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Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry.
Aksu T, Tung R, De Potter T, Markman TM, Santangeli P, du Fay de Lavallaz J, Winterfield JR, Baykaner T, Alyesh D, Joza JE, Gopinathannair R, Badertscher P, Do DH, Hussein A, Osorio J, Dewland T, Perino A, Rodgers AJ, DeSimone C, Alfie A, Atwater BD, Singh D, Kumar K, Salcedo J, Bradfield JS, Upadhyay G, Sood N, Sharma PS, Gautam S, Kumar V, Forno ARJD, Woods CE, Rav-Acha M, Valeriano C, Kapur S, Enriquez A, Sundaram S, Glikson M, Gerstenfeld E, Piccini J, Tzou WS, Sauer W, d'Avila A, Shivkumar K, Huang HD. Aksu T, et al. Among authors: bradfield js. J Interv Card Electrophysiol. 2024 Mar 18. doi: 10.1007/s10840-024-01789-9. Online ahead of print. J Interv Card Electrophysiol. 2024. PMID: 38499825
METHODS: The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patient …
METHODS: The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) …
Ischemia-induced ventricular proarrhythmia and cardiovascular autonomic dysreflexia after cardioneuroablation.
Chung WH, Masuyama K, Challita R, Hayase J, Mori S, Cha S, Bradfield JS, Ardell JL, Shivkumar K, Ajijola OA. Chung WH, et al. Among authors: bradfield js. Heart Rhythm. 2023 Nov;20(11):1534-1545. doi: 10.1016/j.hrthm.2023.08.001. Epub 2023 Aug 9. Heart Rhythm. 2023. PMID: 37562487
BACKGROUND: Cardioneuroablation (CNA) is an attractive treatment of vasovagal syncope. Its long-term efficacy and safety remain unknown. OBJECTIVE: The purpose of this study was to develop a chronic porcine model of CNA to examine the susceptibility to ventricular tachyarr …
BACKGROUND: Cardioneuroablation (CNA) is an attractive treatment of vasovagal syncope. Its long-term efficacy and safety remain unkno …
Non-invasive Stereotactic Body Radiation Therapy for Refractory Ventricular Arrhythmias: Venturing into the Unknown.
Hayase J, Chin R, Cao M, Hu P, Shivkumar K, Bradfield JS. Hayase J, et al. Among authors: bradfield js. J Innov Card Rhythm Manag. 2022 Feb 15;13(2):4894-4899. doi: 10.19102/icrm.2022.130202. eCollection 2022 Feb. J Innov Card Rhythm Manag. 2022. PMID: 35251759 Free PMC article.
Numerous case reports and case series have provided encouraging short-term results suggesting good efficacy and safety, but randomized data and long-term outcomes are not yet available. ...
Numerous case reports and case series have provided encouraging short-term results suggesting good efficacy and safety, but randomize …
Recurrent ventricular tachycardia after cardiac sympathetic denervation: Prolonged cycle length with improved hemodynamic tolerance and ablation outcomes.
Hayase J, Dusi V, Do D, Ajijola OA, Vaseghi M, Lee JM, Yanagawa J, Hoftman N, Revels S, Buch EF, Khakpour H, Fujimura O, Krokhaleva Y, Macias C, Sorg J, Gima J, Pavez G, Boyle NG, Shivkumar K, Bradfield JS. Hayase J, et al. Among authors: bradfield js. J Cardiovasc Electrophysiol. 2020 Sep;31(9):2382-2392. doi: 10.1111/jce.14624. Epub 2020 Jun 30. J Cardiovasc Electrophysiol. 2020. PMID: 32558054 Free PMC article.
CONCLUSION: RFA for recurrent MMVT post-CSD is a reasonable treatment option with intermediate-term clinical success in 50% of patients. Clinical VT cycle length was significantly increased after CSD with associated improvement in mappable, hemodynamically tolerated VT dur …
CONCLUSION: RFA for recurrent MMVT post-CSD is a reasonable treatment option with intermediate-term clinical success in 50% of patien …
Hybrid surgical vs percutaneous access epicardial ventricular tachycardia ablation.
Li A, Hayase J, Do D, Buch E, Vaseghi M, Ajijola OA, Macias C, Krokhaleva Y, Khakpour H, Boyle NG, Benharash P, Biniwale R, Shivkumar K, Bradfield JS. Li A, et al. Among authors: bradfield js. Heart Rhythm. 2018 Apr;15(4):512-519. doi: 10.1016/j.hrthm.2017.11.009. Epub 2017 Nov 11. Heart Rhythm. 2018. PMID: 29132931
Surgical cases were propensity-matched to percutaneous epicardial ablation controls and short-term and long-term outcomes were compared. RESULTS: Between 2004 and 2016, 38 patients underwent 40 surgical epicardial access procedures (subxiphoid, n = 22; thoracotomy, …
Surgical cases were propensity-matched to percutaneous epicardial ablation controls and short-term and long-term outcomes were …
Incidence and significance of adhesions encountered during epicardial mapping and ablation of ventricular tachycardia in patients with no history of prior cardiac surgery or pericarditis.
Li A, Buch E, Boyle NG, Shivkumar K, Bradfield JS. Li A, et al. Among authors: bradfield js. Heart Rhythm. 2018 Jan;15(1):65-74. doi: 10.1016/j.hrthm.2017.09.007. Epub 2017 Sep 14. Heart Rhythm. 2018. PMID: 28917555
Adhesions were diagnosed with routine contrast pericardiography after pericardial entry. Demographics and long-term outcomes were compared between patients with and without adhesions. ...When present, they can limit mapping and may be associated with lower short-term …
Adhesions were diagnosed with routine contrast pericardiography after pericardial entry. Demographics and long-term outcomes were com …
Circadian variability patterns predict and guide premature ventricular contraction ablation procedural inducibility and outcomes.
Hamon D, Abehsira G, Gu K, Liu A, Blaye-Felice Sadron M, Billet S, Kambur T, Swid MA, Boyle NG, Dandamudi G, Maury P, Chen M, Miller JM, Lellouche N, Shivkumar K, Bradfield JS. Hamon D, et al. Among authors: bradfield js. Heart Rhythm. 2018 Jan;15(1):99-106. doi: 10.1016/j.hrthm.2017.07.034. Epub 2017 Jul 29. Heart Rhythm. 2018. PMID: 28765087
Isoproterenol washout or phenylephrine infusion was successful for the 3 S-HR-PVC patients, and no drug could increase PVC frequency in the 12 I-HR-PVC patients. Long-term RFA success rate in patients with frequent PVCs at baseline (82.9%) was similar to those with infrequ …
Isoproterenol washout or phenylephrine infusion was successful for the 3 S-HR-PVC patients, and no drug could increase PVC frequency in the …
Cardiac sympathetic denervation for intractable ventricular arrhythmias in Chagas disease.
Saenz LC, Corrales FM, Bautista W, Traina M, Meymandi S, Rodriguez DA, Tellez LJ, Vaseghi M, Garcia F, Shivkumar K, Bradfield JS. Saenz LC, et al. Among authors: bradfield js. Heart Rhythm. 2016 Jul;13(7):1388-94. doi: 10.1016/j.hrthm.2016.03.014. Epub 2016 Mar 9. Heart Rhythm. 2016. PMID: 26969783
Bilateral cardiac sympathetic denervation (BCSD) has shown promising results in the acute, intermediate, and long-term management of polymorphic and monomorphic ventricular tachycardia (VT) in patients with structural heart disease. ...
Bilateral cardiac sympathetic denervation (BCSD) has shown promising results in the acute, intermediate, and long-term management of …
A New Combined Parameter to Predict Premature Ventricular Complexes Induced Cardiomyopathy: Impact and Recognition of Epicardial Origin.
Hamon D, Blaye-Felice MS, Bradfield JS, Chaachoui N, Tung R, Elayi CS, Vaseghi M, Dhanjal TS, Boyle NG, Maury P, Shivkumar K, Lellouche N. Hamon D, et al. Among authors: bradfield js. J Cardiovasc Electrophysiol. 2016 Jun;27(6):709-17. doi: 10.1111/jce.12967. Epub 2016 Apr 7. J Cardiovasc Electrophysiol. 2016. PMID: 26924618
After a mean follow-up of 22.7 15.3 months, 72.9% achieved a long-term successful ablation and 54.2% had PVC-CMP. PVC-CMP prevalence was significantly higher in patients with an EPI compared to endocardial PVC focus (84.0% vs. 45.1%, respectively, P < 0.001). ...
After a mean follow-up of 22.7 15.3 months, 72.9% achieved a long-term successful ablation and 54.2% had PVC-CMP. PVC-CMP prevalence …
Renal Denervation: A Novel Therapy at the Crossroads of Imaging, Intervention, and Innovation.
Moriarty JM, Tung R, Bradfield JS, McWilliams J, Lee EW, Kuo MD. Moriarty JM, et al. Among authors: bradfield js. J Lab Autom. 2016 Apr;21(2):312-6. doi: 10.1177/2211068215605838. Epub 2015 Sep 17. J Lab Autom. 2016. PMID: 26384401
However, larger trials have shone an unfavorable light on the field, with concerns about the short- and long-term effectiveness, diverting attention back to operational and procedural details. ...
However, larger trials have shone an unfavorable light on the field, with concerns about the short- and long-term effectiveness, dive …