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Immunological Aspects of Kabuki Syndrome: A Retrospective Multicenter Study of the Italian Primary Immunodeficiency Network (IPINet).
Rossini L, Ricci S, Montin D, Azzari C, Gambineri E, Tellini M, Conti F, Pession A, Saettini F, Naviglio S, Valencic E, Magnolato A, Baselli L, Azzolini S, Consolini R, Leonardi L, D'Alba I, Carraro E, Romano R, Melis D, Stagi S, Cirillo E, Giardino G, Biffi A, Pignata C, Putti MC, Marzollo A. Rossini L, et al. Among authors: biffi a. J Clin Immunol. 2024 Apr 27;44(5):105. doi: 10.1007/s10875-024-01676-y. J Clin Immunol. 2024. PMID: 38676773
Individuals with cytopenia treated with mycophenolate as long-term immunomodulatory treatment (n = 4) showed complete response. ...
Individuals with cytopenia treated with mycophenolate as long-term immunomodulatory treatment (n = 4) showed complete response. ...
The sequential antifracturative treatment: a meta-analysis of randomized clinical trials.
Fassio A, Gatti D, Biffi A, Ronco R, Porcu G, Adami G, Alvaro R, Bogini R, Caputi AP, Cianferotti L, Frediani B, Gonnelli S, Iolascon G, Lenzi A, Leone S, Michieli R, Migliaccio S, Nicoletti T, Paoletta M, Pennini A, Piccirilli E, Rossini M, Brandi ML, Corrao G, Tarantino U. Fassio A, et al. Among authors: biffi a. Ther Adv Musculoskelet Dis. 2024 Apr 23;16:1759720X241234584. doi: 10.1177/1759720X241234584. eCollection 2024. Ther Adv Musculoskelet Dis. 2024. PMID: 38654732 Free PMC article.
BACKGROUND: Subjects with a fragility fracture have an increased risk of a new fracture and should receive effective strategies to prevent new events. The medium-term to long-term strategy should be scheduled by considering the mechanisms of action in therapy and th …
BACKGROUND: Subjects with a fragility fracture have an increased risk of a new fracture and should receive effective strategies to prevent n …
An empowered, clinically viable hematopoietic stem cell gene therapy for the treatment of multisystemic mucopolysaccharidosis type II.
Das S, Rruga F, Montepeloso A, Dimartino A, Spadini S, Corre G, Patel J, Cavalca E, Ferro F, Gatti A, Milazzo R, Galy A, Politi LS, Rizzardi GP, Vallanti G, Poletti V, Biffi A. Das S, et al. Among authors: biffi a. Mol Ther. 2024 Mar 6;32(3):619-636. doi: 10.1016/j.ymthe.2024.01.034. Epub 2024 Feb 3. Mol Ther. 2024. PMID: 38310355
Then the therapeutic LV was tested for its ability to efficiently and safely transduce bona fide human HSCs in clinically relevant conditions according to a standard vs. a novel protocol that demonstrated superior ability to transduce bona fide long-term repopulating HSCs. …
Then the therapeutic LV was tested for its ability to efficiently and safely transduce bona fide human HSCs in clinically relevant condition …
Prostaglandin E2 as transduction enhancer affects competitive engraftment of human hematopoietic stem and progenitor cells.
Poletti V, Montepeloso A, Pellin D, Biffi A. Poletti V, et al. Among authors: biffi a. Mol Ther Methods Clin Dev. 2023 Oct 11;31:101131. doi: 10.1016/j.omtm.2023.101131. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37920236 Free PMC article.
An ideal transduction protocol should determine high gene marking in long-term self-renewing hematopoietic stem cells (HSCs), preserving their repopulation potential during in vitro manipulation. ...
An ideal transduction protocol should determine high gene marking in long-term self-renewing hematopoietic stem cells (HSCs), preserv …
Severity of SARS-CoV-2 infection in a hospital population: a clinical comparison across age groups.
Rosazza C, Alagna L, Bandera A, Biffi A, Ciciriello F, Gramegna A, Lucidi V, Marchisio PG, Medino P, Muscatiello A, Uceda Renteria S, Colombo C. Rosazza C, et al. Among authors: biffi a. Ital J Pediatr. 2023 Oct 8;49(1):135. doi: 10.1186/s13052-023-01485-w. Ital J Pediatr. 2023. PMID: 37807040 Free PMC article.
In this study, we compared COVID-19-related outcomes and long-term complications between paediatric and adult patients infected by SARS-CoV-2. ...
In this study, we compared COVID-19-related outcomes and long-term complications between paediatric and adult patients infected by SA …
Disparities in brain health comorbidity management in intracerebral hemorrhage.
Mayerhofer E, Zaba NO, Parodi L, Ganbold AS, Biffi A, Rosand J, Yechoor N, Anderson CD. Mayerhofer E, et al. Among authors: biffi a. Front Neurol. 2023 Jun 8;14:1194810. doi: 10.3389/fneur.2023.1194810. eCollection 2023. Front Neurol. 2023. PMID: 37360335 Free PMC article.
Future trials should evaluate whether using the ICH hospitalization to systematically address co-morbidities can improve long-term outcomes....
Future trials should evaluate whether using the ICH hospitalization to systematically address co-morbidities can improve long-term ou …
Relationship between hemoglobin, hemolysis, and transcranial Doppler velocities in children with sickle cell disease: Results from a long-term natural history study in Italy in the era of multimodal therapy.
Reggiani G, Coppadoro B, Munaretto V, Pieroni A, Viaro F, Manara R, Beaubrun A, Biffi A, Baracchini C, Sainati L, Colombatti R. Reggiani G, et al. Among authors: biffi a. Eur J Haematol. 2023 Sep;111(3):414-422. doi: 10.1111/ejh.14022. Epub 2023 Jun 6. Eur J Haematol. 2023. PMID: 37282348
Elucidating the relationship between cerebral hemodynamics and hemolytic anemia can help identify novel therapeutic approaches to reduce stroke risk and transfusion dependence. METHODS: This long-term, real-world study was designed to evaluate the prevalence of TCD imaging …
Elucidating the relationship between cerebral hemodynamics and hemolytic anemia can help identify novel therapeutic approaches to reduce str …
Hypogammaglobulinemia in Children After Hematopoietic Stem Cell Transplantation and Rituximab Treatment: Relevance of B Cell Subsets.
Marzollo A, Serena T, Mainardi C, Calore E, Pillon M, Carraro E, Tosato F, Biffi A, Tumino M. Marzollo A, et al. Among authors: biffi a. J Pediatr Hematol Oncol. 2023 Jan 1;45(1):e145-e149. doi: 10.1097/MPH.0000000000002582. Epub 2022 Nov 17. J Pediatr Hematol Oncol. 2023. PMID: 36598967
We analyzed 5 patients (cases group) requiring immunoglobulin substitution due to low level of IgG (IgG <5 g/L) detected after RTX treatment and 5 patients (controls group) not requiring long-term immunoglobulin (Ig) substitution. We investigated the B cell reconstituti …
We analyzed 5 patients (cases group) requiring immunoglobulin substitution due to low level of IgG (IgG <5 g/L) detected after RTX treatm …
Association of Depression Onset and Treatment With Blood Pressure Control After Intracerebral Hemorrhage.
Keins S, Abramson JR, Mallick A, Castello JP, Rodriguez-Torres A, Popescu D, Hoffman D, Kourkoulis C, Gurol ME, Greenberg SM, Anderson CD, Viswanathan A, Rosand J, Biffi A. Keins S, et al. Among authors: biffi a. Stroke. 2023 Jan;54(1):105-112. doi: 10.1161/STROKEAHA.122.040331. Epub 2022 Nov 29. Stroke. 2023. PMID: 36444719
BACKGROUND: Blood pressure (BP) control represents a crucial intervention to improve long-term outcomes following spontaneous intracerebral hemorrhage (ICH). ...Primary outcomes included systolic and diastolic BP measurements during long-term follow-up after ICH. RE …
BACKGROUND: Blood pressure (BP) control represents a crucial intervention to improve long-term outcomes following spontaneous intrace …
51 results