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Candida auris undergoes adhesin-dependent and -independent cellular aggregation.
Pelletier C, Shaw S, Alsayegh S, Brown AJP, Lorenz A. Pelletier C, et al. Among authors: brown ajp. PLoS Pathog. 2024 Mar 11;20(3):e1012076. doi: 10.1371/journal.ppat.1012076. eCollection 2024 Mar. PLoS Pathog. 2024. PMID: 38466738 Free PMC article.
Finally, we demonstrate that macrophages cannot clear aggregates, suggesting that aggregation might after all provide a benefit during systemic infection and could facilitate long-term persistence in the host....
Finally, we demonstrate that macrophages cannot clear aggregates, suggesting that aggregation might after all provide a benefit during syste …
Toward Digital Phenotypes of Early Childhood Mental Health via Unsupervised and Supervised Machine Learning.
Loftness BC, Rizzo DM, Halvorson-Phelan J, O'Leary A, Prytherch S, Bradshaw C, Brown AJ, Cheney N, McGinnis EW, McGinnis RS. Loftness BC, et al. Among authors: brown aj. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-4. doi: 10.1109/EMBC40787.2023.10340806. Annu Int Conf IEEE Eng Med Biol Soc. 2023. PMID: 38082795
Childhood mental health disorders such as anxiety, depression, and ADHD are commonly-occurring and often go undetected into adolescence or adulthood. This can lead to detrimental impacts on long-term wellbeing and quality of life. Current parent-report assessments for pre- …
Childhood mental health disorders such as anxiety, depression, and ADHD are commonly-occurring and often go undetected into adolescence or a …
Natural History and Clinical Outcomes After ST-Segment Elevation Myocardial Infarction Without Stent Insertion.
Nogic J, Cailes B, Yeoh J, Yudi M, Tong D, Farouque O, Brennan A, Dinh D, Brown AJ, Clark D. Nogic J, et al. Among authors: brown aj. Am J Cardiol. 2023 Dec 15;209:60-65. doi: 10.1016/j.amjcard.2023.09.096. Epub 2023 Oct 17. Am J Cardiol. 2023. PMID: 37863114
There remains ambiguity whether drug-eluting stent (DES) insertion or initial medical management is best practice. We sought to assess short-term clinical outcomes in patients presenting with STEMI without initial stent insertion. ...
There remains ambiguity whether drug-eluting stent (DES) insertion or initial medical management is best practice. We sought to assess short …
A novel role for PGE2-EP4 in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function.
Yarboro MT, Boatwright N, Sekulich DC, Hooper CW, Wong T, Poole SD, Berger CD, Brown AJ, Jetter CS, Sucre JMS, Shelton EL, Reese J. Yarboro MT, et al. Among authors: brown aj. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H687-H701. doi: 10.1152/ajpheart.00294.2023. Epub 2023 Aug 11. Am J Physiol Heart Circ Physiol. 2023. PMID: 37566109 Free PMC article.
However, in humans and mice, disrupted PGE(2)-EP(4) signaling in utero causes unexpected patency of the DA (PDA) after birth, suggesting another role for EP(4) during development. We used EP(4)-knockout (KO) mice and acute versus chronic pharmacological approaches to inves …
However, in humans and mice, disrupted PGE(2)-EP(4) signaling in utero causes unexpected patency of the DA (PDA) after birth, suggest …
Prognostic Value of Exercise Capacity in Kidney Transplant Candidates.
Tan S, Thang YW, Mulley WR, Polkinghorne KR, Ramkumar S, Cheng K, Chan J, Galligan J, Nolan M, Brown AJ, Moir S, Cameron JD, Nicholls SJ, Mottram PM, Nerlekar N. Tan S, et al. Among authors: brown aj. J Am Heart Assoc. 2022 Jun 21;11(12):e025862. doi: 10.1161/JAHA.121.025862. Epub 2022 Jun 14. J Am Heart Assoc. 2022. PMID: 35699178 Free PMC article.
Exercise stress testing allows the additional assessment of exercise capacity, which may have prognostic value for long-term cardiovascular outcomes in pre-transplant recipients. This study aimed to evaluate the prognostic value of exercise capacity on long-term car …
Exercise stress testing allows the additional assessment of exercise capacity, which may have prognostic value for long-term cardiova …
MAID ready for primetime?: A survey of SGO members regarding medical aid in dying (MAID).
Brown AJ, duPont N, Alvarez RD, Spillman MA, Landrum L, Lefkowits C. Brown AJ, et al. Gynecol Oncol Rep. 2021 Jul 5;37:100829. doi: 10.1016/j.gore.2021.100829. eCollection 2021 Aug. Gynecol Oncol Rep. 2021. PMID: 34277920 Free PMC article.
Most were female (58%), white (81%), and in academic practice (64%). Over 50% had heard the term MAID and have had a patient ask about it. Few (20%) reported living in a state where MAID is legal and 61% of these respondents provided MAID. ...
Most were female (58%), white (81%), and in academic practice (64%). Over 50% had heard the term MAID and have had a patient ask abou …
Acute Effects of Transcatheter Aortic Valve Replacement on Central Aortic Hemodynamics in Patients With Severe Aortic Stenosis.
Michail M, Hughes AD, Comella A, Cameron JN, Gooley RP, McCormick LM, Mathur A, Parker KH, Brown AJ, Cameron JD. Michail M, et al. Among authors: brown aj. Hypertension. 2020 Jun;75(6):1557-1564. doi: 10.1161/HYPERTENSIONAHA.119.14385. Epub 2020 Apr 20. Hypertension. 2020. PMID: 32306768 Free PMC article.
Relief of aortic stenosis by transcatheter aortic valve replacement (TAVR) is associated with both a short- and long-term hypertensive response. Counterintuitively, patients who are long-term normotensive post-TAVR have a worsened prognosis compared with patients wi …
Relief of aortic stenosis by transcatheter aortic valve replacement (TAVR) is associated with both a short- and long-term hypertensiv …
Off- vs. On-Pump Coronary Artery Bypass Grafting Long-Term Survival is Driven by Incompleteness of Revascularisation.
Thakur U, Nerlekar N, Muthalaly RG, Comella A, Wong NC, Cameron JD, Harper RW, Smith JA, Brown AJ. Thakur U, et al. Among authors: brown aj. Heart Lung Circ. 2020 Jan;29(1):149-155. doi: 10.1016/j.hlc.2018.11.019. Epub 2018 Dec 13. Heart Lung Circ. 2020. PMID: 30686645
We hypothesised that the inferior outcomes with off-pump CABG could be driven by the need for repeat revascularisation, with this benefit only becoming clear at long-term follow-up. We therefore evaluated short, medium and long-term outcomes of patients undergoing r …
We hypothesised that the inferior outcomes with off-pump CABG could be driven by the need for repeat revascularisation, with this benefit on …
Periprocedural Myocardial Injury Predicts Short- and Long-Term Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement.
Michail M, Cameron JN, Nerlekar N, Ihdayhid AR, McCormick LM, Gooley R, Niccoli G, Crea F, Montone RA, Brown AJ. Michail M, et al. Among authors: brown aj. Circ Cardiovasc Interv. 2018 Nov;11(11):e007106. doi: 10.1161/CIRCINTERVENTIONS.118.007106. Circ Cardiovasc Interv. 2018. PMID: 30571209
We performed a systematic review and meta-analysis to ascertain the association between PPMI and short- or long-term outcomes. METHODS AND RESULTS: Electronic searches identified studies reporting PPMI following TAVR. ...
We performed a systematic review and meta-analysis to ascertain the association between PPMI and short- or long-term outcomes. METHOD …
45 results