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Changing global epidemiology of chronic hepatitis C virus-related outcomes from 2010 to 2019: cirrhosis is the growing burden of hepatitis C virus-related disease.
Pham YT, Huang DQ, Zhang Z, Ng CH, Tan DJH, Nguyen HC, Nguyen TC, Behari J, Yuan JM, Luu HN. Pham YT, et al. Among authors: yuan jm. Eur J Cancer Prev. 2024 Mar 22. doi: 10.1097/CEJ.0000000000000885. Online ahead of print. Eur J Cancer Prev. 2024. PMID: 38568179
BACKGROUND: Chronic infection with hepatitis C virus (HCV) has a long-term impact on hepatic consequences. A comprehensive evaluation of the global burden of HCV-related health outcomes can help to develop a global HCV prevention and treatment program. ...
BACKGROUND: Chronic infection with hepatitis C virus (HCV) has a long-term impact on hepatic consequences. A comprehensive evaluation …
Pulmonary circulatory system characteristics are associated with future lung cancer risk.
Pu J, Bandos A, Yu T, Wang R, Yuan JM, Herman J, Wilson D. Pu J, et al. Among authors: yuan jm. Med Phys. 2024 Apr;51(4):2589-2597. doi: 10.1002/mp.16930. Epub 2023 Dec 30. Med Phys. 2024. PMID: 38159298
These factors significantly improve prognostication based on demographic factors and noncirculatory patient characteristics, particularly in the long term. Approximately 10% of the population can be identified with risk several times greater than average....
These factors significantly improve prognostication based on demographic factors and noncirculatory patient characteristics, particularly in …
Lung Cancer Risk Prediction Models for Asian Ever-Smokers.
Yang JJ, Wen W, Zahed H, Zheng W, Lan Q, Abe SK, Rahman MS, Islam MR, Saito E, Gupta PC, Tamakoshi A, Koh WP, Gao YT, Sakata R, Tsuji I, Malekzadeh R, Sugawara Y, Kim J, Ito H, Nagata C, You SL, Park SK, Yuan JM, Shin MH, Kweon SS, Yi SW, Pednekar MS, Kimura T, Cai H, Lu Y, Etemadi A, Kanemura S, Wada K, Chen CJ, Shin A, Wang R, Ahn YO, Shin MH, Ohrr H, Sheikh M, Blechter B, Ahsan H, Boffetta P, Chia KS, Matsuo K, Qiao YL, Rothman N, Inoue M, Kang D, Robbins HA, Shu XO. Yang JJ, et al. Among authors: yuan jm. J Thorac Oncol. 2024 Mar;19(3):451-464. doi: 10.1016/j.jtho.2023.11.002. Epub 2023 Nov 7. J Thorac Oncol. 2024. PMID: 37944700
The Shanghai models were found to have marginal improvement overall in discrimination (AUC [95% CI] = 0.72 [0.69-0.74] for lung cancer death and 0.70 [0.67-0.72] for lung cancer incidence) but consistently outperformed the selected Western models among low-intensity smokers and l …
The Shanghai models were found to have marginal improvement overall in discrimination (AUC [95% CI] = 0.72 [0.69-0.74] for lung cancer death …
Soluble CD137 and risk of hepatocellular carcinoma: nested case-control studies in cohorts in Shanghai and Singapore.
Thomas CE, Adibi JJ, Kuipers AL, Diergaarde B, Luu HN, Jin A, Koh WP, Gao YT, Adams-Haduch J, Wang R, Lokshin A, Behari J, Yuan JM. Thomas CE, et al. Among authors: yuan jm. Br J Cancer. 2023 Jun;128(11):2081-2088. doi: 10.1038/s41416-023-02223-z. Epub 2023 Mar 28. Br J Cancer. 2023. PMID: 36977826 Free PMC article.
CONCLUSION: sCD137 was associated with higher risk of HCC in two studies nested in general population cohorts. sCD137 may be a long-term risk marker of HCC development....
CONCLUSION: sCD137 was associated with higher risk of HCC in two studies nested in general population cohorts. sCD137 may be a long-term …
Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study.
Wang Z, Budhu AS, Shen Y, Wong LL, Hernandez BY, Tiirikainen M, Ma X, Irwin ML, Lu L, Zhao H, Lim JK, Taddei T, Mishra L, Pawlish K, Stroup A, Brown R, Nguyen MH, Koshiol J, Hernandez MO, Forgues M, Yang HI, Lee MH, Huang YH, Iwasaki M, Goto A, Suzuki S, Matsuda K, Tanikawa C, Kamatani Y, Mann D, Guarnera M, Shetty K, Thomas CE, Yuan JM, Khor CC, Koh WP, Risch H, Wang XW, Yu H. Wang Z, et al. Among authors: yuan jm. JGH Open. 2021 Nov 27;5(12):1363-1372. doi: 10.1002/jgh3.12682. eCollection 2021 Dec. JGH Open. 2021. PMID: 34950780 Free PMC article.
BACKGROUND AND AIM: Chronic hepatitis C virus (HCV) infection, long-term alcohol use, cigarette smoking, and obesity are the major risk factors for hepatocellular carcinoma (HCC) in the United States, but the disease risk varies substantially among individuals with these f …
BACKGROUND AND AIM: Chronic hepatitis C virus (HCV) infection, long-term alcohol use, cigarette smoking, and obesity are the major ri …
Dynamics of hepatic steatosis resolution and changes in gut microbiome with weight loss in nonalcoholic fatty liver disease.
Behari J, Graham L, Wang R, Schirda C, Borhani AA, Methé BA, Li K, Morris A, Luu HN, Palmieri S, Yuan JM. Behari J, et al. Among authors: yuan jm. Obes Sci Pract. 2021 Jan 4;7(2):217-225. doi: 10.1002/osp4.476. eCollection 2021 Apr. Obes Sci Pract. 2021. PMID: 33841891 Free PMC article.
Further research is warranted to understand the effects of intensive weight loss and gut microbiome changes on long-term NAFLD resolution....
Further research is warranted to understand the effects of intensive weight loss and gut microbiome changes on long-term NAFLD resolu …
Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population.
Chang X, Dorajoo R, Sun Y, Wang L, Ong CN, Liu J, Khor CC, Yuan JM, Koh WP, Friedlander Y, Heng CK. Chang X, et al. Among authors: yuan jm. Nutr J. 2020 Oct 30;19(1):119. doi: 10.1186/s12937-020-00626-9. Nutr J. 2020. PMID: 33126880 Free PMC article.
The interaction between plasma PUFAs and genetic variants was assessed by introducing an additional term (PUFAgenetic variant) in the regression model. Analysis was carried out in cases and controls separately and subsequently meta-analyzed using the inverse-variance weigh …
The interaction between plasma PUFAs and genetic variants was assessed by introducing an additional term (PUFAgenetic variant) in the …
Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population.
Chang X, Dorajoo R, Han Y, Wang L, Liu J, Khor CC, Low AF, Chan MY, Yuan JM, Koh WP, Friedlander Y, Heng CK. Chang X, et al. Among authors: yuan jm. Mol Genet Genomic Med. 2020 Oct;8(10):e1450. doi: 10.1002/mgg3.1450. Epub 2020 Aug 13. Mol Genet Genomic Med. 2020. PMID: 32794371 Free PMC article.
Interaction analyses were performed by introducing an interaction term in the same regression models. RESULTS: Although rs217181 was not significantly associated with CAD severity and cardiovascular mortality (excluding stroke) in all subjects, when stratified by hypertens …
Interaction analyses were performed by introducing an interaction term in the same regression models. RESULTS: Although rs217181 was …
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de Las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR, Guo X, Manning A, Chasman DI, Aschard H, Bartz TM, Bielak LF, Campbell A, Cheng CY, Dorajoo R, Hartwig FP, Horimoto ARVR, Li C, Li-Gao R, Liu Y, Marten J, Musani SK, Ntalla I, Rankinen T, Richard M, Sim X, Smith AV, Tajuddin SM, Tayo BO, Vojinovic D, Warren HR, Xuan D, Alver M, Boissel M, Chai JF, Chen X, Christensen K, Divers J, Evangelou E, Gao C, Girotto G, Harris SE, He M, Hsu FC, Kühnel B, Laguzzi F, Li X, Lyytikäinen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Rueedi R, Shu XO, Snieder H, Sofer T, Takeuchi F, Verweij N, Ware EB, Weiss S, Yanek LR, Amin N, Arking DE, Arnett DK, Bergmann S, Boerwinkle E, Brody JA, Broeckel U, Brumat M, Burke G, Cabrera CP, Canouil M, Chee ML, Chen YI, Cocca M, Connell J, de Silva HJ, de Vries PS, Eiriksdottir G, Faul JD, Fisher V, Forrester T, Fox EF, Friedlander Y, Gao H, Gigante B, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt S, Ikram MA, Irvin MR, Kähönen M, Kavousi M, Khor CC, Kilpeläinen TO, Koh WP, Komulainen P, Kraja AT, Krieger JE, Langefeld CD, Li Y, Liang J, Liewald DCM, Liu CT, Liu J, Lohman KK, Mägi R, McKenzie … See abstract for full author list ➔ de Las Fuentes L, et al. Among authors: yuan jm. Mol Psychiatry. 2021 Jun;26(6):2111-2125. doi: 10.1038/s41380-020-0719-3. Epub 2020 May 5. Mol Psychiatry. 2021. PMID: 32372009 Free PMC article.
Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction effects. Analyses were performed for systolic BP, diastolic BP, mean arterial pressure, and pulse pressure. ...
Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction ef …
Handgrip Strength and Timed Up-and-Go (TUG) Test are Predictors of Short-Term Mortality among Elderly in a Population-Based Cohort in Singapore.
Chua KY, Lim WS, Lin X, Yuan JM, Koh WP. Chua KY, et al. Among authors: yuan jm. J Nutr Health Aging. 2020;24(4):371-378. doi: 10.1007/s12603-020-1337-0. J Nutr Health Aging. 2020. PMID: 32242204 Free article.
OBJECTIVES: Asian studies on how physical tests predict short-term mortality in elderly are scarce. We assessed handgrip strength and timed-up-and-go (TUG) as such predictors among elderly Chinese in Singapore. ...CONCLUSION: Among elderly in a Chinese population, handgrip …
OBJECTIVES: Asian studies on how physical tests predict short-term mortality in elderly are scarce. We assessed handgrip strength and …
34 results