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The first MASH drug therapy on the horizon: Current perspectives of resmetirom.
Petta S, Targher G, Romeo S, Pajvani UB, Zheng MH, Aghemo A, Valenti LVC. Petta S, et al. Among authors: zheng mh. Liver Int. 2024 Apr 5. doi: 10.1111/liv.15930. Online ahead of print. Liver Int. 2024. PMID: 38578141 Review.
The safety profile of resmetirom appears acceptable, with gastrointestinal adverse events being the most common, though generally mild or moderate. However, long-term surveillance is warranted to monitor for potential risks related to thyroid, gonadal, or bone diseases. .. …
The safety profile of resmetirom appears acceptable, with gastrointestinal adverse events being the most common, though generally mild or mo …
Comparison of a novel hand-held retractor-assisted transforaminal lumbar interbody fusion by the wiltse approach and posterior TLIF: a one-year prospective controlled study.
Shen X, Li FT, Quan Cheng Y, Zheng MH, Yao XQ, Wang HM, Ting Chen J, Jiang H. Shen X, et al. Among authors: zheng mh. BMC Musculoskelet Disord. 2024 Feb 14;25(1):142. doi: 10.1186/s12891-024-07248-w. BMC Musculoskelet Disord. 2024. PMID: 38355528 Free PMC article.
CONCLUSION: Our study showed that this novel hand-held retractor system assisted Wiltse approach TLIF can significantly reduce paraspinal muscle injury, postoperative drainage, and intraoperative blood loss, mobilization and discharge time, as well as yield better short-term …
CONCLUSION: Our study showed that this novel hand-held retractor system assisted Wiltse approach TLIF can significantly reduce paraspinal mu …
Global survey of stigma among physicians and patients with nonalcoholic fatty liver disease.
Younossi ZM, Alqahtani SA, Alswat K, Yilmaz Y, Keklikkiran C, Funuyet-Salas J, Romero-Gómez M, Fan JG, Zheng MH, El-Kassas M, Castera L, Liu CJ, Wai-Sun Wong V, Zelber-Sagi S, Allen AM, Lam B, Treeprasertsuk S, Hameed S, Takahashi H, Kawaguchi T, Schattenberg JM, Duseja A, Newsome PN, Francque S, Spearman CW, Castellanos Fernández MI, Burra P, Roberts SK, Chan WK, Arrese M, Silva M, Rinella M, Singal AK, Gordon S, Fuchs M, Alkhouri N, Cusi K, Loomba R, Ranagan J, Eskridge W, Kautz A, Ong JP, Kugelmas M, Eguchi Y, Diago M, Yu ML, Gerber L, Fornaresio L, Nader F, Henry L, Racila A, Golabi P, Stepanova M, Carrieri P, Lazarus JV; Global NASH Council. Younossi ZM, et al. Among authors: zheng mh. J Hepatol. 2024 Mar;80(3):419-430. doi: 10.1016/j.jhep.2023.11.004. Epub 2023 Nov 18. J Hepatol. 2024. PMID: 37984709
Of all patients, 48% ever disclosed having NAFLD/NASH to family/friends; the most commonly used term was "fatty liver" (88% at least sometimes); "metabolic disease" or "MAFLD" were rarely used (never by >84%). ...The most popular response was being neither comfortable n …
Of all patients, 48% ever disclosed having NAFLD/NASH to family/friends; the most commonly used term was "fatty liver" (88% at least …
An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease.
Sun DQ, Targher G, Byrne CD, Wheeler DC, Wong VW, Fan JG, Tilg H, Yuan WJ, Wanner C, Gao X, Long MT, Kanbay M, Nguyen MH, Navaneethan SD, Yilmaz Y, Huang Y, Gani RA, Marzuillo P, Boursier J, Zhang H, Jung CY, Chai J, Valenti L, Papatheodoridis G, Musso G, Wong YJ, El-Kassas M, Méndez-Sánchez N, Sookoian S, Pavlides M, Duseja A, Holleboom AG, Shi J, Chan WK, Fouad Y, Yang J, Treeprasertsuk S, Cortez-Pinto H, Hamaguchi M, Romero-Gomez M, Al Mahtab M, Ocama P, Nakajima A, Dai C, Eslam M, Wei L, George J, Zheng MH. Sun DQ, et al. Among authors: zheng mh. Hepatobiliary Surg Nutr. 2023 Jun 1;12(3):386-403. doi: 10.21037/hbsn-22-421. Epub 2023 Feb 23. Hepatobiliary Surg Nutr. 2023. PMID: 37351121 Free PMC article. Review.
BACKGROUND: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-a …
BACKGROUND: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver …
An international multidisciplinary consensus statement on MAFLD and the risk of CVD.
Zhou XD, Targher G, Byrne CD, Somers V, Kim SU, Chahal CAA, Wong VW, Cai J, Shapiro MD, Eslam M, Steg PG, Sung KC, Misra A, Li JJ, Brotons C, Huang Y, Papatheodoridis GV, Sun A, Yilmaz Y, Chan WK, Huang H, Méndez-Sánchez N, Alqahtani SA, Cortez-Pinto H, Lip GYH, de Knegt RJ, Ocama P, Romero-Gomez M, Fudim M, Sebastiani G, Son JW, Ryan JD, Ikonomidis I, Treeprasertsuk S, Pastori D, Lupsor-Platon M, Tilg H, Ghazinyan H, Boursier J, Hamaguchi M, Nguyen MH, Fan JG, Goh GB, Al Mahtab M, Hamid S, Perera N, George J, Zheng MH. Zhou XD, et al. Among authors: zheng mh. Hepatol Int. 2023 Aug;17(4):773-791. doi: 10.1007/s12072-023-10543-8. Epub 2023 May 19. Hepatol Int. 2023. PMID: 37204656 Free PMC article.
Since systemic metabolic dysfunction underlies its pathogenesis, the term metabolic (dysfunction)-associated fatty liver disease (MAFLD) has been proposed for this condition. ...
Since systemic metabolic dysfunction underlies its pathogenesis, the term metabolic (dysfunction)-associated fatty liver disease (MAF …
[Clinical characteristics and placental pathology analysis of 14 cases of pregnancy with aortic dissection/aortic aneurysm].
Zheng MH, Chen D, Shang JF, Liu R, Zhou HT. Zheng MH, et al. Zhonghua Bing Li Xue Za Zhi. 2023 May 8;52(5):480-485. doi: 10.3760/cma.j.cn112151-20230129-00078. Zhonghua Bing Li Xue Za Zhi. 2023. PMID: 37106290 Chinese.
Four of the pregnant women underwent aortic dissection surgery after caesarean section, three underwent caesarean section after aortic dissection surgery, and seven underwent both caesarean section and aortic dissection procedures. Among the newborns, 2 cases were full-term …
Four of the pregnant women underwent aortic dissection surgery after caesarean section, three underwent caesarean section after aortic disse …
Additively manufactured polyethylene terephthalate scaffolds for scapholunate interosseous ligament reconstruction.
Gomez-Cerezo MN, Perevoshchikova N, Ruan R, Moerman KM, Bindra R, Lloyd DG, Zheng MH, Saxby DJ, Vaquette C. Gomez-Cerezo MN, et al. Among authors: zheng mh. Biomater Adv. 2023 Jun;149:213397. doi: 10.1016/j.bioadv.2023.213397. Epub 2023 Mar 21. Biomater Adv. 2023. PMID: 37023566
In conclusion, the PET scaffold presented several promising characteristics for the immediate mechanical stabilisation of disassociated scaphoid and lunate and, in the longer-term, the regeneration of the ruptured SLIL....
In conclusion, the PET scaffold presented several promising characteristics for the immediate mechanical stabilisation of disassociated scap …
Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study.
Wu YL, Lin ZJ, Li CC, Lin X, Shan SK, Guo B, Zheng MH, Li F, Yuan LQ, Li ZH. Wu YL, et al. Among authors: zheng mh. Signal Transduct Target Ther. 2023 Mar 2;8(1):98. doi: 10.1038/s41392-023-01333-7. Signal Transduct Target Ther. 2023. PMID: 36864020 Free PMC article. Review.
Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease (NAFLD), osteoporosis, gout, hyperthyroidism, hypothyroidism and others. The term 'epigenet …
Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases, such as diabetes, o …
65 results