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Evolution of nutritional management in children with cystic fibrosis - a narrative review.
Smith C, Lowdon J, Noordhoek J, Wilschanski M. Smith C, et al. Among authors: wilschanski m. J Hum Nutr Diet. 2024 Apr 25. doi: 10.1111/jhn.13298. Online ahead of print. J Hum Nutr Diet. 2024. PMID: 38664916 Review.
Specialised nutrition support will continue to be required, and it will be additionally important to improve and optimise quality of life and long-term health....
Specialised nutrition support will continue to be required, and it will be additionally important to improve and optimise quality of life an …
Infantile-onset inflammatory bowel disease has variable long-term outcomes.
Krauthammer A, Weintraub I, Shaoul R, Lev-Tzion R, Broide E, Wilschanski M, Lerner A, Yerushalmi B, Shouval DS, Shamaly H, Haberman-Ziv Y, Weiss B. Krauthammer A, et al. Among authors: wilschanski m. Front Pediatr. 2023 Mar 1;11:1097779. doi: 10.3389/fped.2023.1097779. eCollection 2023. Front Pediatr. 2023. PMID: 36937967 Free PMC article.
OBJECTIVE AND AIM: Infantile-onset inflammatory bowel disease (IO-IBD), defined as IBD diagnosed at age 2 years or younger, tends to be more severe and refractory to conventional treatment than IBD diagnosed at a later age. However, data about IO-IBD and its long-term foll …
OBJECTIVE AND AIM: Infantile-onset inflammatory bowel disease (IO-IBD), defined as IBD diagnosed at age 2 years or younger, tends to be more …
Nutritional and metabolic management for cystic fibrosis in a post-cystic fibrosis transmembrane conductance modulator era.
Wilschanski M, Peckham D. Wilschanski M, et al. Curr Opin Pulm Med. 2022 Nov 1;28(6):577-583. doi: 10.1097/MCP.0000000000000917. Epub 2022 Sep 14. Curr Opin Pulm Med. 2022. PMID: 36102602 Review.
SUMMARY: Nutritional and metabolic management of pwCF needs to change in order to maximize long term health and avoid future complications relating to obesity and increased cardiovascular risk. Longitudinal registry studies will be key to improve our understanding of the l …
SUMMARY: Nutritional and metabolic management of pwCF needs to change in order to maximize long term health and avoid future complica …
The effect of probiotic administration on metabolomics and glucose metabolism in CF patients.
Gur M, Zuckerman-Levin N, Masarweh K, Hanna M, Laghi L, Marazzato M, Levanon S, Hakim F, Bar-Yoseph R, Wilschanski M, Bentur L. Gur M, et al. Among authors: wilschanski m. Pediatr Pulmonol. 2022 Oct;57(10):2335-2343. doi: 10.1002/ppul.26037. Epub 2022 Jun 15. Pediatr Pulmonol. 2022. PMID: 35676769 Free PMC article.
CONCLUSIONS: Changes in urine and stool metabolic profiles, following the administration of probiotics, may suggest a positive effect on glucose metabolism in CF. Larger long-term studies are needed to confirm our findings. Understanding the interplay between dysbiosis, in …
CONCLUSIONS: Changes in urine and stool metabolic profiles, following the administration of probiotics, may suggest a positive effect on glu …
Management of Gastrointestinal and Nutritional Problems in Children With Neurological Impairment: A Survey of Practice.
Romano C, Dipasquale V, Van Winckel M, Hulst J, Broekaert I, Bronsky J, Dall'Oglio L, Mis NF, Hojsak I, Orel R, Papadopoulou A, Schaeppi M, Thapar N, Wilschanski M, Sullivan P, Gottrand F. Romano C, et al. Among authors: wilschanski m. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):e97-e101. doi: 10.1097/MPG.0000000000003020. J Pediatr Gastroenterol Nutr. 2021. PMID: 33346573
Regarding tube feeding, nearly all respondents (n = 114) agreed that gastrostomy is the best enteral access to be used for long-term enteral feeding. Fundoplication was indicated at the time of gastrostomy placement especially in case of uncontrolled GERD. ...
Regarding tube feeding, nearly all respondents (n = 114) agreed that gastrostomy is the best enteral access to be used for long-term …
The Use of Jejunal Tube Feeding in Children: A Position Paper by the Gastroenterology and Nutrition Committees of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition 2019.
Broekaert IJ, Falconer J, Bronsky J, Gottrand F, Dall'Oglio L, Goto E, Hojsak I, Hulst J, Kochavi B, Papadopoulou A, Ribes-Koninckx C, Schaeppi M, Werlin S, Wilschanski M, Thapar N. Broekaert IJ, et al. Among authors: wilschanski m. J Pediatr Gastroenterol Nutr. 2019 Aug;69(2):239-258. doi: 10.1097/MPG.0000000000002379. J Pediatr Gastroenterol Nutr. 2019. PMID: 31169666
Seventeen clinical questions treating indications and contraindications, investigations before placement, techniques of placement, suitable feeds and feeding regimen, weaning from JTF, complications, long-term care, and ethical considerations were addressed.A systematic li …
Seventeen clinical questions treating indications and contraindications, investigations before placement, techniques of placement, suitable …
Cystic Fibrosis-related Liver Disease: Research Challenges and Future Perspectives.
Debray D, Narkewicz MR, Bodewes FAJA, Colombo C, Housset C, de Jonge HR, Jonker JW, Kelly DA, Ling SC, Poynard T, Sogni P, Trauner M, Witters P, Baumann U, Wilschanski M, Verkade HJ. Debray D, et al. Among authors: wilschanski m. J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):443-448. doi: 10.1097/MPG.0000000000001676. J Pediatr Gastroenterol Nutr. 2017. PMID: 28753176
A deeper understanding of the pathophysiology and prognostic factors for the long-term evolution of CFLD is fundamental to move forward and has a strong bearing on identifying potential treatments. ...
A deeper understanding of the pathophysiology and prognostic factors for the long-term evolution of CFLD is fundamental to move forwa …
Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group.
Gariepy CE, Heyman MB, Lowe ME, Pohl JF, Werlin SL, Wilschanski M, Barth B, Fishman DS, Freedman SD, Giefer MJ, Gonska T, Himes R, Husain SZ, Morinville VD, Ooi CY, Schwarzenberg SJ, Troendle DM, Yen E, Uc A. Gariepy CE, et al. Among authors: wilschanski m. J Pediatr Gastroenterol Nutr. 2017 Jan;64(1):95-103. doi: 10.1097/MPG.0000000000001446. J Pediatr Gastroenterol Nutr. 2017. PMID: 27782962 Free PMC article.
RESULTS: The panel reached consensus on 27 statements covering the definitions of pediatric ARP and CP, evaluation for potential etiologies of these disorders, and long-term monitoring. Statements for which the group reached consensus to make no recommendation or could not …
RESULTS: The panel reached consensus on 27 statements covering the definitions of pediatric ARP and CP, evaluation for potential etiologies …
Cancer risk among lung transplant recipients with cystic fibrosis.
Fink AK, Yanik EL, Marshall BC, Wilschanski M, Lynch CF, Austin AA, Copeland G, Safaeian M, Engels EA. Fink AK, et al. Among authors: wilschanski m. J Cyst Fibros. 2017 Jan;16(1):91-97. doi: 10.1016/j.jcf.2016.07.011. Epub 2016 Aug 15. J Cyst Fibros. 2017. PMID: 27539828 Free PMC article.
Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice.
Rosen C, Shezen E, Aronovich A, Klionsky YZ, Yaakov Y, Assayag M, Biton IE, Tal O, Shakhar G, Ben-Hur H, Shneider D, Vaknin Z, Sadan O, Evron S, Freud E, Shoseyov D, Wilschanski M, Berkman N, Fibbe WE, Hagin D, Hillel-Karniel C, Krentsis IM, Bachar-Lustig E, Reisner Y. Rosen C, et al. Among authors: wilschanski m. Nat Med. 2015 Aug;21(8):869-79. doi: 10.1038/nm.3889. Epub 2015 Jul 13. Nat Med. 2015. PMID: 26168294
Intravenous infusion of a single cell suspension of canalicular lung tissue from GFP-marked mice or human fetal donors into naphthalene-injured and irradiated syngeneic or SCID mice, respectively, induced marked long-term lung chimerism. Donor type structures or 'patches' …
Intravenous infusion of a single cell suspension of canalicular lung tissue from GFP-marked mice or human fetal donors into naphthalene-inju …
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