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Blocking cannabinoid activation of FAK and ERK1/2 compromises synaptic integrity in hippocampus.
Karanian DA, Brown QB, Makriyannis A, Bahr BA. Karanian DA, et al. Among authors: brown qb. Eur J Pharmacol. 2005 Jan 31;508(1-3):47-56. doi: 10.1016/j.ejphar.2004.12.009. Epub 2005 Jan 7. Eur J Pharmacol. 2005. PMID: 15680253
Here, cannabinergic activation of extracellular signal regulated-kinase (ERK) and focal adhesion kinase (FAK) occurred correspondingly in long-term hippocampal slice cultures. The stable endocannabinoid analogue R-methanandamide activated ERK1/ERK2 subtypes of mitogen-acti …
Here, cannabinergic activation of extracellular signal regulated-kinase (ERK) and focal adhesion kinase (FAK) occurred correspondingly in lo …