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Alterations in relaxation to lactate and H(2)O(2) in human placental vessels from gestational diabetic pregnancies.
Figueroa R, Martinez E, Fayngersh RP, Tejani N, Mohazzab-H KM, Wolin MS. Figueroa R, et al. Among authors: wolin ms. Am J Physiol Heart Circ Physiol. 2000 Mar;278(3):H706-13. doi: 10.1152/ajpheart.2000.278.3.H706. Am J Physiol Heart Circ Physiol. 2000. PMID: 10710337 Free article.
Isolated placental arteries and veins from GDM and uncomplicated full-term pregnancies were precontracted with prostaglandin F(2alpha) (PO(2) 35-38 Torr) and then exposed to lactate (1-10 mM), arachidonic acid (0.01-10 microM), nitroglycerin (1 nM-1 microM), forskolin (0.0 …
Isolated placental arteries and veins from GDM and uncomplicated full-term pregnancies were precontracted with prostaglandin F(2alpha …
Nitric oxide and the depressor response to angiotensin blockade in hypertension.
Guan H, Cachofeiro V, Pucci ML, Kaminski PM, Wolin MS, Nasjletti A. Guan H, et al. Among authors: wolin ms. Hypertension. 1996 Jan;27(1):19-24. doi: 10.1161/01.hyp.27.1.19. Hypertension. 1996. PMID: 8591882
We investigated the contribution of nitric oxide to the short-term blood pressure reduction caused by interruption of the renin-angiotensin system in angiotensin-dependent hypertension. ...Pretreatment with NG-nitro-L-arginine methyl ester did not interfere with the vasode …
We investigated the contribution of nitric oxide to the short-term blood pressure reduction caused by interruption of the renin-angio …
Absence of relaxation to lactate in human placental vessels of pregnancies with severe preeclampsia.
Figueroa R, Martinez E, Fayngersh RP, Jiang H, Omar HA, Tejani N, Wolin MS. Figueroa R, et al. Among authors: wolin ms. Am J Obstet Gynecol. 1995 Dec;173(6):1800-6. doi: 10.1016/0002-9378(95)90430-1. Am J Obstet Gynecol. 1995. PMID: 8610765
STUDY DESIGN: Isolated placental arteries and veins from women with severe preeclampsia and uncomplicated term pregnancies were precontracted with prostaglandin F2 alpha under 5% oxygen and 5% carbon dioxide with the balance nitrogen (Po2 35 to 38 torr) and then exposed to …
STUDY DESIGN: Isolated placental arteries and veins from women with severe preeclampsia and uncomplicated term pregnancies were preco …
Properties of a lactate-induced relaxation in human placental arteries and veins.
Omar HA, Figueroa R, Tejani N, Wolin MS. Omar HA, et al. Among authors: wolin ms. Am J Obstet Gynecol. 1993 Oct;169(4):912-8. doi: 10.1016/0002-9378(93)90026-f. Am J Obstet Gynecol. 1993. PMID: 7901993
STUDY DESIGN: Isolated 1 to 2 mm human placental arteries and veins from normal term pregnancies, precontracted with prostaglandin F2 alpha and incubated under a PO2 of approximately 35 torr were exposed to lactate, 1 to 10 mmol/L, (pH 7.4), pyruvate, hydrogen peroxide, ni …
STUDY DESIGN: Isolated 1 to 2 mm human placental arteries and veins from normal term pregnancies, precontracted with prostaglandin F2 …
Gestational diabetes alters human placental vascular responses to changes in oxygen tension.
Figueroa R, Omar HA, Tejani N, Wolin MS. Figueroa R, et al. Among authors: wolin ms. Am J Obstet Gynecol. 1993 May;168(5):1616-22. doi: 10.1016/s0002-9378(11)90807-2. Am J Obstet Gynecol. 1993. PMID: 8498450
OBJECTIVE: Our objective was to study tone responses caused by hypoxia, reoxygenation, and hydrogen peroxide in human placental vessels from gestational diabetic and normal term pregnancies. STUDY DESIGN: Isolated placental arteries and veins from women with well-controlle …
OBJECTIVE: Our objective was to study tone responses caused by hypoxia, reoxygenation, and hydrogen peroxide in human placental vessels from …
Properties of an endogenous arachidonic acid--elicited relaxing mechanism in human placental vessels.
Omar HA, Figueroa R, Omar RA, Wolin MS. Omar HA, et al. Among authors: wolin ms. Am J Obstet Gynecol. 1992 Oct;167(4 Pt 1):1064-70. doi: 10.1016/s0002-9378(12)80039-1. Am J Obstet Gynecol. 1992. PMID: 1329513
STUDY DESIGN: Pharmacologic probes and endothelium-removal were used to examine the mechanism of relaxation to arachidonic acid (10 nmol/L to 10 mumol/L) observed in placental arteries and veins obtained after delivery from uncomplicated term pregnancies and precontracted …
STUDY DESIGN: Pharmacologic probes and endothelium-removal were used to examine the mechanism of relaxation to arachidonic acid (10 nmol/L t …
Hydrogen peroxide and reoxygenation cause prostaglandin-mediated contraction of human placental arteries and veins.
Omar HA, Figueroa R, Omar RA, Tejani N, Wolin MS. Omar HA, et al. Among authors: wolin ms. Am J Obstet Gynecol. 1992 Jul;167(1):201-7. doi: 10.1016/s0002-9378(11)91658-5. Am J Obstet Gynecol. 1992. PMID: 1442927
STUDY DESIGN: Endothelium-intact and denuded arteries and veins (1 to 2 mm diameter, from normal term deliveries), incubated under 95% oxygen/5% carbon dioxide or 5% oxygen/5% carbon dioxide (balance nitrogen) and precontracted with 1 to 10 nmol/L U46619, were exposed to h …
STUDY DESIGN: Endothelium-intact and denuded arteries and veins (1 to 2 mm diameter, from normal term deliveries), incubated under 95 …