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Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy.
Duchesneau P, Besla R, Derouet MF, Guo L, Karoubi G, Silberberg A, Wong AP, Waddell TK. Duchesneau P, et al. Among authors: wong ap. Mol Ther. 2017 Mar 1;25(3):654-665. doi: 10.1016/j.ymthe.2016.11.018. Epub 2017 Feb 8. Mol Ther. 2017. PMID: 28187947 Free PMC article.
Only WT BMCs had a beneficial effect beyond 6 months, suggesting a dual mechanism of BMC benefit: a non-specific effect early after cell delivery, possibly due to the recruitment of macrophages and neutrophils, and a late beneficial effect dependent on long-term CFTR expre …
Only WT BMCs had a beneficial effect beyond 6 months, suggesting a dual mechanism of BMC benefit: a non-specific effect early after cell del …
The effect of multiple micronutrient supplementation on quality of life in patients with symptomatic heart failure secondary to ischemic heart disease: a prospective case series clinical study.
Wong AP, Mohamed AL, Niedzwiecki A. Wong AP, et al. Am J Cardiovasc Dis. 2015 Sep 15;5(3):146-52. eCollection 2015. Am J Cardiovasc Dis. 2015. PMID: 26417534 Free PMC article.
A high dose of multiple micronutrients may have beneficial effects on cardiac function in patients with symptomatic heart failure. This study indicates the need for long-term controlled studies to test the efficacy and safety of this economic approach in managing heart fai …
A high dose of multiple micronutrients may have beneficial effects on cardiac function in patients with symptomatic heart failure. This stud …
Comparison of open and minimally invasive surgery for intradural-extramedullary spine tumors.
Wong AP, Lall RR, Dahdaleh NS, Lawton CD, Smith ZA, Wong RH, Harvey MJ, Lam S, Koski TR, Fessler RG. Wong AP, et al. Neurosurg Focus. 2015 Aug;39(2):E11. doi: 10.3171/2015.5.FOCUS15129. Neurosurg Focus. 2015. PMID: 26235009
Studies of patients undergoing open resection of these tumors have reported high rates of gross-total resection (GTR) with minimal long-term neurological deficit. Case reports and small case series have suggested that these patients may be successfully treated with minimal …
Studies of patients undergoing open resection of these tumors have reported high rates of gross-total resection (GTR) with minimal long-t …
Evidence-based management of deep wound infection after spinal instrumentation.
Lall RR, Wong AP, Lall RR, Lawton CD, Smith ZA, Dahdaleh NS. Lall RR, et al. Among authors: wong ap. J Clin Neurosci. 2015 Feb;22(2):238-42. doi: 10.1016/j.jocn.2014.07.010. Epub 2014 Oct 11. J Clin Neurosci. 2015. PMID: 25308619 Review.
Surgeons should be aware that for deformity patients, even if solid fusion is observed, removal of instrumentation may be associated with significant loss of correction. A course of intravenous antibiotics followed by long-term oral suppressive therapy should be pursued if …
Surgeons should be aware that for deformity patients, even if solid fusion is observed, removal of instrumentation may be associated with si …
Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF): surgical technique, long-term 4-year prospective outcomes, and complications compared with an open TLIF cohort.
Wong AP, Smith ZA, Stadler JA 3rd, Hu XY, Yan JZ, Li XF, Lee JH, Khoo LT. Wong AP, et al. Neurosurg Clin N Am. 2014 Apr;25(2):279-304. doi: 10.1016/j.nec.2013.12.007. Epub 2014 Feb 18. Neurosurg Clin N Am. 2014. PMID: 24703447 Review.
The evidence base suggests that MI-TLIF can be performed safely with excellent long-term outcomes....
The evidence base suggests that MI-TLIF can be performed safely with excellent long-term outcomes....
Comparison of symptomatic cerebral spinal fluid leak between patients undergoing minimally invasive versus open lumbar foraminotomy, discectomy, or laminectomy.
Wong AP, Shih P, Smith TR, Slimack NP, Dahdaleh NS, Aoun SG, El Ahmadieh TY, Smith ZA, Scheer JK, Koski TR, Liu JC, Fessler RG. Wong AP, et al. World Neurosurg. 2014 Mar-Apr;81(3-4):634-40. doi: 10.1016/j.wneu.2013.11.012. Epub 2013 Nov 13. World Neurosurg. 2014. PMID: 24239738
OBJECTIVE: Minimally invasive spine surgery (MISS) techniques have similar long-term outcomes compared to open surgery for patients undergoing 1- or 2-level discectomy, foraminotomy, or laminectomy. ...
OBJECTIVE: Minimally invasive spine surgery (MISS) techniques have similar long-term outcomes compared to open surgery for patients u …
Minimally invasive thoracic decompression for multi-level thoracic pathologies.
Smith ZA, Lawton CD, Wong AP, Dahdaleh NS, Nixon AT, Ganju A, Fessler RG. Smith ZA, et al. Among authors: wong ap. J Clin Neurosci. 2014 Mar;21(3):467-72. doi: 10.1016/j.jocn.2013.07.010. Epub 2013 Aug 8. J Clin Neurosci. 2014. PMID: 24153324
Complete decompression was achieved with resolution of symptoms in all patients. Long-term follow-up averaged 26.7 months (range: 15-36 months). Radiographic decompression was demonstrated in all patients. Minimal access techniques using muscle-splitting tubular retractor …
Complete decompression was achieved with resolution of symptoms in all patients. Long-term follow-up averaged 26.7 months (range: 15- …
The effect of surgical level on self-reported clinical outcomes after minimally invasive transforaminal lumbar interbody fusion: L4-L5 versus L5-S1.
Lawton CD, Smith ZA, Nixon AT, Dahdaleh NS, Wong AP, Khanna R, Barnawi A, Fessler RG. Lawton CD, et al. Among authors: wong ap. World Neurosurg. 2014 Jan;81(1):177-82. doi: 10.1016/j.wneu.2013.07.082. Epub 2013 Aug 3. World Neurosurg. 2014. PMID: 23916495
There was no significant difference in mean operating time, intraoperative blood loss, and hospital stay (P = 0.937, 0.627, and 0.587). There was no significant difference in the long-term postoperative questionnaire results (P = 0.819 for VAS [back], 0.626 for VAS [leg], …
There was no significant difference in mean operating time, intraoperative blood loss, and hospital stay (P = 0.937, 0.627, and 0.587). Ther …
Targeted cell replacement with bone marrow cells for airway epithelial regeneration.
Wong AP, Dutly AE, Sacher A, Lee H, Hwang DM, Liu M, Keshavjee S, Hu J, Waddell TK. Wong AP, et al. Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L740-52. doi: 10.1152/ajplung.00050.2007. Epub 2007 Jul 6. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17616650 Free article.
Here, we show that the combination of mild airway injury (naphthalene-induced) as a conditioning regimen to direct the site of BMC localization and transtracheal delivery of short-term cultured BMC enhances airway localization and adoption of an epithelial-like phenotype. …
Here, we show that the combination of mild airway injury (naphthalene-induced) as a conditioning regimen to direct the site of BMC localizat …
12 results