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Synaptically-targeted long non-coding RNA SLAMR promotes structural plasticity by increasing translation and CaMKII activity.
Espadas I, Wingfield JL, Nakahata Y, Chanda K, Grinman E, Ghosh I, Bauer KE, Raveendra B, Kiebler MA, Yasuda R, Rangaraju V, Puthanveettil S. Espadas I, et al. Among authors: yasuda r. Nat Commun. 2024 Mar 27;15(1):2694. doi: 10.1038/s41467-024-46972-8. Nat Commun. 2024. PMID: 38538603 Free PMC article.
However, it remains largely unknown whether and how neuronal activity impacts the transcriptional regulation of lncRNAs, or if this leads to synapse-related changes and contributes to the formation of long-term memories. Here, we report the identification of a lncRNA, SLAM …
However, it remains largely unknown whether and how neuronal activity impacts the transcriptional regulation of lncRNAs, or if this leads to …
BDNF signaling requires Matrix Metalloproteinase-9 during structural synaptic plasticity.
Legutko D, Kuźniewska B, Kalita K, Yasuda R, Kaczmarek L, Michaluk P. Legutko D, et al. Among authors: yasuda r. bioRxiv [Preprint]. 2024 Jan 30:2023.12.08.569797. doi: 10.1101/2023.12.08.569797. bioRxiv. 2024. PMID: 38106209 Free PMC article. Preprint.
Synaptic plasticity underlies learning and memory processes as well as contributes, in its aberrant form, to neuropsychiatric disorders. One of its major forms is structural long-term potentiation (sLTP), an activity-dependent growth of dendritic spines that harbor excitat …
Synaptic plasticity underlies learning and memory processes as well as contributes, in its aberrant form, to neuropsychiatric disorders. One …
Clinicopathologic Features, Genetics, Treatment, and Long-Term Outcomes in Japanese Children and Young Adults with Benign Recurrent Intrahepatic Cholestasis: A Multicenter Study.
Kato K, Umetsu S, Togawa T, Ito K, Kawabata T, Arinaga-Hino T, Tsumura N, Yasuda R, Mihara Y, Kusano H, Ito S, Imagawa K, Hayashi H, Inui A, Yamashita Y, Mizuochi T. Kato K, et al. Among authors: yasuda r. J Clin Med. 2023 Sep 15;12(18):5979. doi: 10.3390/jcm12185979. J Clin Med. 2023. PMID: 37762919 Free PMC article.
No patient developed cirrhosis; most had normal growth and development. The long-term outcomes were satisfactory....
No patient developed cirrhosis; most had normal growth and development. The long-term outcomes were satisfactory....
SLAMR, a synaptically targeted lncRNA, facilitates the consolidation of contextual fear memory.
Espadas I, Wingfield J, Grinman E, Ghosh I, Chanda K, Nakahata Y, Bauer K, Raveendra B, Kiebler M, Yasuda R, Rangaraju V, Puthanveettil S. Espadas I, et al. Among authors: yasuda r. Res Sq [Preprint]. 2023 Mar 14:rs.3.rs-2489387. doi: 10.21203/rs.3.rs-2489387/v1. Res Sq. 2023. PMID: 36993323 Free PMC article. Updated. Preprint.
However, it remains largely unknown whether and how the transcriptional regulation of long noncoding RNAs results in activity-dependent changes at the synapse and facilitate formation of long-term memories. Here, we report the identification of a novel lncRNA, SLAMR, that …
However, it remains largely unknown whether and how the transcriptional regulation of long noncoding RNAs results in activity-dependent chan …
Alcohol septal ablation versus surgical septal myectomy of obstructive hypertrophic cardiomyopathy: systematic review and meta-analysis.
Yokoyama Y, Shimoda T, Shimada YJ, Shimamura J, Akita K, Yasuda R, Takayama H, Kuno T. Yokoyama Y, et al. Among authors: yasuda r. Eur J Cardiothorac Surg. 2023 Mar 1;63(3):ezad043. doi: 10.1093/ejcts/ezad043. Eur J Cardiothorac Surg. 2023. PMID: 36782361
The subgroup analysis with follow-up 5 years revealed higher long-term mortality with ASA [HR (95% CI) 1.50 (1.04-2.15); P = 0.03; I2 = 52%]. ...
The subgroup analysis with follow-up 5 years revealed higher long-term mortality with ASA [HR (95% CI) 1.50 (1.04-2.15); P = 0.03; I2 …
A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality.
Ishinoda Y, Masaki N, Hitomi Y, Taruoka A, Kawai A, Iwashita M, Yumita Y, Kagami K, Yasuda R, Ido Y, Toya T, Ikegami Y, Namba T, Nagatomo Y, Miyazaki K, Takase B, Adachi T. Ishinoda Y, et al. Among authors: yasuda r. J Atheroscler Thromb. 2023 Oct 1;30(10):1364-1375. doi: 10.5551/jat.63779. Epub 2023 Feb 11. J Atheroscler Thromb. 2023. PMID: 36775332 Free PMC article.
AIMS: The long-term prognostic value of the bioavailability of L-arginine, an important source of nitric oxide for the maintenance of vascular endothelial function, has not been investigated fully. We therefore investigated the relationship between amino acid profile and l …
AIMS: The long-term prognostic value of the bioavailability of L-arginine, an important source of nitric oxide for the maintenance of …
Effects of New-Generation Antiepileptic Drug Prophylaxis on Delayed Neurovascular Events After Aneurysmal Subarachnoid Hemorrhage.
Suzuki H, Miura Y, Yasuda R, Yago T, Mizutani H, Ichikawa T, Miyazaki T, Kitano Y, Nishikawa H, Kawakita F, Fujimoto M, Toma N. Suzuki H, et al. Among authors: yasuda r. Transl Stroke Res. 2023 Dec;14(6):899-909. doi: 10.1007/s12975-022-01101-9. Epub 2022 Nov 5. Transl Stroke Res. 2023. PMID: 36333650
Prophylactic antiepileptic drugs differed depending on the study terms: none (2013 - 2015), levetiracetam for patients at high risks of seizures (2016 - 2019), and perampanel for all patients (2020 - 2021). The 3rd term had the lowest occurrence of delayed cerebral microin …
Prophylactic antiepileptic drugs differed depending on the study terms: none (2013 - 2015), levetiracetam for patients at high risks of seiz …
Posterior Communicating Artery-incorporated Internal Carotid-Posterior Communicating Artery Aneurysms Prone to Recur After Coil Embolization.
Yasuda R, Miura Y, Suzuki Y, Tsuji M, Shiba M, Toma N, Suzuki H. Yasuda R, et al. World Neurosurg. 2022 Jun;162:e546-e552. doi: 10.1016/j.wneu.2022.03.062. Epub 2022 Mar 18. World Neurosurg. 2022. PMID: 35314412
Aneurysms whose 3-dimensional images were available, whose initial treatment was performed during the study period, and whose follow-up term was more than 1 year were included. Information of the patients, the aneurysms and Pcoms, the initial treatment, and angiographic ou …
Aneurysms whose 3-dimensional images were available, whose initial treatment was performed during the study period, and whose follow-up t …
Effectiveness of the d-ROMs oxidative stress test to predict long-term cardiovascular mortality.
Hitomi Y, Masaki N, Ishinoda Y, Ido Y, Iwashita M, Yumita Y, Kagami K, Yasuda R, Ikegami Y, Toya T, Namba T, Nagatomo Y, Takase B, Adachi T. Hitomi Y, et al. Among authors: yasuda r. Int J Cardiol. 2022 May 1;354:43-47. doi: 10.1016/j.ijcard.2022.03.001. Epub 2022 Mar 4. Int J Cardiol. 2022. PMID: 35257723
BACKGROUND: The long-term prognostic value of the derivatives of reactive oxidative metabolites (d-ROMs) oxidative stress test, which measures hydroperoxide in blood, has not been fully investigated. ...CONCLUSION: A high d-ROMs value is an independent predictor of the lon …
BACKGROUND: The long-term prognostic value of the derivatives of reactive oxidative metabolites (d-ROMs) oxidative stress test, which …
46 results