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Co-administering Melatonin With an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mammary Cancer Development in a Mouse Model of HER2-Positive Breast Cancer.
Dodda BR, Bondi CD, Hasan M, Clafshenkel WP, Gallagher KM, Kotlarczyk MP, Sethi S, Buszko E, Latimer JJ, Cline JM, Witt-Enderby PA, Davis VL. Dodda BR, et al. Among authors: witt enderby pa. Front Oncol. 2019 Jul 9;9:525. doi: 10.3389/fonc.2019.00525. eCollection 2019. Front Oncol. 2019. PMID: 31355130 Free PMC article.
Melatonin supplementation influenced mammary morphology by increasing tertiary branching in the mouse mammary glands and differentiation in human mammary epithelial cell cultures. Uterine weight in the luteal phase was elevated after long-term exposure to EPT, but not to M …
Melatonin supplementation influenced mammary morphology by increasing tertiary branching in the mouse mammary glands and differentiation in …
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.
Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, Baranov SV, Leronni D, Mihalik AC, He Y, Cecon E, Wehbi VL, Kim J, Heath BE, Baranova OV, Wang X, Gable MJ, Kretz ES, Di Benedetto G, Lezon TR, Ferrando LM, Larkin TM, Sullivan M, Yablonska S, Wang J, Minnigh MB, Guillaumet G, Suzenet F, Richardson RM, Poloyac SM, Stolz DB, Jockers R, Witt-Enderby PA, Carlisle DL, Vilardaga JP, Friedlander RM. Suofu Y, et al. Among authors: witt enderby pa. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7997-E8006. doi: 10.1073/pnas.1705768114. Epub 2017 Sep 5. Proc Natl Acad Sci U S A. 2017. PMID: 28874589 Free PMC article.
These findings coupled with our observation that mitochondrial MT(1) overexpression reduces ischemic brain injury in mice delineate a mitochondrial GPCR mechanism contributing to the neuroprotective action of melatonin. We propose a new term, "automitocrine," analogous to …
These findings coupled with our observation that mitochondrial MT(1) overexpression reduces ischemic brain injury in mice delineate a mitoch …
Platelet-rich preparations to improve healing. Part I: workable options for every size practice.
Davis VL, Abukabda AB, Radio NM, Witt-Enderby PA, Clafshenkel WP, Cairone JV, Rutkowski JL. Davis VL, et al. Among authors: witt enderby pa. J Oral Implantol. 2014 Aug;40(4):500-10. doi: 10.1563/AAID-JOI-D-12-00104. J Oral Implantol. 2014. PMID: 25106016 Review.
Platelet-rich preparations accelerate healing at earlier time points to reduce discomfort and the potential for adverse outcomes, including infection, poor wound closure, and delays in forming strong bone for subsequent procedures (such as implants). However, platelet-rich prepar …
Platelet-rich preparations accelerate healing at earlier time points to reduce discomfort and the potential for adverse outcomes, including …