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Optimizing evidence-based practice implementation: a case study on simulated patient protocols in long-term opioid therapy.
Green E, Hamm M, Gowl C, Van Deusen R, Liebschutz JM, Wilson JD, Merlin J. Green E, et al. Among authors: wilson jd. Implement Sci Commun. 2024 Apr 22;5(1):44. doi: 10.1186/s43058-024-00575-y. Implement Sci Commun. 2024. PMID: 38649982 Free PMC article.
DESIGN: We observed 12 clinicians' first-time experiences with six unique decision-making algorithms, developed previously using rigorous Delphi methods, for use with patients exhibiting concerning behaviors associated with long-term opioid therapy (LTOT) for chronic pain. …
DESIGN: We observed 12 clinicians' first-time experiences with six unique decision-making algorithms, developed previously using rigorous De …
Timing of Radiotherapy (RT) After Radical Prostatectomy (RP): Long-term outcomes in the RADICALS-RT trial [NCT00541047].
Parker CC, Petersen PM, Cook AD, Clarke NW, Catton C, Cross WR, Kynaston H, Parulekar WR, Persad RA, Saad F, Bower L, Durkan GC, Logue J, Maniatis C, Noor D, Payne H, Anderson J, Bahl AK, Bashir F, Bottomley DM, Brasso K, Capaldi L, Cooke PW, Chung C, Donohue J, Eddy B, Heath CM, Henderson A, Henry A, Jaganathan R, Jakobsen H, James ND, Joseph J, Lees K, Lester J, Lindberg H, Makar A, Morris SL, Oommen N, Ostler P, Owen L, Patel P, Pope A, Popert R, Raman R, Ramani V, Røder A, Sayers I, Simms M, Srinivasan V, Sundaram S, Tarver KL, Tran A, Wells P, Wilson J, Zarkar AM, Parmar MKM, Sydes MR; RADICALS investigators. Parker CC, et al. Among authors: wilson j. Ann Oncol. 2024 Apr 5:S0923-7534(24)00105-4. doi: 10.1016/j.annonc.2024.03.010. Online ahead of print. Ann Oncol. 2024. PMID: 38583574
Adjuvant-RT reported worse urinary and faecal incontinence one year after randomisation (p=0.001); faecal incontinence remained significant after ten years (p=0.017). INTERPRETATION: Long-term results from RADICALS-RT confirm adjuvant RT after radical prostatectomy increas …
Adjuvant-RT reported worse urinary and faecal incontinence one year after randomisation (p=0.001); faecal incontinence remained significant …
STING-Pathway Inhibiting Nanoparticles (SPINs) as a Platform for Treatment of Inflammatory Diseases.
Pastora LE, Namburu NS, Arora K, Christov PP, Wilson JT. Pastora LE, et al. Among authors: wilson jt. ACS Appl Bio Mater. 2024 Apr 2. doi: 10.1021/acsabm.3c01305. Online ahead of print. ACS Appl Bio Mater. 2024. PMID: 38563162 Review.
However, these agents require frequent high-dose intraperitoneal injections, which may limit translatability. Furthermore, long-term use of systemically administered cGAS/STING inhibitors may leave patients vulnerable to viral infections and cancer. ...
However, these agents require frequent high-dose intraperitoneal injections, which may limit translatability. Furthermore, long-term …
Association between inflammation and post-intensive care syndrome: a systematic review.
Docherty C, Page C, Wilson J, Ross P, Garrity K, Quasim T, Shaw M, McPeake J. Docherty C, et al. Among authors: wilson j. Anaesthesia. 2024 Mar 20. doi: 10.1111/anae.16258. Online ahead of print. Anaesthesia. 2024. PMID: 38508699 Review.
Overall, there was mixed evidence of a potential association between an inflammatory process and long-term patient outcomes following critical illness. Further high-quality research is required to develop a longitudinal inflammatory profile of survivors of critical illness …
Overall, there was mixed evidence of a potential association between an inflammatory process and long-term patient outcomes following …
Designing an Implementable Clinical Prediction Model for Near-Term Mortality and Long-Term Survival in Patients on Maintenance Hemodialysis.
Goldstein BA, Xu C, Wilson J, Henao R, Ephraim PL, Weiner DE, Shafi T, Scialla JJ. Goldstein BA, et al. Among authors: wilson j. Am J Kidney Dis. 2024 Feb 21:S0272-6386(24)00594-8. doi: 10.1053/j.ajkd.2023.12.013. Online ahead of print. Am J Kidney Dis. 2024. PMID: 38493378
Knowledge of life-expectancy may focus care decisions on near-term versus long-term goals. The current tools are limited and focus on near-term mortality. ...Both near-term and long-term models have similar predictive performance, but the long- …
Knowledge of life-expectancy may focus care decisions on near-term versus long-term goals. The current tools are limited and f …
Effectiveness of septoplasty compared to medical management in adults with obstruction associated with a deviated nasal septum: the NAIROS RCT.
Carrie S, Fouweather T, Homer T, O'Hara J, Rousseau N, Rooshenas L, Bray A, Stocken DD, Ternent L, Rennie K, Clark E, Waugh N, Steel AJ, Dooley J, Drinnan M, Hamilton D, Lloyd K, Oluboyede Y, Wilson C, Gardiner Q, Kara N, Khwaja S, Leong SC, Maini S, Morrison J, Nix P, Wilson JA, Teare MD. Carrie S, et al. Among authors: wilson ja. Health Technol Assess. 2024 Mar;28(10):1-213. doi: 10.3310/MVFR4028. Health Technol Assess. 2024. PMID: 38477237 Free PMC article. Clinical Trial.
Most patients who we spoke to after a septoplasty were happy with their treatment, but some would have liked more information about what to expect after their nose surgery. In the short term, septoplasty is more costly than medical management. However, over the longer t …
Most patients who we spoke to after a septoplasty were happy with their treatment, but some would have liked more information about what to …
The Effects of Peri-Operative Adverse Events on Clinical and Patient-Reported Outcomes After Surgery for Degenerative Cervical Myelopathy: An Observational Cohort Study from the Canadian Spine Outcomes and Research Network.
Malhotra AK, Evaniew N, Dea N, Fisher CG, Street JT, Cadotte DW, Jacobs WB, Thomas KC, Attabib N, Manson N, Hall H, Bailey CS, Nataraj A, Phan P, Rampersaud YR, Paquet J, Weber MH, Christie SD, McIntosh G, Wilson JR. Malhotra AK, et al. Among authors: wilson jr. Neurosurgery. 2024 Mar 11. doi: 10.1227/neu.0000000000002896. Online ahead of print. Neurosurgery. 2024. PMID: 38465953
BACKGROUND AND OBJECTIVES: There is a lack of data examining the effects of perioperative adverse events (AEs) on long-term outcomes for patients undergoing surgery for degenerative cervical myelopathy. ...
BACKGROUND AND OBJECTIVES: There is a lack of data examining the effects of perioperative adverse events (AEs) on long-term outcomes …
Psychosocial impacts of being nil-by-mouth as an adult: A scoping review.
Hepper EC, Wilson J, Drinnan M, Patterson JM. Hepper EC, et al. Among authors: wilson j. J Adv Nurs. 2024 Feb 27. doi: 10.1111/jan.16100. Online ahead of print. J Adv Nurs. 2024. PMID: 38414146 Review.
Being nil by mouth (NBM) for short periods such as pre-operative fasting causes distress; however, little is understood about impact on longer-term abstinence from eating and drinking. WHAT THIS PAPER ADDS?: Psychosocial consequences of being nil by mouth (NBM)have been in …
Being nil by mouth (NBM) for short periods such as pre-operative fasting causes distress; however, little is understood about impact on long …
Serial Evaluation of Preimmunization Antibody Titers in Lymphoma Patients Receiving Chimeric Antigen Receptor T Cell Therapy.
Bansal R, Vergidis P, Tosh PK, Wilson J, Hathcock M, Khurana A, Bennani NN, Paludo J, Villasboas JC, Wang Y, Ansell SM, Johnston PB, Freeman C, Lin Y. Bansal R, et al. Among authors: wilson j. Transplant Cell Ther. 2024 Apr;30(4):455.e1-455.e7. doi: 10.1016/j.jtct.2024.02.003. Epub 2024 Feb 10. Transplant Cell Ther. 2024. PMID: 38346643 Free article.
Loss of antibody titers post-CAR-T is possible, highlighting the need for revaccination. Additional studies with long-term follow-up are needed to inform the optimal timing of immunization post-CAR-T....
Loss of antibody titers post-CAR-T is possible, highlighting the need for revaccination. Additional studies with long-term follow-up …
Blunt Head Injury in the Elderly: Analysis of the NEXUS II Injury Cohort.
Mower WR, Akie TE, Morizadeh N, Gupta M, Hendey GW, Wilson JL, Leonid Duvergne LP, Ma P, Krishna P, Rodriguez RM. Mower WR, et al. Among authors: wilson jl. Ann Emerg Med. 2024 May;83(5):457-466. doi: 10.1016/j.annemergmed.2024.01.003. Epub 2024 Feb 10. Ann Emerg Med. 2024. PMID: 38340132 Free article.
Outcomes, particularly after intervention, can be poor, with high rates of long-term disability and mortality....
Outcomes, particularly after intervention, can be poor, with high rates of long-term disability and mortality....
703 results