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[Adults with cystic fibrosis. It's not just about longevity].
von der Hardt H, Schwarz C, Ullrich G. von der Hardt H, et al. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Apr;55(4):558-67. doi: 10.1007/s00103-012-1460-0. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012. PMID: 22441526 German.
Since 2009, for the first time CF adults have made up the majority of patients in the German CF registry. The drawbacks of improved longevity are long-term complications (e.g., CFRD, osteoporosis) that were rarely seen before. ...
Since 2009, for the first time CF adults have made up the majority of patients in the German CF registry. The drawbacks of improved longevit …
Long term azithromycin therapy in cystic fibrosis patients: a study on drug levels and sputum properties.
Baumann U, King M, App EM, Tai S, König A, Fischer JJ, Zimmermann T, Sextro W, von der Hardt H. Baumann U, et al. Among authors: von der hardt h. Can Respir J. 2004 Mar;11(2):151-5. doi: 10.1155/2004/747841. Can Respir J. 2004. PMID: 15045047 Free article. Clinical Trial.
BACKGROUND: Following reports on the treatment of diffuse panbronchiolitis (DPB), recent studies demonstrate that long term therapy with azithromycin (AZM) is effective in cystic fibrosis (CF) patients. ...
BACKGROUND: Following reports on the treatment of diffuse panbronchiolitis (DPB), recent studies demonstrate that long term therapy w …
Phosphatidylcholine molecular species in lung surfactant: composition in relation to respiratory rate and lung development.
Bernhard W, Hoffmann S, Dombrowsky H, Rau GA, Kamlage A, Kappler M, Haitsma JJ, Freihorst J, von der Hardt H, Poets CF. Bernhard W, et al. Among authors: von der hardt h. Am J Respir Cell Mol Biol. 2001 Dec;25(6):725-31. doi: 10.1165/ajrcmb.25.6.4616. Am J Respir Cell Mol Biol. 2001. PMID: 11726398
Labeling experiments with [methyl-(3)H]choline in mice and perfused rat lungs demonstrated identical alveolar proportions of total and newly synthesized PC16:0/14:0, PC16:0/16:1, and PC16:0/16:0, which were much higher than those of other phosphatidylcholine species. In surfactan …
Labeling experiments with [methyl-(3)H]choline in mice and perfused rat lungs demonstrated identical alveolar proportions of total and newly …
Buccal adherence of Pseudomonas aeruginosa in patients with cystic fibrosis under long-term therapy with azithromycin.
Baumann U, Fischer JJ, Gudowius P, Lingner M, Herrmann S, Tümmler B, von der Hardt H. Baumann U, et al. Among authors: von der hardt h. Infection. 2001 Jan-Feb;29(1):7-11. doi: 10.1007/s15010-001-0031-3. Infection. 2001. PMID: 11261763
Following therapy with AZM adherence decreased in all patients by 70% or 5.6 to 2.4 (1.1) bacteria/cell (p = 0.007), representing close to normal LeveLs (1.2 +/- 0.6). CONCLUSION: Long-term low-dose AZM therapy may improve the compromised oropharyngeaL barrier function in …
Following therapy with AZM adherence decreased in all patients by 70% or 5.6 to 2.4 (1.1) bacteria/cell (p = 0.007), representing close to n …
[Surgery of acquired laryngotracheal stenoses in childhood. Experiences and results from 1988 to 1998. I: Laryngotracheal reconstruction].
Vollrath M, Freihorst J, von der Hardt H. Vollrath M, et al. Among authors: von der hardt h. HNO. 1999 May;47(5):457-65. doi: 10.1007/s001060050405. HNO. 1999. PMID: 10412654 German.
Subglottic laryngotracheal stenosis represents the most severe intubation injury and is increasingly encountered in children due to long-term ventilation during intensive care treatment. Since more than 90% of these children have tracheostomies their physical, psychosocial …
Subglottic laryngotracheal stenosis represents the most severe intubation injury and is increasingly encountered in children due to long- …
Active surfactant in pharyngeal aspirates of term neonates: lipid biochemistry and surface tension function.
Poets CF, Arning A, Bernhard W, Acevedo C, von der Hardt H. Poets CF, et al. Among authors: von der hardt h. Eur J Clin Invest. 1997 Apr;27(4):293-8. doi: 10.1046/j.1365-2362.1997.1050655.x. Eur J Clin Invest. 1997. PMID: 9134377
The methods used in this study allowed for complete PL and surface tension analyses of surfactant obtained during routine pharyngeal suctioning after delivery at term. Whether they are also applicable to preterm neonates with respiratory distress remains to be determined.. …
The methods used in this study allowed for complete PL and surface tension analyses of surfactant obtained during routine pharyngeal suction …
Comparative hygienic surveillance of contamination with pseudomonads in a cystic fibrosis ward over a 4-year period.
Bosshammer J, Fiedler B, Gudowius P, von der Hardt H, Römling U, Tümmler B. Bosshammer J, et al. Among authors: von der hardt h. J Hosp Infect. 1995 Dec;31(4):261-74. doi: 10.1016/0195-6701(95)90205-8. J Hosp Infect. 1995. PMID: 8926376
In order to study the long-term distribution and population dynamics of Pseudomonas aeruginosa strains in a highly contaminated hospital environment, two 4-week epidemiological studies, with an interval of 4 years, were carried out in the cystic fibrosis (CF) ward of the P …
In order to study the long-term distribution and population dynamics of Pseudomonas aeruginosa strains in a highly contaminated hospi …
Improvement of nutritional status and lung function after long-term nocturnal gastrostomy feedings in cystic fibrosis.
Steinkamp G, von der Hardt H. Steinkamp G, et al. Among authors: von der hardt h. J Pediatr. 1994 Feb;124(2):244-9. doi: 10.1016/s0022-3476(94)70312-4. J Pediatr. 1994. PMID: 8301431
We investigated weight gain and clinical course of 14 patients with cystic fibrosis (CF), aged 7 to 23 years, who received long-term nocturnal supplemental feedings by means of percutaneous endoscopic gastrostomies (PEGs). ...
We investigated weight gain and clinical course of 14 patients with cystic fibrosis (CF), aged 7 to 23 years, who received long-term …
[Juvenile laryngeal papillomatosis--a case report].
Gappa M, Freihorst J, Seidenberg J, Vollrath M, von der Hardt H. Gappa M, et al. Among authors: von der hardt h. Pneumologie. 1991 Nov;45(11):936-8. Pneumologie. 1991. PMID: 1763007 German.
According to the present state of knowledge, a combination of laser coagulation and alpha-interferon therapy is the treatment of choice. It can be applied on a long-term basis effectively and with few side effects due to individualised dosage determination. We report on a …
According to the present state of knowledge, a combination of laser coagulation and alpha-interferon therapy is the treatment of choice. It …
21 results