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House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies.
Fessler MB, Carnes MU, Salo PM, Wilkerson J, Cohn RD, King D, Hoppin JA, Sandler DP, Travlos G, London SJ, Thorne PS, Zeldin DC. Fessler MB, et al. Among authors: zeldin dc. Environ Health Perspect. 2017 May 31;125(5):057010. doi: 10.1289/EHP661. Environ Health Perspect. 2017. PMID: 28599265 Free PMC article.
In the ALHS, we tested for a gene [Toll-like Receptor 4 (TLR4), encoding the endotoxin receptor]-by-environment interaction in the endotoxin-leukocyte relationship using regression models with an interaction term. RESULTS: There is a statistically significant, positive ass …
In the ALHS, we tested for a gene [Toll-like Receptor 4 (TLR4), encoding the endotoxin receptor]-by-environment interaction in the endotoxin …
Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide.
Xiao B, Li X, Yan J, Yu X, Yang G, Xiao X, Voltz JW, Zeldin DC, Wang DW. Xiao B, et al. Among authors: zeldin dc. J Pharmacol Exp Ther. 2010 Sep 1;334(3):784-94. doi: 10.1124/jpet.110.167510. Epub 2010 May 25. J Pharmacol Exp Ther. 2010. PMID: 20501636 Free PMC article.
The study sought to determine the improvement of hypertension and cardiac function by overexpressing P450 epoxygenases in vivo. Long-term expression of CYP102 F87V or CYP2J2 in spontaneously hypertensive rats (SHR) was mediated by using a type 8 recombinant adeno-associate …
The study sought to determine the improvement of hypertension and cardiac function by overexpressing P450 epoxygenases in vivo. Long-term …
Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways.
Yuan G, Deng J, Wang T, Zhao C, Xu X, Wang P, Voltz JW, Edin ML, Xiao X, Chao L, Chao J, Zhang XA, Zeldin DC, Wang DW. Yuan G, et al. Among authors: zeldin dc. Endocrinology. 2007 May;148(5):2016-26. doi: 10.1210/en.2006-0602. Epub 2007 Feb 1. Endocrinology. 2007. PMID: 17272402 Free PMC article.
In the current study, we evaluated the potential of a recombinant adeno-associated viral vector expressing the HK cDNA (rAAV-HK) as a sole, long-term therapy to correct insulin resistance and prevent renal damage in streptozotocin-induced type-2 diabetic rats. Administrati …
In the current study, we evaluated the potential of a recombinant adeno-associated viral vector expressing the HK cDNA (rAAV-HK) as a sole, …
Induction of cardiac cytochrome p450 in cocaine-treated mice.
Wang JF, Yang Y, Sullivan MF, Min J, Cai J, Zeldin DC, Xiao YF, Morgan JP. Wang JF, et al. Among authors: zeldin dc. Exp Biol Med (Maywood). 2002 Mar;227(3):182-8. doi: 10.1177/153537020222700305. Exp Biol Med (Maywood). 2002. PMID: 11856816
Tumor necrosis factor-alpha (TNF-alpha) content and creatine phosphokinase (CPK) activity in mice hearts and serums were significantly increased after long-term treatment with cocaine. Pretreatment with the P450 inhibitor, cimetidine (Cime, 50 mg/kg) or metyrapone (Mety, 4 …
Tumor necrosis factor-alpha (TNF-alpha) content and creatine phosphokinase (CPK) activity in mice hearts and serums were significantly incre …