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Randomized Placebo-Controlled Trial to Evaluate Effects of Eplerenone on Myocardial Perfusion and Function Among Persons With Human Immunodeficiency Virus (HIV)-Results From the MIRACLE HIV Study.
Srinivasa S, Walpert AR, Thomas TS, Huck DM, Jerosch-Herold M, Islam S, Lu MT, Burdo TH, deFilippi CR, Dunderdale CN, Feldpausch M, Iyengar S, Shen G, Baak S, Torriani M, Robbins GK, Lee H, Kwong R, DiCarli M, Adler GK, Grinspoon SK. Srinivasa S, et al. Among authors: defilippi cr. Clin Infect Dis. 2023 Oct 13;77(8):1166-1175. doi: 10.1093/cid/ciad310. Clin Infect Dis. 2023. PMID: 37243345 Clinical Trial.
CLINICAL TRIALS REGISTRATION: NCT02740179 (https://clinicaltrials.gov/ct2/show/NCT02740179?term=NCT02740179&draw=2&rank=1)....
CLINICAL TRIALS REGISTRATION: NCT02740179 (https://clinicaltrials.gov/ct2/show/NCT02740179?term=NCT02740179&draw=2&rank=1)... …
A Standardized and Regionalized Network of Care for Cardiogenic Shock.
Tehrani BN, Sherwood MW, Rosner C, Truesdell AG, Ben Lee S, Damluji AA, Desai M, Desai S, Epps KC, Flanagan MC, Howard E, Ibrahim N, Kennedy J, Moukhachen H, Psotka M, Raja A, Saeed I, Shah P, Singh R, Sinha SS, Tang D, Welch T, Young K, deFilippi CR, Speir A, O'Connor CM, Batchelor WB. Tehrani BN, et al. Among authors: defilippi cr. JACC Heart Fail. 2022 Oct;10(10):768-781. doi: 10.1016/j.jchf.2022.04.004. Epub 2022 Jun 8. JACC Heart Fail. 2022. PMID: 36175063 Free PMC article.
CONCLUSIONS: Spoke and hub patients experienced similar short-term outcomes within a regionalized CS network. The optimal strategy to promote standardized care and improved outcomes across regional CS networks merits further investigation....
CONCLUSIONS: Spoke and hub patients experienced similar short-term outcomes within a regionalized CS network. The optimal strategy to …
Cardiogenic Shock From Heart Failure Versus Acute Myocardial Infarction: Clinical Characteristics, Hospital Course, and 1-Year Outcomes.
Sinha SS, Rosner CM, Tehrani BN, Maini A, Truesdell AG, Lee SB, Bagchi P, Cameron J, Damluji AA, Desai M, Desai SS, Epps KC, deFilippi C, Flanagan MC, Genovese L, Moukhachen H, Park JJ, Psotka MA, Raja A, Shah P, Sherwood MW, Singh R, Tang D, Young KD, Welch T, O'Connor CM, Batchelor WB. Sinha SS, et al. Among authors: defilippi c. Circ Heart Fail. 2022 Jun;15(6):e009279. doi: 10.1161/CIRCHEARTFAILURE.121.009279. Epub 2022 May 5. Circ Heart Fail. 2022. PMID: 35510546 Free PMC article.
Although patients with HF-CS had lower in-hospital and 1-year mortality, both cohorts experienced similarly high rates of postdischarge major adverse cardiovascular and cerebrovascular events and 30-day readmission, highlighting that both cohorts warrant careful long-term …
Although patients with HF-CS had lower in-hospital and 1-year mortality, both cohorts experienced similarly high rates of postdischarge majo …
Adverse cardiac mechanics and incident coronary heart disease in the Cardiovascular Health Study.
Massera D, Hu M, Delaney JA, Bartz TM, Bach ME, Dvorak SJ, DeFilippi CR, Psaty BM, Gottdiener JS, Kizer JR, Shah SJ. Massera D, et al. Among authors: defilippi cr. Heart. 2022 Apr;108(7):529-535. doi: 10.1136/heartjnl-2021-319296. Epub 2021 Jul 13. Heart. 2022. PMID: 34257074 Free PMC article.
We investigated the relationship of LV longitudinal strain, LV early diastolic strain rate (SR) and left atrial (LA) reservoir strain with long-term CHD incidence in community-dwelling older adults. METHODS: The association of all three strain measures with incidence of no …
We investigated the relationship of LV longitudinal strain, LV early diastolic strain rate (SR) and left atrial (LA) reservoir strain with l …
Predicting Long-Term Absence of Coronary Artery Calcium in Metabolic Syndrome and Diabetes: The MESA Study.
Razavi AC, Wong N, Budoff M, Bazzano LA, Kelly TN, He J, Fernandez C, Lima J, Polak JF, Mongraw-Chaffin M, deFilippi C, Szklo M, Bertoni AG, Blumenthal RS, Blaha MJ, Whelton SP. Razavi AC, et al. Among authors: defilippi c. JACC Cardiovasc Imaging. 2021 Jan;14(1):219-229. doi: 10.1016/j.jcmg.2020.06.047. Epub 2020 Oct 28. JACC Cardiovasc Imaging. 2021. PMID: 33129732 Free PMC article.
RESULTS: The mean age of participants was 58.9 years, 67% were women, 422 participants had MetS, and 152 had T2D. The proportion with long-term CAC=0 was similar for MetS (42%) and T2D (44%). A younger age was the only individual low/normal traditional risk factor associat …
RESULTS: The mean age of participants was 58.9 years, 67% were women, 422 participants had MetS, and 152 had T2D. The proportion with long- …
Combining Biomarkers and Imaging for Short-Term Assessment of Cardiovascular Disease Risk in Apparently Healthy Adults.
Gore MO, Ayers CR, Khera A, deFilippi CR, Wang TJ, Seliger SL, Nambi V, Selvin E, Berry JD, Hundley WG, Budoff M, Greenland P, Drazner MH, Ballantyne CM, Levine BD, de Lemos JA. Gore MO, et al. Among authors: defilippi cr. J Am Heart Assoc. 2020 Aug 4;9(15):e015410. doi: 10.1161/JAHA.119.015410. Epub 2020 Jul 23. J Am Heart Assoc. 2020. PMID: 32698652 Free PMC article.
Background Current strategies for cardiovascular disease (CVD) risk assessment focus on 10-year or longer timeframes. Shorter-term CVD risk is also clinically relevant, particularly for high-risk occupations, but is under-investigated. ...
Background Current strategies for cardiovascular disease (CVD) risk assessment focus on 10-year or longer timeframes. Shorter-term CV …
HfN Nanoparticles: An Unexplored Catalyst for the Electrocatalytic Oxygen Evolution Reaction.
Defilippi C, Shinde DV, Dang Z, Manna L, Hardacre C, Greer AJ, D'Agostino C, Giordano C. Defilippi C, et al. Angew Chem Int Ed Engl. 2019 Oct 21;58(43):15464-15470. doi: 10.1002/anie.201908758. Epub 2019 Sep 20. Angew Chem Int Ed Engl. 2019. PMID: 31437350 Review.
The HfN sample, in particular, showed the highest activity, requiring an overpotential of only 358 mV at 10 mA cm(-2) in Fe-free electrolyte and, above all, exhibiting long-term stability. This result places this system amongst one of the most promising catalysts for OER t …
The HfN sample, in particular, showed the highest activity, requiring an overpotential of only 358 mV at 10 mA cm(-2) in Fe-free electrolyte …
Relation of Dietary Sodium Intake With Subclinical Markers of Cardiovascular Disease (from MESA).
Kapoor K, Fashanu O, Post WS, Lutsey PL, Michos ED, deFilippi CR, McEvoy JW. Kapoor K, et al. Among authors: defilippi cr. Am J Cardiol. 2019 Aug 15;124(4):636-643. doi: 10.1016/j.amjcard.2019.05.014. Epub 2019 May 29. Am J Cardiol. 2019. PMID: 31300201 Free PMC article.
In conclusion, temporal shifts in the association between increased ESI and markers of subclinical CVD, hs-cTnT in the short term and NT-proBNP in the longer term, point to the complex pathobiology of the association between sodium intake and CVD. ...
In conclusion, temporal shifts in the association between increased ESI and markers of subclinical CVD, hs-cTnT in the short term and …
Copeptin to rule out myocardial infarction in Blacks versus Caucasians.
Beri N, Daniels LB, Jaffe A, Mueller C, Anand I, Peacock WF, Hollander JE, DeFilippi C, Schreiber D, McCord J, Limkakeng AT, Wu AHB, Apple FS, Diercks DB, Nagurney JT, Nowak RM, Cannon CM, Clopton P, Neath SX, Christenson RH, Hogan C, Vilke G, Maisel A. Beri N, et al. Among authors: defilippi c. Eur Heart J Acute Cardiovasc Care. 2019 Aug;8(5):395-403. doi: 10.1177/2048872618772500. Epub 2018 May 8. Eur Heart J Acute Cardiovasc Care. 2019. PMID: 29737180 Clinical Trial.
After controlling for age, hypertension, heart failure, chronic kidney disease and body mass index in a logistic regression model, the interaction term had a P value of 0.03. A cut-off of 6 pmol/l showed similar sensitivity in Caucasians as 14 pmol/l in Blacks. ...
After controlling for age, hypertension, heart failure, chronic kidney disease and body mass index in a logistic regression model, the inter …
Interpreting Cardiac Biomarkers in the Setting of Chronic Kidney Disease.
deFilippi CR, Herzog CA. deFilippi CR, et al. Clin Chem. 2017 Jan;63(1):59-65. doi: 10.1373/clinchem.2016.254748. Epub 2016 Nov 3. Clin Chem. 2017. PMID: 27811207 Review.
Last, we consider the caveats of interpreting natriuretic peptide results for the diagnosis of acute decompensated heart failure in addition to the short- and long-term prognostic implications of increased natriuretic peptide concentrations and CKD in a patient with heart …
Last, we consider the caveats of interpreting natriuretic peptide results for the diagnosis of acute decompensated heart failure in addition …
32 results