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Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients: 5-Year Outcomes of the SURTAVI Randomized Clinical Trial.
Van Mieghem NM, Deeb GM, Søndergaard L, Grube E, Windecker S, Gada H, Mumtaz M, Olsen PS, Heiser JC, Merhi W, Kleiman NS, Chetcuti SJ, Gleason TG, Lee JS, Cheng W, Makkar RR, Crestanello J, George B, George I, Kodali S, Yakubov SJ, Serruys PW, Lange R, Piazza N, Williams MR, Oh JK, Adams DH, Li S, Reardon MJ; SURTAVI Trial Investigators. Van Mieghem NM, et al. JAMA Cardiol. 2022 Oct 1;7(10):1000-1008. doi: 10.1001/jamacardio.2022.2695. JAMA Cardiol. 2022. PMID: 36001335 Free PMC article. Clinical Trial.

At 5 years, the rates of death or disabling stroke were similar (TAVR, 31.3% vs surgery, 30.8%; hazard ratio, 1.02 [95% CI, 0.85-1.22]; P = .85). Transprosthetic gradients remained lower (mean [SD], 8.6 [5.5] mm Hg vs 11.2 [6.0] mm Hg; P < .001) and aortic valve

…
At 5 years, the rates of death or disabling stroke were similar (TAVR, 31.3% vs surgery, 30.8%; hazard ratio, 1.02 [95% CI, 0.85-1.22]; P …
Expanded clinical use of everolimus eluting bioresorbable vascular scaffolds for treatment of coronary artery disease.
Diletti R, Ishibashi Y, Felix C, Onuma Y, Nakatani S, van Mieghem NM, Regar E, Valgimigli M, de Jaegere PP, van Ditzhuijzen N, Fam JM, Ligthart JMR, Lenzen MJ, Serruys PW, Zijlstra F, Jan van Geuns R. Diletti R, et al. Catheter Cardiovasc Interv. 2017 Jul;90(1):58-69. doi: 10.1002/ccd.26832. Epub 2016 Nov 29. Catheter Cardiovasc Interv. 2017. PMID: 27896897
Comparable results were observed among severe, moderate and noncalcified lesions in term of %diameter stenosis (%DS) (20.3 10.5%, 17.8 7.7%, 16.8 8.6%; P = 0.112) and acute gain (1.36 0.41 mm, 1.48 0.44 mm, 1.56 0.54 mm; P = 0.109). ...After BVS implantation …
Comparable results were observed among severe, moderate and noncalcified lesions in term of %diameter stenosis (%DS) (20.3 10.5%, 17. …
Randomized comparison of coronary stent implantation under ultrasound or angiographic guidance to reduce stent restenosis (OPTICUS Study).
Mudra H, di Mario C, de Jaegere P, Figulla HR, Macaya C, Zahn R, Wennerblom B, Rutsch W, Voudris V, Regar E, Henneke KH, Schächinger V, Zeiher A; OPTICUS (OPTimization with ICUS to reduce stent restenosis) Study Investigators. Mudra H, et al. Circulation. 2001 Sep 18;104(12):1343-9. doi: 10.1161/hc3701.096064. Circulation. 2001. PMID: 11560848 Clinical Trial.
At 6 months, repeat angiography revealed no significant differences between the groups with ultrasound- or angiography-guided stent implantation with respect to dichotomous restenosis rate (24.5% versus 22.8%, P=0.68), minimal lumen diameter (1.95+/-0.72 mm versus 1.91+/-0 …
At 6 months, repeat angiography revealed no significant differences between the groups with ultrasound- or angiography-guided stent implanta …
Colombian experience with transcatheter aortic valve implantation of medtronic CoreValve.
Dager AE, Nuis RJ, Caicedo B, Fonseca JA, Arana C, Cruz L, Benitez LM, Nader CA, Duenas E, de Marchena EJ, O'Neill WW, de Jaegere PP. Dager AE, et al. Tex Heart Inst J. 2012;39(3):351-8. Tex Heart Inst J. 2012. PMID: 22719143 Free PMC article.
Mean peak transvalvular gradient decreased from 74 29 to 17 8 mmHg and mean transvalvular gradient from 40 17 to 8 4 mmHg (both P=0.001). Moderate or severe aortic regurgitation decreased from 32% to 18% (P=0.12) and mitral regurgitation from 32% to 13% (P=0. …
Mean peak transvalvular gradient decreased from 74 29 to 17 8 mmHg and mean transvalvular gradient from 40 17 to 8 4 mmHg (both P=0.0 …
Prevalence, factors associated with, and prognostic effects of preoperative anemia on short- and long-term mortality in patients undergoing transcatheter aortic valve implantation.
Nuis RJ, Sinning JM, Rodés-Cabau J, Gotzmann M, van Garsse L, Kefer J, Bosmans J, Yong G, Dager AE, Revilla-Orodea A, Urena M, Nickenig G, Werner N, Maessen J, Astarci P, Perez S, Benitez LM, Amat-Santos IJ, López J, Dumont E, van Mieghem N, van Gelder T, van Domburg RT, de Jaegere PP. Nuis RJ, et al. Circ Cardiovasc Interv. 2013 Dec;6(6):625-34. doi: 10.1161/CIRCINTERVENTIONS.113.000409. Epub 2013 Nov 26. Circ Cardiovasc Interv. 2013. PMID: 24280965
In multivariable analyses, preoperative anemia was not associated with 30-day mortality (1.72 [0.96-3.12]; P=0.073) but showed the strongest association with 1-year mortality with a hazard ratio (95% confidence interval) of 2.78 (1.60-4.82) in patients with hemoglobin < …
In multivariable analyses, preoperative anemia was not associated with 30-day mortality (1.72 [0.96-3.12]; P=0.073) but showed the st …
Three-year clinical follow-up of the unrestricted use of sirolimus-eluting stents as part of the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
Daemen J, Ong AT, Stefanini GG, Tsuchida K, Spindler H, Sianos G, de Jaegere PP, van Domburg RT, Serruys PW. Daemen J, et al. Am J Cardiol. 2006 Oct 1;98(7):895-901. doi: 10.1016/j.amjcard.2006.04.031. Epub 2006 Aug 7. Am J Cardiol. 2006. PMID: 16996869
Sirolimus-eluting stents (SESs) have been shown to decrease restenosis compared with bare metal stents (BMSs). Currently, there are limited data on the long-term efficacy of these devices in a real-world patient population. ...After 3 years, the cumulative incidence of maj …
Sirolimus-eluting stents (SESs) have been shown to decrease restenosis compared with bare metal stents (BMSs). Currently, there are limited …