Involvement of Toll-like receptor 4 in acetaminophen hepatotoxicity.
Yohe HC, O'Hara KA, Hunt JA, Kitzmiller TJ, Wood SG, Bement JL, Bement WJ, Szakacs JG, Wrighton SA, Jacobs JM, Kostrubsky V, Sinclair PR, Sinclair JF.
Yohe HC, et al. Among authors: wrighton sa.
Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1269-79. doi: 10.1152/ajpgi.00239.2005. Epub 2006 Jan 26.
Am J Physiol Gastrointest Liver Physiol. 2006.
PMID: 16439473
Free article.
Others have found that ethanol-mediated liver disease is decreased in C3H/HeJ mice, which have a mutated TLR4 resulting in a decreased response to endotoxin compared with endotoxin-responsive mice. In the present study, short-term (1 wk) pretreatment with ethanol plus isop …
Others have found that ethanol-mediated liver disease is decreased in C3H/HeJ mice, which have a mutated TLR4 resulting in a decreased respo …