2021 Sep;245:111395. doi: 10.1016/j.molbiopara.2021.111395. Epub 2021 Jul 9. Mol Biochem Parasitol. 2021. PMID: 34246720
Accordingly, and based on a previously proposed terminology for kinetoplastid C1 peptidases (Caffrey and Steverding, 2009), we suggest the use of the formal term, TbrCATL, to denote the cathepsin L-like peptidases of the T. brucei subspecies. The earlier and informal te …
Accordingly, and based on a previously proposed terminology for kinetoplastid C1 peptidases (Caffrey and Steverding, 2009), we suggest the u …
Anthelmintic drug discovery: into the future.
Geary TG, Sakanari JA, Caffrey CR. Geary TG, et al. Among authors: caffrey cr. J Parasitol. 2015 Apr;101(2):125-33. doi: 10.1645/14-703.1. Epub 2015 Jan 13. J Parasitol. 2015. PMID: 25584662 Review.
The last half-century has provided all of the (few) drugs currently used to treat human helminthiases. Concern regarding the long-term utility of these drugs, given how readily resistance evolves in the veterinary-agricultural sector, spurs the discovery of new chemical en …
The last half-century has provided all of the (few) drugs currently used to treat human helminthiases. Concern regarding the long-term …
Recent initiatives and strategies to developing new drugs for tropical parasitic diseases.
Caffrey CR, Steverding D. Caffrey CR, et al. Expert Opin Drug Discov. 2008 Feb;3(2):173-86. doi: 10.1517/17460441.3.2.173. Expert Opin Drug Discov. 2008. PMID: 23480221
CONCLUSION: The tools, institutions and consortia are now in place and evolving to deliver new pharmaceuticals. Short-term results have already been realised in the clinic, mainly through the provision of new formulations of existing drugs. Long-term and consistent …
CONCLUSION: The tools, institutions and consortia are now in place and evolving to deliver new pharmaceuticals. Short-term results ha …