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1984 1
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1999 1
2001 1
2006 1
2007 2
2008 1
2009 1
2010 1
2013 2
2014 1
2016 1
2017 3
2018 1
2024 0

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16 results

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Page 1
Thrombolysis in acute ischemic stroke: controlled trials and clinical experience.
Hacke W, Brott T, Caplan L, Meier D, Fieschi C, von Kummer R, Donnan G, Heiss WD, Wahlgren NG, Spranger M, Boysen G, Marler JR. Hacke W, et al. Among authors: von kummer r. Neurology. 1999;53(7 Suppl 4):S3-14. Neurology. 1999. PMID: 10532643 Review.
The most substantial treatment barrier is the narrow time window, which may be expanded if long-term experience shows that this is possible. Most stroke patients arrive at the hospital too late to be eligible for screening and treatment. ...
The most substantial treatment barrier is the narrow time window, which may be expanded if long-term experience shows that this is po …
Impact of Thrombus Length on Outcomes After Intra-Arterial Aspiration Thrombectomy in the THERAPY Trial.
Yoo AJ, Khatri P, Mocco J, Zaidat OO, Gupta R, Frei D, Lopes D, Shownkeen H, Berkhemer OA, Meyer D, Hak SS, Kuo SS, Buell H, Bose A, Sit SP, von Kummer R; THERAPY Trial Investigators. Yoo AJ, et al. Among authors: von kummer r. Stroke. 2017 Jul;48(7):1895-1900. doi: 10.1161/STROKEAHA.116.016253. Epub 2017 Jun 8. Stroke. 2017. PMID: 28596447 Clinical Trial.
Increasing TL was associated with greater aspiration thrombectomy treatment effect (interaction term P=0.03). This might be related to a potentially stronger adverse effect of increasing TL on 90-day modified Rankin Scale for patients treated with IV r-tPA (rho=0.39; P=0.0 …
Increasing TL was associated with greater aspiration thrombectomy treatment effect (interaction term P=0.03). This might be related t …
Effect of IV alteplase on the ischemic brain lesion at 24-48 hours after ischemic stroke.
Mair G, von Kummer R, Morris Z, von Heijne A, Bradey N, Cala L, Peeters A, Farrall AJ, Adami A, Potter G, Sandercock PAG, Lindley RI, Wardlaw JM; IST-3 Collaborative Group. Mair G, et al. Among authors: von kummer r. Neurology. 2018 Nov 27;91(22):e2067-e2077. doi: 10.1212/WNL.0000000000006575. Epub 2018 Oct 26. Neurology. 2018. PMID: 30366975 Free PMC article. Clinical Trial.
In meta-analysis of 6 trials including IST-3 (n = 4,757), allocation to alteplase was associated with a reduction in ischemic lesion extent on follow-up imaging (OR = 0.85, 95% CI 0.76-0.95, p = 0.004). CONCLUSION: Alteplase was associated with reduced short-term progressi …
In meta-analysis of 6 trials including IST-3 (n = 4,757), allocation to alteplase was associated with a reduction in ischemic lesion extent …
Neuroborreliosis-associated cerebral vasculitis: long-term outcome and health-related quality of life.
Back T, Grünig S, Winter Y, Bodechtel U, Guthke K, Khati D, von Kummer R. Back T, et al. Among authors: von kummer r. J Neurol. 2013 Jun;260(6):1569-75. doi: 10.1007/s00415-013-6831-4. Epub 2013 Jan 18. J Neurol. 2013. PMID: 23329377
Previously, cerebral vasculitis has been regarded as an extremely rare complication of neuroborreliosis. The data on the long-term outcome in patients with cerebral vasculitis due to neuroborreliosis are limited. ...
Previously, cerebral vasculitis has been regarded as an extremely rare complication of neuroborreliosis. The data on the long-term ou …
Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?
Berger C, Fiorelli M, Steiner T, Schäbitz WR, Bozzao L, Bluhmki E, Hacke W, von Kummer R. Berger C, et al. Among authors: von kummer r. Stroke. 2001 Jun;32(6):1330-5. doi: 10.1161/01.str.32.6.1330. Stroke. 2001. PMID: 11387495
BACKGROUND AND PURPOSE: The term symptomatic hemorrhage secondary to ischemic stroke implies a clear causal relationship between clinical deterioration and hemorrhagic transformation (HT) regardless of the type of HT. ...
BACKGROUND AND PURPOSE: The term symptomatic hemorrhage secondary to ischemic stroke implies a clear causal relationship between clin …
Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials.
Lees KR, Emberson J, Blackwell L, Bluhmki E, Davis SM, Donnan GA, Grotta JC, Kaste M, von Kummer R, Lansberg MG, Lindley RI, Lyden P, Murray GD, Sandercock PA, Toni D, Toyoda K, Wardlaw JM, Whiteley WN, Baigent C, Hacke W, Howard G; Stroke Thrombolysis Trialists’ Collaborators Group. Lees KR, et al. Among authors: von kummer r. Stroke. 2016 Sep;47(9):2373-9. doi: 10.1161/STROKEAHA.116.013644. Epub 2016 Aug 9. Stroke. 2016. PMID: 27507856 Free PMC article. Clinical Trial.
Ordinal logistic regression models assessed treatment differences after adjustment for treatment delay, age, stroke severity, and relevant interaction term(s). RESULTS: Treatment with alteplase was beneficial for a delay in treatment extending to 4.5 hours after stroke ons …
Ordinal logistic regression models assessed treatment differences after adjustment for treatment delay, age, stroke severity, and relevant i …
Altered neural network supporting declarative long-term memory in mild cognitive impairment.
Poettrich K, Weiss PH, Werner A, Lux S, Donix M, Gerber J, von Kummer R, Fink GR, Holthoff VA. Poettrich K, et al. Among authors: von kummer r. Neurobiol Aging. 2009 Feb;30(2):284-98. doi: 10.1016/j.neurobiolaging.2007.05.027. Epub 2007 Jul 17. Neurobiol Aging. 2009. PMID: 17644222
Autobiographical episodic memory represents a subsystem of declarative long-term memory and largely depends on combining information from multiple sources. ...Our data suggest that MCI leads to a loss of specificity in the neural network supporting declarative long-term …
Autobiographical episodic memory represents a subsystem of declarative long-term memory and largely depends on combining information …
Safety and efficacy of thrombectomy in acute ischaemic stroke (REVASCAT): 1-year follow-up of a randomised open-label trial.
Dávalos A, Cobo E, Molina CA, Chamorro A, de Miquel MA, Román LS, Serena J, López-Cancio E, Ribó M, Millán M, Urra X, Cardona P, Tomasello A, Castaño C, Blasco J, Aja L, Rubiera M, Gomis M, Renú A, Lara B, Martí-Fàbregas J, Jankowitz B, Cerdà N, Jovin TG; REVASCAT Trial Investigators. Dávalos A, et al. Lancet Neurol. 2017 May;16(5):369-376. doi: 10.1016/S1474-4422(17)30047-9. Epub 2017 Mar 16. Lancet Neurol. 2017. PMID: 28318984 Clinical Trial.
However, whether the observed benefit is sustained in the long term remains unknown. We report the results of the prespecified 12-month analysis of the REVASCAT trial. ...These findings have important clinical and public health implications for evaluating the cost-effectiv …
However, whether the observed benefit is sustained in the long term remains unknown. We report the results of the prespecified 12-mon …
Observed Cost and Variations in Short Term Cost-Effectiveness of Therapy for Ischemic Stroke in Interventional Management of Stroke (IMS) III.
Simpson KN, Simpson AN, Mauldin PD, Palesch YY, Yeatts SD, Kleindorfer D, Tomsick TA, Foster LD, Demchuk AM, Khatri P, Hill MD, Jauch EC, Jovin TG, Yan B, von Kummer R, Molina CA, Goyal M, Schonewille WJ, Mazighi M, Engelter ST, Anderson C, Spilker J, Carrozzella J, Ryckborst KJ, Janis LS, Broderick JP; Interventional Management of Stroke (IMS) III Investigators. Simpson KN, et al. Among authors: von kummer r. J Am Heart Assoc. 2017 May 8;6(5):e004513. doi: 10.1161/JAHA.116.004513. J Am Heart Assoc. 2017. PMID: 28483774 Free PMC article. Clinical Trial.
The kind of resources used postdischarge also varied between treatment groups. Incremental short-term cost-effectiveness ratios varied greatly when treatments were compared for patient subgroups. ...
The kind of resources used postdischarge also varied between treatment groups. Incremental short-term cost-effectiveness ratios varie …
Association of sleep apnea with clinically silent microvascular brain tissue changes in acute cerebral ischemia.
Kepplinger J, Barlinn K, Boehme AK, Gerber J, Puetz V, Pallesen LP, Schrempf W, Dzialowski I, Albright KC, Alexandrov AV, Reichmann H, von Kummer R, Bodechtel U. Kepplinger J, et al. Among authors: von kummer r. J Neurol. 2014 Feb;261(2):343-9. doi: 10.1007/s00415-013-7200-z. Epub 2013 Nov 30. J Neurol. 2014. PMID: 24292644 Free PMC article.
Routine sleep apnea screening and further investigation of possible long-term effects of non-invasive ventilatory treatment of sleep apnea appear warranted in this at-risk population....
Routine sleep apnea screening and further investigation of possible long-term effects of non-invasive ventilatory treatment of sleep …
16 results