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Closed-loop ventilation.
Arnal JM, Katayama S, Howard C. Arnal JM, et al. Curr Opin Crit Care. 2023 Feb 1;29(1):19-25. doi: 10.1097/MCC.0000000000001012. Epub 2022 Dec 9. Curr Opin Crit Care. 2023. PMID: 36484170 Review.
Large, multicenter randomized controlled trials are needed to assess their impact on important short- and long-term clinical outcomes, the organization of the ICU, and cost-effectiveness....
Large, multicenter randomized controlled trials are needed to assess their impact on important short- and long-term clinical outcomes …
Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis.
Bendiab E, Garnier F, Soler M, Fosset M, Jaber S, Molinari N, Jung B; BICAR-ICU Investigators. Bendiab E, et al. Crit Care Med. 2023 Jan 1;51(1):e1-e12. doi: 10.1097/CCM.0000000000005706. Epub 2022 Nov 8. Crit Care Med. 2023. PMID: 36351174 Clinical Trial.
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high short-term mortality. Since the long-term prognosis of these patients is unknown, we aimed to determine the long-term hea …
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high sh …
In COPD, Nocturnal Noninvasive Ventilation Reduces the FIO2 Delivered Compared With Long-Term Oxygen Therapy at the Same Flow.
Cardinale M, Cungi PJ, Esnault P, Castagna O, Nguyen C, Daranda E, Bordes J, Arnal JM, Meaudre E, Goutorbe P. Cardinale M, et al. Among authors: arnal jm. Respir Care. 2020 Dec;65(12):1897-1903. doi: 10.4187/respcare.07570. Epub 2020 Jul 21. Respir Care. 2020. PMID: 32694183 Free article.
BACKGROUND: Nocturnal noninvasive ventilation is recommended for patients with hypercapnic COPD. Long-term oxygen therapy improves survival in patients with hypoxemic disease. ...It might explain the poor results in all but 2 randomized controlled trials on long-term …
BACKGROUND: Nocturnal noninvasive ventilation is recommended for patients with hypercapnic COPD. Long-term oxygen therapy improves su …
Noninvasive ventilation: education and training. A narrative analysis and an international consensus document.
Karim HMR, Burns KEA, Ciobanu LD, El-Khatib M, Nicolini A, Vargas N, Hernández-Gilsoul T, Skoczyński S, Falcone VA, Arnal JM, Bach J, De Santo LS, Lucchini A, Steier J, Purro A, Petroianni A, Sassoon CS, Bambi S, Aguiar M, Soubani AO, Taniguchi C, Mollica C, Berlin DA, Piervincenzi E, Rao F, Luigi FS, Ferrari R, Garuti G, Laier-Groeneveld G, Fiorentino G, Ho KM, Alqahtani JS, Luján M, Moerer O, Resta O, Pierucci P, Papadakos P, Steiner S, Stieglitz S, Dikmen Y, Duan J, Bhakta P, Iglesias AU, Corcione N, Caldeira V, Karakurt Z, Valli G, Kondili E, Ruggieri MP, Raposo MS, Bottino F, Soler-González R, Gurjar M, Sandoval-Gutierrez JL, Jafari B, Arroyo-Cozar M, Noval AR, Corcione N, Barjaktarevic I, Sarc I, Mina B, Szkulmowski Z, Taniguchi C, Esquinas AM. Karim HMR, et al. Among authors: arnal jm. Adv Respir Med. 2019;87(1):36-45. doi: 10.5603/ARM.a2019.0006. Epub 2019 Mar 4. Adv Respir Med. 2019. PMID: 30830962 Free article.
The use of NIV is expanding over the time and if properly applied, it can save patients' lives and improve long-term prognosis. However, both knowledge and skills of its proper use as life support are paramount. ...
The use of NIV is expanding over the time and if properly applied, it can save patients' lives and improve long-term prognosis. Howev …
Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry.
Chelly J, Plantefève G, Kamel T, Bruel C, Nseir S, Lai C, Cirillo G, Skripkina E, Ehrminger S, Berdaguer-Ferrari FD, Le Marec J, Paul M, Autret A, Deye N; ACICOVID-19 study group. Chelly J, et al. Ann Intensive Care. 2021 Nov 13;11(1):155. doi: 10.1186/s13613-021-00945-y. Ann Intensive Care. 2021. PMID: 34773516 Free PMC article.
TRIAL REGISTRATION: This study was retrospectively registered in ClinicalTrials.gov (NTC04373759) in April 2020 ( https://www.clinicaltrials.gov/ct2/show/NCT04373759?term=acicovid&draw=2&rank=1 )....
TRIAL REGISTRATION: This study was retrospectively registered in ClinicalTrials.gov (NTC04373759) in April 2020 ( https://www.clinicaltrials …
Effect of neuromuscular blocking agents on gas exchange in patients presenting with acute respiratory distress syndrome.
Gainnier M, Roch A, Forel JM, Thirion X, Arnal JM, Donati S, Papazian L. Gainnier M, et al. Among authors: arnal jm. Crit Care Med. 2004 Jan;32(1):113-9. doi: 10.1097/01.CCM.0000104114.72614.BC. Crit Care Med. 2004. PMID: 14707568 Clinical Trial.
Two-way repeated-measures analysis of variance exhibited a decrease in positive end-expiratory pressure over time (p =.036). Concerning short-term effects, there was no modification of PaO2/FiO2 ratio 1 hr after randomization in either group. ...
Two-way repeated-measures analysis of variance exhibited a decrease in positive end-expiratory pressure over time (p =.036). Concerning shor …
Respiratory support in COPD patients after acute exacerbation with monitoring the quality of support (Rescue2-monitor): an open-label, prospective randomized, controlled, superiority clinical trial comparing hospital- versus home-based acute non-invasive ventilation for patients with hypercapnic chronic obstructive pulmonary disease.
Rescue2-monitor group. Rescue2-monitor group. Trials. 2020 Oct 22;21(1):877. doi: 10.1186/s13063-020-04672-w. Trials. 2020. PMID: 33092618 Free PMC article. Clinical Trial.
These pathophysiological factors might influence the success of home NIV in stable COPD, thus long-term NIV specifically adapted to a patient's "phenotype" is likely to improve prognosis, reduce readmission to hospital, and prevent death. ...
These pathophysiological factors might influence the success of home NIV in stable COPD, thus long-term NIV specifically adapted to a …
Airway and transpulmonary driving pressures and mechanical powers selected by INTELLiVENT-ASV in passive, mechanically ventilated ICU patients.
Arnal JM, Saoli M, Garnero A. Arnal JM, et al. Heart Lung. 2020 Jul-Aug;49(4):427-434. doi: 10.1016/j.hrtlng.2019.11.001. Epub 2019 Nov 14. Heart Lung. 2020. PMID: 31733881
For the 19 patients managed with transpulmonary pressure deltaP(L) was 6 (4 - 7) cmH2O and MP(L) was 3.6 (3.1 - 4.4) J/min. CONCLUSIONS: In this short term observation study, INTELLiVENT-ASV selected deltaP and MP considered in safe ranges for lung protection. ...
For the 19 patients managed with transpulmonary pressure deltaP(L) was 6 (4 - 7) cmH2O and MP(L) was 3.6 (3.1 - 4.4) J/min. CONCLUSIONS: In …