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Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with reductions in microbial richness and diversity in persons with cystic fibrosis.
Sci Rep. 2023 Jan 21;13(1):1217. doi: 10.1038/s41598-023-27628-x.
Sci Rep. 2023.
PMID: 36681756
Free PMC article.
While higher microbial diversity is associated with higher lung function, the data on the impact of short-term antibiotics on changes in microbial diversity is conflicting. ...
While higher microbial diversity is associated with higher lung function, the data on the impact of short-term antibiotics on changes …
Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis.
Hahn A, Fanous H, Jensen C, Chaney H, Sami I, Perez GF, Koumbourlis AC, Louie S, Bost JE, van den Anker JN, Freishtat RJ, Zemanick ET, Crandall KA.
Hahn A, et al. Among authors: zemanick et.
Sci Rep. 2019 Feb 22;9(1):2534. doi: 10.1038/s41598-019-38984-y.
Sci Rep. 2019.
PMID: 30796252
Free PMC article.
In persons with cystic fibrosis (CF), decreased airway microbial diversity is associated with lower lung function. Conflicting data exist on the impact of short-term antibiotics for treatment of acute pulmonary exacerbations. ...
In persons with cystic fibrosis (CF), decreased airway microbial diversity is associated with lower lung function. Conflicting data exist on …
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