Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

72 results

Filters applied: . Clear all
Page 1
No additional risk of congenital anomalies after first-trimester dydrogesterone use: a systematic review and meta-analysis.
Katalinic A, Noftz MR, Garcia-Velasco JA, Shulman LP, van den Anker JN, Strauss Iii JF. Katalinic A, et al. Among authors: van den anker jn. Hum Reprod Open. 2024 Jan 23;2024(1):hoae004. doi: 10.1093/hropen/hoae004. eCollection 2024. Hum Reprod Open. 2024. PMID: 38344249 Free PMC article. Review.
As congenital anomalies are mostly reported as secondary outcomes, the search term 'safety' was added. PARTICIPANTS/MATERIALS SETTING METHODS: Interventional study and observational study (OS) designs were eligible for inclusion. ...J.F.S. has patents related to diagnosis …
As congenital anomalies are mostly reported as secondary outcomes, the search term 'safety' was added. PARTICIPANTS/MATERIALS SETTING …
A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia.
Krzyzanski W, Wintermark P, Annaert P, Groenendaal F, Şahin S, Öncel MY, Armangil D, Koc E, Battin MR, Gunn AJ, Frymoyer A, Chock VY, Keles E, Mekahli D, van den Anker J, Smits A, Allegaert K. Krzyzanski W, et al. Among authors: van den anker j. AAPS J. 2023 Dec 5;26(1):4. doi: 10.1208/s12248-023-00851-0. AAPS J. 2023. PMID: 38051395
The data consisted of sCr observations up to 10 days of postnatal age in neonates who underwent TH during the first 3 days after birth. Available covariates were birth weight (BWT), gestational age (GA), survival, and acute kidney injury (AKI). ...This model predict …
The data consisted of sCr observations up to 10 days of postnatal age in neonates who underwent TH during the first 3 days after birth …
Melatonin as a Therapy for Preterm Brain Injury: What Is the Evidence?
Häusler S, Robertson NJ, Golhen K, van den Anker J, Tucker K, Felder TK. Häusler S, et al. Among authors: van den anker j. Antioxidants (Basel). 2023 Aug 17;12(8):1630. doi: 10.3390/antiox12081630. Antioxidants (Basel). 2023. PMID: 37627625 Free PMC article. Review.
Despite significant improvements in survival following preterm birth in recent years, the neurodevelopmental burden of prematurity, with its long-term cognitive and behavioral consequences, remains a significant challenge in neonatology. ...
Despite significant improvements in survival following preterm birth in recent years, the neurodevelopmental burden of prematurity, w …
Efficacy and Safety of Vamorolone vs Placebo and Prednisone Among Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial.
Guglieri M, Clemens PR, Perlman SJ, Smith EC, Horrocks I, Finkel RS, Mah JK, Deconinck N, Goemans N, Haberlova J, Straub V, Mengle-Gaw LJ, Schwartz BD, Harper AD, Shieh PB, De Waele L, Castro D, Yang ML, Ryan MM, McDonald CM, Tulinius M, Webster R, McMillan HJ, Kuntz NL, Rao VK, Baranello G, Spinty S, Childs AM, Sbrocchi AM, Selby KA, Monduy M, Nevo Y, Vilchez-Padilla JJ, Nascimento-Osorio A, Niks EH, de Groot IJM, Katsalouli M, James MK, van den Anker J, Damsker JM, Ahmet A, Ward LM, Jaros M, Shale P, Dang UJ, Hoffman EP. Guglieri M, et al. Among authors: van den anker j. JAMA Neurol. 2022 Oct 1;79(10):1005-1014. doi: 10.1001/jamaneurol.2022.2480. JAMA Neurol. 2022. PMID: 36036925 Free PMC article. Clinical Trial.
IMPORTANCE: Corticosteroidal anti-inflammatory drugs are widely prescribed but long-term use shows adverse effects that detract from patient quality of life. ...Vamorolone may be a safer alternative than prednisone in this disease, in which long-term corticosteroid …
IMPORTANCE: Corticosteroidal anti-inflammatory drugs are widely prescribed but long-term use shows adverse effects that detract from …
What babies need: accelerating access to current and novel antiretroviral drugs in neonates through pharmacokinetic studies.
Jacobs TG, Schouwenburg S, Penazzato M, Archary M, Ruel TD, van den Anker J, Burger DM, Cressey TR, Abrams EJ, Lyall H, Bekker A, Colbers A; Penta Clinical Pharmacology Working Group; PADO-HIV 5 participants. Jacobs TG, et al. Among authors: van den anker j. Lancet HIV. 2022 Sep;9(9):e649-e657. doi: 10.1016/S2352-3018(22)00121-7. Epub 2022 Jul 18. Lancet HIV. 2022. PMID: 35863363 Review.
Although 23 antiretroviral drugs are approved for use in adults, only six are approved by regulatory authorities for use in term neonates born to women with HIV, with even fewer options for preterm neonates. ...
Although 23 antiretroviral drugs are approved for use in adults, only six are approved by regulatory authorities for use in term neon …
Population pharmacokinetics and dosing optimization of mezlocillin in neonates and young infants.
Zhou J, Jiang L, Zhang ZL, Wang ZR, Zhang YX, Lin X, Tang BH, Yao BF, Guo ZX, Yang JJ, Van Den Anker J, Wu YE, Zhao W. Zhou J, et al. Among authors: van den anker j. J Antimicrob Chemother. 2022 Jul 28;77(8):2238-2244. doi: 10.1093/jac/dkac176. J Antimicrob Chemother. 2022. PMID: 35662337
RESULTS: Ninety-five blood samples from 48 neonates and young infants were included. The ranges of postmenstrual age and birth weight were 29-40 weeks and 1200-4000 g, respectively, including term and preterm infants. ...
RESULTS: Ninety-five blood samples from 48 neonates and young infants were included. The ranges of postmenstrual age and birth weight …
Efficacy and safety of low-dose versus high-dose hydrocortisone to treat hypotension in neonates: a protocol for a systematic review and meta-analysis.
Sushko K, Al-Rawahi N, Watterberg K, Van Den Anker J, Litalien C, Lacroix J, Razak A, Samiee-Zafarghandy S. Sushko K, et al. Among authors: van den anker j. BMJ Paediatr Open. 2021 Dec;5(1):e001200. doi: 10.1136/bmjpo-2021-001200. BMJ Paediatr Open. 2021. PMID: 35404836 Free PMC article.
BACKGROUND: Impaired adrenal function is a well-described entity in critically ill term and preterm neonates with systemic hypotension. The standard treatment for neonatal hypotension includes volume expanders and vasopressors. ...METHODS: We will conduct a systematic revi …
BACKGROUND: Impaired adrenal function is a well-described entity in critically ill term and preterm neonates with systemic hypotensio …
Long-Term Safety of Prenatal and Neonatal Exposure to Paracetamol: A Systematic Review.
Patel R, Sushko K, van den Anker J, Samiee-Zafarghandy S. Patel R, et al. Among authors: van den anker j. Int J Environ Res Public Health. 2022 Feb 14;19(4):2128. doi: 10.3390/ijerph19042128. Int J Environ Res Public Health. 2022. PMID: 35206317 Free PMC article. Review.
Despite the frequent use of paracetamol, concerns have been raised regarding the high variability in neonatal dosing regimens and the long-term safety of early life exposure. OBJECTIVE: To investigate the available evidence on the long-term safety of prenatal and ne …
Despite the frequent use of paracetamol, concerns have been raised regarding the high variability in neonatal dosing regimens and the long- …
Simultaneous pharmacokinetic/pharmacodynamic (PKPD) assessment of ampicillin and gentamicin in the treatment of neonatal sepsis.
Gastine S, Obiero C, Kane Z, Williams P, Readman J, Murunga S, Thitiri J, Ellis S, Correia E, Nyaoke B, Kipper K, van den Anker J, Sharland M, Berkley JA, Standing JF. Gastine S, et al. Among authors: van den anker j. J Antimicrob Chemother. 2022 Feb 2;77(2):448-456. doi: 10.1093/jac/dkab413. J Antimicrob Chemother. 2022. PMID: 35107141 Free PMC article. Clinical Trial.
A common clearance for both drugs was used (6.89 L/h/70 kg) relating to glomerular filtration (CLGFR), with an additional clearance term added for ampicillin (5.3 L/h/70 kg). Covariate modelling included a priori allometric weight and post-menstrual age scaling of clearanc …
A common clearance for both drugs was used (6.89 L/h/70 kg) relating to glomerular filtration (CLGFR), with an additional clearance term …
Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants.
Ganguly S, Edginton AN, Gerhart JG, Cohen-Wolkowiez M, Greenberg RG, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Ganguly S, et al. Clin Pharmacokinet. 2021 Dec;60(12):1591-1604. doi: 10.1007/s40262-021-01046-6. Epub 2021 Jun 22. Clin Pharmacokinet. 2021. PMID: 34155614 Free PMC article.
We applied physiologically based pharmacokinetic (PBPK) modeling to characterize the disposition of meropenem in preterm and term infants. METHODS: An adult meropenem PBPK model was developed in PK-Sim() (Version 8) and scaled to infants accounting for renal transporter on …
We applied physiologically based pharmacokinetic (PBPK) modeling to characterize the disposition of meropenem in preterm and term inf …
72 results