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High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations.
Hinshaw RG, Schroeder MK, Ciola J, Varma C, Colletti B, Liu B, Liu GG, Shi Q, Williams JP, O'Banion MK, Caldarone BJ, Lemere CA. Hinshaw RG, et al. Among authors: williams jp. Int J Mol Sci. 2023 Feb 10;24(4):3615. doi: 10.3390/ijms24043615. Int J Mol Sci. 2023. PMID: 36835027 Free PMC article.
In general, the Alzheimer's model mice were more prone than their wildtype littermates to radiation-induced behavior changes, and hippocampal staining for amyloid beta pathology and microglial activation in these mice revealed a dose-dependent reduction in males but not in female …
In general, the Alzheimer's model mice were more prone than their wildtype littermates to radiation-induced behavior changes, and hippocampa …
Combined high-voltage pulsed radiofrequency and ozone therapy versus ozone therapy alone in treating postherpetic neuralgia: a retrospective comparison.
Zhang JF, Williams JP, Zhao QN, Liu H, An JX. Zhang JF, et al. Among authors: williams jp. Med Gas Res. 2023 Jan-Mar;13(1):15-22. doi: 10.4103/2045-9912.352660. Med Gas Res. 2023. PMID: 35946218 Free PMC article.
Moreover, treatment effects and total efficacy rates tended to be higher for the combination of PRF and ozone than ozone alone. This conclusion was especially true for long-term therapeutic effects....
Moreover, treatment effects and total efficacy rates tended to be higher for the combination of PRF and ozone than ozone alone. This conclus …
Long-Term Sex- and Genotype-Specific Effects of (56)Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice.
Schroeder MK, Liu B, Hinshaw RG, Park MA, Wang S, Dubey S, Liu GG, Shi Q, Holton P, Reiser V, Jones PA, Trigg W, Di Carli MF, Caldarone BJ, Williams JP, O'Banion MK, Lemere CA. Schroeder MK, et al. Among authors: williams jp. Int J Mol Sci. 2021 Dec 10;22(24):13305. doi: 10.3390/ijms222413305. Int J Mol Sci. 2021. PMID: 34948098 Free PMC article.
There is evidence that (56)Fe irradiation, a significant component of space radiation, may be more harmful to males than to females and worsen Alzheimer's disease pathology in genetically vulnerable models. Yet, research on the long-term, sex- and genotype-specific effects …
There is evidence that (56)Fe irradiation, a significant component of space radiation, may be more harmful to males than to females and wors …
Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery.
Doleman B, Leonardi-Bee J, Heinink TP, Boyd-Carson H, Carrick L, Mandalia R, Lund JN, Williams JP. Doleman B, et al. Among authors: williams jp. Cochrane Database Syst Rev. 2021 Jun 14;6(6):CD012978. doi: 10.1002/14651858.CD012978.pub2. Cochrane Database Syst Rev. 2021. PMID: 34125958 Free PMC article.
There may be little or no difference between the groups in short-term (RR 1.00, 95% CI 0.34 to 2.94; studies = 2; participants = 100; I(2) = 0%; low-certainty evidence) or long-term nausea and vomiting (RR 0.85, 95% CI 0.52 to 1.38; studies = 5; participants = 228; …
There may be little or no difference between the groups in short-term (RR 1.00, 95% CI 0.34 to 2.94; studies = 2; participants = 100; …
Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management.
Abboud H, Probasco J, Irani SR, Ances B, Benavides DR, Bradshaw M, Christo PP, Dale RC, Fernandez-Fournier M, Flanagan EP, Gadoth A, George P, Grebenciucova E, Jammoul A, Lee ST, Li Y, Matiello M, Morse AM, Rae-Grant A, Rojas G, Rossman I, Schmitt S, Venkatesan A, Vernino S, Pittock SJ, Titulaer M; Autoimmune Encephalitis Alliance Clinicians Network. Abboud H, et al. J Neurol Neurosurg Psychiatry. 2021 Mar 1;92(8):897-907. doi: 10.1136/jnnp-2020-325302. Online ahead of print. J Neurol Neurosurg Psychiatry. 2021. PMID: 33649021 Free PMC article. Review.
Radiation-Induced Damage to Prepubertal Pax7+ Skeletal Muscle Stem Cells Drives Lifelong Deficits in Myofiber Size and Nuclear Number.
Bachman JF, Blanc RS, Paris ND, Kallenbach JG, Johnston CJ, Hernady E, Williams JP, Chakkalakal JV. Bachman JF, et al. Among authors: williams jp. iScience. 2020 Nov 2;23(11):101760. doi: 10.1016/j.isci.2020.101760. eCollection 2020 Nov 20. iScience. 2020. PMID: 33241204 Free PMC article.
Indeed, some muscle regenerative capacity persisted immediately after irradiation. Lastly, we assessed the long-term consequences of radiation-induced SC loss during prepuberty. ...
Indeed, some muscle regenerative capacity persisted immediately after irradiation. Lastly, we assessed the long-term consequences of …
Feasibility of Patient-Controlled Sleep with Dexmedetomidine in Treating Chronic Intractable Insomnia.
An JX, Williams JP, Fang QW, Wang Y, Liu H, Shi L, Zhang WH. An JX, et al. Among authors: williams jp. Nat Sci Sleep. 2020 Nov 19;12:1033-1042. doi: 10.2147/NSS.S262991. eCollection 2020. Nat Sci Sleep. 2020. PMID: 33239930 Free PMC article.
However, it is an off-label use, and the potential side effects of dexmedetomidine with long-term use needs further evaluation....
However, it is an off-label use, and the potential side effects of dexmedetomidine with long-term use needs further evaluation....
High-intensity interval training produces a significant improvement in fitness in less than 31 days before surgery for urological cancer: a randomised control trial.
Blackwell JEM, Doleman B, Boereboom CL, Morton A, Williams S, Atherton P, Smith K, Williams JP, Phillips BE, Lund JN. Blackwell JEM, et al. Among authors: williams jp. Prostate Cancer Prostatic Dis. 2020 Dec;23(4):696-704. doi: 10.1038/s41391-020-0219-1. Epub 2020 Mar 10. Prostate Cancer Prostatic Dis. 2020. PMID: 32157250 Free PMC article. Clinical Trial.
Larger randomised trials are required to investigate the efficacy of prehabilitation HIIT upon different cancer types, post-operative complications, socio-economic impact and long-term survival....
Larger randomised trials are required to investigate the efficacy of prehabilitation HIIT upon different cancer types, post-operative compli …
Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice.
Hinkle JJ, Olschowka JA, Love TM, Williams JP, O'Banion MK. Hinkle JJ, et al. Among authors: williams jp. Sci Rep. 2019 Dec 11;9(1):18899. doi: 10.1038/s41598-019-55366-6. Sci Rep. 2019. PMID: 31827187 Free PMC article.
Cranial irradiation is the main therapeutic treatment for primary and metastatic malignancies in the brain. However, cranial radiation therapy produces long-term impairment in memory, information processing, and attention that contribute to a decline in quality of life. .. …
Cranial irradiation is the main therapeutic treatment for primary and metastatic malignancies in the brain. However, cranial radiation thera …
Space-like 56Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer's-like transgenic mice.
Liu B, Hinshaw RG, Le KX, Park MA, Wang S, Belanger AP, Dubey S, Frost JL, Shi Q, Holton P, Trojanczyk L, Reiser V, Jones PA, Trigg W, Di Carli MF, Lorello P, Caldarone BJ, Williams JP, O'Banion MK, Lemere CA. Liu B, et al. Among authors: williams jp. Sci Rep. 2019 Aug 20;9(1):12118. doi: 10.1038/s41598-019-48615-1. Sci Rep. 2019. PMID: 31431669 Free PMC article.
Space travel will expose people to high-energy, heavy particle radiation, and the cognitive deficits induced by this exposure are not well understood. To investigate the short-term effects of space radiation, we irradiated 4-month-old Alzheimer's disease (AD)-like transgen …
Space travel will expose people to high-energy, heavy particle radiation, and the cognitive deficits induced by this exposure are not well u …
45 results