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Increased demand for paramedic transports to the emergency department in Ontario, Canada: a population-level descriptive study from 2010 to 2019.
Strum RP, Drennan IR, Mowbray FI, Mondoux S, Worster A, Babe G, Costa AP. Strum RP, et al. Among authors: worster a. CJEM. 2022 Nov;24(7):742-750. doi: 10.1007/s43678-022-00363-4. Epub 2022 Aug 19. CJEM. 2022. PMID: 35984572 Free PMC article.
Our findings indicate a mounting need to develop innovative solutions to meet the increased demand on paramedic services and to implement long-term strategies across provincial paramedic systems....
Our findings indicate a mounting need to develop innovative solutions to meet the increased demand on paramedic services and to implement lo …
Cardiac Troponin Testing in Patients with COVID-19: A Strategy for Testing and Reporting Results.
Kavsak PA, Hammarsten O, Worster A, Smith SW, Apple FS. Kavsak PA, et al. Among authors: worster a. Clin Chem. 2021 Jan 8;67(1):107-113. doi: 10.1093/clinchem/hvaa225. Clin Chem. 2021. PMID: 33045044 Free PMC article. Review.
CONTENT: The purpose of this mini-review is: a) to review the pathophysiology of SARS-CoV-2 and the cardiovascular system, b) to overview the strengths and weaknesses of selected studies evaluating cardiac troponin in patients with COVID-19, and c) to recommend testing strategies …
CONTENT: The purpose of this mini-review is: a) to review the pathophysiology of SARS-CoV-2 and the cardiovascular system, b) to overview th …
Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.
Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S; COMPASS-MI Study Group. Neumann JT, et al. Among authors: worster a. N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377. N Engl J Med. 2019. PMID: 31242362
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lower likelihood of myocardial infarction and a lower short-term risk of cardiovascular events. For example, high-sensitivity troponin …
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lo …
Evaluation of the Siemens ADVIA Centaur high-sensitivity cardiac troponin I assay in serum.
Kavsak PA, Worster A, Hill SA, Jaffe AS. Kavsak PA, et al. Among authors: worster a. Clin Chim Acta. 2018 Dec;487:216-221. doi: 10.1016/j.cca.2018.10.012. Epub 2018 Oct 6. Clin Chim Acta. 2018. PMID: 30296440
We evaluated the Siemens ADVIA Centaur hs-cTnI assay in serum and thereby provide information on imprecision, long-term storage stability, freeze-thaw stability, method comparison to other hs-cTnI assays, and clinical performance. ...CONCLUSIONS: In serum, the Siemens ADVI …
We evaluated the Siemens ADVIA Centaur hs-cTnI assay in serum and thereby provide information on imprecision, long-term storage stabi …
Analytical comparison of three different versions of a high-sensitivity cardiac troponin I assay over 10years.
Kavsak PA, Worster A, Hill SA, MacRae AR, Jaffe AS. Kavsak PA, et al. Among authors: worster a. Clin Chim Acta. 2017 Dec;475:51-55. doi: 10.1016/j.cca.2017.10.006. Epub 2017 Oct 7. Clin Chim Acta. 2017. PMID: 29017768
BACKGROUND: Concerns have been raised on the long-term analytical performance of high-sensitivity cardiac troponin (hs-cTn) assays with respect to different reagent formulations, lots and instrumentation. ...
BACKGROUND: Concerns have been raised on the long-term analytical performance of high-sensitivity cardiac troponin (hs-cTn) assays wi …
Adverse outcomes associated with opioid prescription for acute low back pain: a systematic review protocol.
Mouravska N, Zielinski L, Bhatt M, Sanger N, Bawor M, Dennis B, Banfield L, MacKillop J, Paul J, Worster A, Laplante P, Thabane L, Samaan Z. Mouravska N, et al. Among authors: worster a. Syst Rev. 2017 Aug 14;6(1):163. doi: 10.1186/s13643-017-0556-x. Syst Rev. 2017. PMID: 28807047 Free PMC article.
There is a trend towards an increasing number of opioid prescriptions for ALBP despite the lack of investigation for its various short- and long-term outcomes. The objective of this review is to examine adverse outcomes associated with opioid use for ALBP. ...
There is a trend towards an increasing number of opioid prescriptions for ALBP despite the lack of investigation for its various short- and …
Do either corticosteroids or antiviral agents reduce the risk of long-term facial paresis in patients with new-onset Bell's palsy?
Worster A, Keim SM, Sahsi R, Pancioli AM; Best Evidence in Emergency Medicine (BEEM) Group. Worster A, et al. J Emerg Med. 2010 May;38(4):518-23. doi: 10.1016/j.jemermed.2009.08.016. Epub 2009 Oct 21. J Emerg Med. 2010. PMID: 19846267 Review.
BACKGROUND: The cause of Bell's palsy remains uncertain, although accumulating evidence suggests a viral etiology. To date, treatment to minimize long-term deficits from this disorder typically includes anti-inflammatory or antiviral medication. CLINICAL QUESTION: Do corti …
BACKGROUND: The cause of Bell's palsy remains uncertain, although accumulating evidence suggests a viral etiology. To date, treatment to min …
Does early intensive lowering of blood pressure reduce hematoma volume and improve clinical outcome after acute cerebral hemorrhage?
Worster A, Keim SM, Carpenter CR, Adeoye O; Best Evidence in Emergency Medicine (BEEM) Group. Worster A, et al. J Emerg Med. 2009 Nov;37(4):433-8. doi: 10.1016/j.jemermed.2009.05.002. Epub 2009 Jul 9. J Emerg Med. 2009. PMID: 19545967 Review.
RESULTS: The two randomized trials incorporated similar parallel designs and both trials measured clinical outcomes and short-term change in hematoma size. The smaller trial was only partially blinded and showed no difference in any of the outcomes; the large trial demonst …
RESULTS: The two randomized trials incorporated similar parallel designs and both trials measured clinical outcomes and short-term ch …
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