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Hemoadsorption: Consensus report of the 30th Acute Disease Quality Initiative workgroup.
Ankawi G, Bagshaw SM, Bellomo R, Baldwin I, Basu R, Bottari G, Cantaluppi V, Clark W, De Rosa S, Forni LG, Fuhrman D, Goldstein S, Gomez H, Husain-Syed F, Joannidis M, Kashani K, Lorenzin A, Mehta R, Murray PT, Murugan R, Ostermann M, Pannu N, Premuzic V, Prowle J, Reis T, Rimmelé T, Ronco C, Rosner M, Schneider A, See E, Soranno D, Villa G, Whaley-Connell A, Zarbock A. Ankawi G, et al. Among authors: bellomo r. Nephrol Dial Transplant. 2024 Apr 15:gfae089. doi: 10.1093/ndt/gfae089. Online ahead of print. Nephrol Dial Transplant. 2024. PMID: 38621759
The data show that hemoadsorption has clinically acceptable short-term biocompatibility and safety, technical feasibility, and experimental demonstration of specified target molecule removal. ...
The data show that hemoadsorption has clinically acceptable short-term biocompatibility and safety, technical feasibility, and experi …
Association of perioperative transfusion of fresh frozen plasma and outcomes after cardiac surgery.
Hinton JV, Xing Z, Fletcher C, Perry LA, Karamesinis A, Shi J, Penny-Dimri JC, Ramson D, Coulson TG, Segal R, Smith JA, Williams-Spence J, Weinberg L, Bellomo R. Hinton JV, et al. Among authors: bellomo r. Acta Anaesthesiol Scand. 2024 Mar 11. doi: 10.1111/aas.14406. Online ahead of print. Acta Anaesthesiol Scand. 2024. PMID: 38467589
FFP transfusion was associated with 30-day mortality (odds ratio (OR), 1.41; 99% CI, 1.17-1.71; p < .0001), but not with long-term mortality (hazard ratio (HR), 0.92; 99% CI, 0.85-1.00; p = .007, Holm-Bonferroni alpha = 0.0004). ...

FFP transfusion was associated with 30-day mortality (odds ratio (OR), 1.41; 99% CI, 1.17-1.71; p < .0001), but not with long-term

Expedited organ donation in Victoria, Australia: donor characteristics and donation outcomes.
D'Costa RL, Radford S, Opdam HI, McDonald M, McEvoy L, Bellomo R. D'Costa RL, et al. Among authors: bellomo r. Crit Care Resusc. 2023 Oct 18;22(4):303-311. doi: 10.51893/2020.4.OA2. eCollection 2020 Dec. Crit Care Resusc. 2023. PMID: 38046868 Free PMC article.

For the kidney recipients, early graft dysfunction requiring dialysis was more common than with organs from the standard pathway (71% v 38%; P < 0.0001); however, short and medium term graft and patient survival were similar. Three recipients from the expedited pool exp

For the kidney recipients, early graft dysfunction requiring dialysis was more common than with organs from the standard pathway (71% v 38%; …
The role of renin-angiotensin system in sepsis-associated acute kidney injury: mechanisms and therapeutic implications.
Garcia B, Zarbock A, Bellomo R, Legrand M. Garcia B, et al. Among authors: bellomo r. Curr Opin Crit Care. 2023 Dec 1;29(6):607-613. doi: 10.1097/MCC.0000000000001092. Epub 2023 Sep 21. Curr Opin Crit Care. 2023. PMID: 37861190 Review.
PURPOSE OF REVIEW: This review aims to explore the relationship between the renin angiotensin system (RAS) and sepsis-associated acute kidney injury (SA-AKI), a common complication in critically ill patients associated with mortality, morbidity, and long-term cardiovascula …
PURPOSE OF REVIEW: This review aims to explore the relationship between the renin angiotensin system (RAS) and sepsis-associated acute kidne …
The effect of recombinant erythropoietin on long-term outcome after moderate-to-severe traumatic brain injury.
Skrifvars MB, Luethi N, Bailey M, French C, Nichol A, Trapani T, McArthur C, Arabi YM, Bendel S, Cooper DJ, Bellomo R; EPO-TBI Investigators, the ANZICS Clinical Trials Group. Skrifvars MB, et al. Among authors: bellomo r. Intensive Care Med. 2023 Jul;49(7):831-839. doi: 10.1007/s00134-023-07141-5. Epub 2023 Jul 5. Intensive Care Med. 2023. PMID: 37405413 Free PMC article.
PURPOSE: Recombinant erythropoietin (EPO) administered for traumatic brain injury (TBI) may increase short-term survival, but the long-term effect is unknown. METHODS: We conducted a pre-planned long-term follow-up of patients in the multicentre erythropoieti …
PURPOSE: Recombinant erythropoietin (EPO) administered for traumatic brain injury (TBI) may increase short-term survival, but the lon …
Sepsis-associated acute kidney injury-treatment standard.
Zarbock A, Koyner JL, Gomez H, Pickkers P, Forni L; Acute Disease Quality Initiative group. Zarbock A, et al. Nephrol Dial Transplant. 2023 Dec 20;39(1):26-35. doi: 10.1093/ndt/gfad142. Nephrol Dial Transplant. 2023. PMID: 37401137 Review.
Despite these advancements, SA-AKI remains a critical clinical condition and a major health burden, and further studies are needed to diminish the short and long-term consequences of SA-AKI. We review the current treatment standards and discuss novel developments in the pa …
Despite these advancements, SA-AKI remains a critical clinical condition and a major health burden, and further studies are needed to dimini …
Sodium glucose co-transporter-2 inhibitors in intensive care unit patients with type 2 diabetes: a pilot case control study.
Mårtensson J, Cutuli SL, Osawa EA, Yanase F, Toh L, Cioccari L, Luethi N, Maeda A, Bellomo R. Mårtensson J, et al. Among authors: bellomo r. Crit Care. 2023 May 16;27(1):189. doi: 10.1186/s13054-023-04481-y. Crit Care. 2023. PMID: 37194077 Free PMC article.
BACKGROUND: Sodium glucose co-transporter-2 (SGLT2) inhibitors improve long-term cardiovascular and renal outcomes in individuals with type 2 diabetes. ...
BACKGROUND: Sodium glucose co-transporter-2 (SGLT2) inhibitors improve long-term cardiovascular and renal outcomes in individuals wit …
Association of Perioperative Cryoprecipitate Transfusion and Mortality After Cardiac Surgery.
Hinton JV, Xing Z, Fletcher CM, Perry LA, Karamesinis A, Shi J, Ramson DM, Penny-Dimri JC, Liu Z, Williams-Spence J, Coulson TG, Smith JA, Segal R, Bellomo R. Hinton JV, et al. Among authors: bellomo r. Ann Thorac Surg. 2023 Aug;116(2):401-411. doi: 10.1016/j.athoracsur.2023.02.054. Epub 2023 Mar 12. Ann Thorac Surg. 2023. PMID: 36914040
Postoperative cryoprecipitate transfusion was associated with reduced operative mortality (odds ratio [OR], 0.82; 99% CI, 0.69-0.97; P = .002) and long-term mortality (hazard ratio, 0.92; 99% CI, 0.87-0.97; P = .0042). ...CONCLUSIONS: In a large, multicenter cohort study a …
Postoperative cryoprecipitate transfusion was associated with reduced operative mortality (odds ratio [OR], 0.82; 99% CI, 0.69-0.97; P = .00 …
The Prognostic Significance of Red Cell Distribution Width in Cardiac Surgery: A Systematic Review and Meta-Analysis.
Frentiu AA, Mao K, Caruana CB, Raveendran D, Perry LA, Penny-Dimri JC, Ramson DM, Segal R, Bellomo R, Smith JA, Liu Z. Frentiu AA, et al. Among authors: bellomo r. J Cardiothorac Vasc Anesth. 2023 Mar;37(3):471-479. doi: 10.1053/j.jvca.2022.11.015. Epub 2022 Nov 20. J Cardiothorac Vasc Anesth. 2023. PMID: 36635145 Review.
The authors included 26 studies involving 48,092 patients who had undergone cardiac surgery. Elevated preoperative RDW was associated with long-term mortality (pooled HR 1.63, 95% CI 1.05-2.52), short-term mortality (pooled OR 2.16, 95% CI 1.21-3.87), acute kidney i …
The authors included 26 studies involving 48,092 patients who had undergone cardiac surgery. Elevated preoperative RDW was associated with l …
Comparing the Clinical Frailty Scale and an International Classification of Diseases-10 Modified Frailty Index in Predicting Long-Term Survival in Critically Ill Patients.
Subramaniam A, Ueno R, Tiruvoipati R, Darvall J, Srikanth V, Bailey M, Pilcher D, Bellomo R. Subramaniam A, et al. Among authors: bellomo r. Crit Care Explor. 2022 Oct 13;4(10):e0777. doi: 10.1097/CCE.0000000000000777. eCollection 2022 Oct. Crit Care Explor. 2022. PMID: 36259062 Free PMC article.
OBJECTIVE: To compare the performance of CFS and a recently developed International Classification of Diseases-10 (ICD-10) mFI (ICD-10mFI) as frailty-based predictors of long-term survival for up to 1 year. DESIGN: A retrospective multicentric observational study. ...The m …
OBJECTIVE: To compare the performance of CFS and a recently developed International Classification of Diseases-10 (ICD-10) mFI (ICD-10mFI) a …
121 results