mTOR signaling promotes rapid m6A mRNA methylation to regulate NK-cell activation and effector functions.
Meng M, Zhong Z, Song L, Zhang Z, Yin X, Xie X, Tian L, Wu W, Yang Y, Deng Y, Peng H, Wu S, Ran G, Lin Y, Lai Q, Bi Q, Yan F, Ji Y, Wang Y, Li X, Yi P, Yu J, Deng Y.
Meng M, et al. Among authors: yu j.
Cancer Immunol Res. 2024 Apr 19. doi: 10.1158/2326-6066.CIR-23-0339. Online ahead of print.
Cancer Immunol Res. 2024.
PMID: 38640466
In this study, we discovered that NK-cell N6-methyladenosine (m6A) methylation levels were rapidly upregulated upon short-term NK-cell activation and were repressed in the tumor microenvironment. ...
In this study, we discovered that NK-cell N6-methyladenosine (m6A) methylation levels were rapidly upregulated upon short-term NK-cel …