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Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome and Potential Therapeutics.
Leng A, Shah M, Ahmad SA, Premraj L, Wildi K, Li Bassi G, Pardo CA, Choi A, Cho SM. Leng A, et al. Among authors: wildi k. Cells. 2023 Mar 6;12(5):816. doi: 10.3390/cells12050816. Cells. 2023. PMID: 36899952 Free PMC article. Review.
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more than four weeks after primary infection, termed "long COVID" or post-acute sequela of COVID-19 (PASC), can implicate persistent neurological complications in up to one third of patients and p …
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more than four weeks after primary infection, termed "lo …
Design and Rationale of a Prospective International Follow-Up Study on Intensive Care Survivors of COVID-19: The Long-Term Impact in Intensive Care Survivors of Coronavirus Disease-19-AFTERCOR.
Wildi K, Li Bassi G, Barnett A, Panigada M, Colombo SM, Bandera A, Muscatello A, McNicholas B, Laffey JG, Battaglini D, Robba C, Torres A, Motos A, Luna CM, Rainieri F, Hodgson C, Burrell AJC, Buscher H, Dalton H, Cho SM, Choi HA, Thomson D, Suen J, Fraser JF. Wildi K, et al. Front Med (Lausanne). 2021 Sep 8;8:738086. doi: 10.3389/fmed.2021.738086. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34568393 Free PMC article.
Background: In a disease that has only existed for 18 months, it is difficult to be fully informed of the long-term sequelae of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. ...Methods: This is an international multi-center, prospective long-te …
Background: In a disease that has only existed for 18 months, it is difficult to be fully informed of the long-term sequelae of sever …
Predicting Major Adverse Events in Patients With Acute Myocardial Infarction.
Nestelberger T, Boeddinghaus J, Wussler D, Twerenbold R, Badertscher P, Wildi K, Miró Ò, López B, Martin-Sanchez FJ, Muzyk P, Koechlin L, Baumgartner B, Meier M, Troester V, Rubini Giménez M, Puelacher C, du Fay de Lavallaz J, Walter J, Kozhuharov N, Zimmermann T, Gualandro DM, Michou E, Potlukova E, Geigy N, Keller DI, Reichlin T, Mueller C; APACE Investigators. Nestelberger T, et al. Among authors: wildi k. J Am Coll Cardiol. 2019 Aug 20;74(7):842-854. doi: 10.1016/j.jacc.2019.06.025. J Am Coll Cardiol. 2019. PMID: 31416527 Free article.
BACKGROUND: Early and accurate detection of short-term major adverse cardiac events (MACE) in patients with suspected acute myocardial infarction (AMI) is an unmet clinical need. ...
BACKGROUND: Early and accurate detection of short-term major adverse cardiac events (MACE) in patients with suspected acute myocardia …
External Validation of the MEESSI Acute Heart Failure Risk Score: A Cohort Study.
Wussler D, Kozhuharov N, Sabti Z, Walter J, Strebel I, Scholl L, Miró O, Rossello X, Martín-Sánchez FJ, Pocock SJ, Nowak A, Badertscher P, Twerenbold R, Wildi K, Puelacher C, du Fay de Lavallaz J, Shrestha S, Strauch O, Flores D, Nestelberger T, Boeddinghaus J, Schumacher C, Goudev A, Pfister O, Breidthardt T, Mueller C. Wussler D, et al. Among authors: wildi k. Ann Intern Med. 2019 Feb 19;170(4):248-256. doi: 10.7326/M18-1967. Epub 2019 Jan 29. Ann Intern Med. 2019. PMID: 30690646
Performance in patients with terminal kidney failure who are receiving long-term dialysis cannot be commented on. CONCLUSION: External validation of the MEESSI-AHF risk score showed excellent discrimination. ...
Performance in patients with terminal kidney failure who are receiving long-term dialysis cannot be commented on. CONCLUSION: Externa …
Perioperative Myocardial Injury After Noncardiac Surgery: Incidence, Mortality, and Characterization.
Puelacher C, Lurati Buse G, Seeberger D, Sazgary L, Marbot S, Lampart A, Espinola J, Kindler C, Hammerer A, Seeberger E, Strebel I, Wildi K, Twerenbold R, du Fay de Lavallaz J, Steiner L, Gurke L, Breidthardt T, Rentsch K, Buser A, Gualandro DM, Osswald S, Mueller C; BASEL-PMI Investigators. Puelacher C, et al. Among authors: wildi k. Circulation. 2018 Mar 20;137(12):1221-1232. doi: 10.1161/CIRCULATIONAHA.117.030114. Epub 2017 Dec 4. Circulation. 2018. PMID: 29203498
CONCLUSIONS: PMI is a common complication after noncardiac surgery and, despite early detection during routine clinical screening, is associated with substantial short- and long-term mortality. Mortality seems comparable in patients with PMI not fulfilling any other of the …
CONCLUSIONS: PMI is a common complication after noncardiac surgery and, despite early detection during routine clinical screening, is associ …
Complement activation products in acute heart failure: Potential role in pathophysiology, responses to treatment and impacts on long-term survival.
Trendelenburg M, Stallone F, Pershyna K, Eisenhut T, Twerenbold R, Wildi K, Dubler D, Schirmbeck L, Puelacher C, Rubini Gimenez M, Sabti Z, Osswald L, Breidthardt T, Müller C. Trendelenburg M, et al. Among authors: wildi k. Eur Heart J Acute Cardiovasc Care. 2018 Jun;7(4):348-357. doi: 10.1177/2048872617694674. Epub 2017 Feb 1. Eur Heart J Acute Cardiovasc Care. 2018. PMID: 29064269
The aim of our study was to explore the potential role of innate immunity - quantified by complement activation products (CAPs) - in pathophysiology, responses to treatment and impacts on long-term survival in AHF. METHODS: In a prospective study enrolling 179 unselected p …
The aim of our study was to explore the potential role of innate immunity - quantified by complement activation products (CAPs) - in pathoph …
Direct Comparison of Cardiac Myosin-Binding Protein C With Cardiac Troponins for the Early Diagnosis of Acute Myocardial Infarction.
Kaier TE, Twerenbold R, Puelacher C, Marjot J, Imambaccus N, Boeddinghaus J, Nestelberger T, Badertscher P, Sabti Z, Giménez MR, Wildi K, Hillinger P, Grimm K, Loeffel S, Shrestha S, Widmer DF, Cupa J, Kozhuharov N, Miró Ò, Martín-Sánchez FJ, Morawiec B, Rentsch K, Lohrmann J, Kloos W, Osswald S, Reichlin T, Weber E, Marber M, Mueller C. Kaier TE, et al. Among authors: wildi k. Circulation. 2017 Oct 17;136(16):1495-1508. doi: 10.1161/CIRCULATIONAHA.117.028084. Epub 2017 Sep 26. Circulation. 2017. PMID: 28972002 Free PMC article.
The final diagnosis of AMI was independently adjudicated using all available clinical and biochemical information without knowledge of cMyC. The prognostic end point was long-term mortality. RESULTS: Final diagnosis was AMI in 340 patients (17%). ...
The final diagnosis of AMI was independently adjudicated using all available clinical and biochemical information without knowledge of cMyC. …
Impact of haemoconcentration during acute heart failure therapy on mortality and its relationship with worsening renal function.
Breidthardt T, Weidmann ZM, Twerenbold R, Gantenbein C, Stallone F, Rentsch K, Rubini Gimenez M, Kozhuharov N, Sabti Z, Breitenbücher D, Wildi K, Puelacher C, Honegger U, Wagener M, Schumacher C, Hillinger P, Osswald S, Mueller C. Breidthardt T, et al. Among authors: wildi k. Eur J Heart Fail. 2017 Feb;19(2):226-236. doi: 10.1002/ejhf.667. Epub 2016 Oct 19. Eur J Heart Fail. 2017. PMID: 27758007 Free article.
We aimed to characterize further the impact of in-hospital haemoconcentration and worsening renal function (WRF) on short- and long-term mortality. METHODS AND RESULTS: Haematocrit, haemoglobin, total protein, serum creatinine, and albumin levels were measured serially in …
We aimed to characterize further the impact of in-hospital haemoconcentration and worsening renal function (WRF) on short- and long-term …
Characterization of the observe zone of the ESC 2015 high-sensitivity cardiac troponin 0h/1h-algorithm for the early diagnosis of acute myocardial infarction.
Nestelberger T, Wildi K, Boeddinghaus J, Twerenbold R, Reichlin T, Giménez MR, Puelacher C, Jaeger C, Grimm K, Sabti Z, Hillinger P, Kozhuharov N, du Fay de Lavallaz J, Pinck F, Lopez B, Salgado E, Miró Ò, Bingisser R, Lohrmann J, Osswald S, Mueller C. Nestelberger T, et al. Among authors: wildi k. Int J Cardiol. 2016 Mar 15;207:238-45. doi: 10.1016/j.ijcard.2016.01.112. Epub 2016 Jan 11. Int J Cardiol. 2016. PMID: 26808985
CONCLUSION: "Observe" patients are typically elderly men with pre-existing CAD and high long-term mortality. Absolute hs-cTn-changes within 3h, functional stress imaging and coronary angiography are the key diagnostic modalities....
CONCLUSION: "Observe" patients are typically elderly men with pre-existing CAD and high long-term mortality. Absolute hs-cTn-changes …
Misdiagnosis of Myocardial Infarction Related to Limitations of the Current Regulatory Approach to Define Clinical Decision Values for Cardiac Troponin.
Wildi K, Gimenez MR, Twerenbold R, Reichlin T, Jaeger C, Heinzelmann A, Arnold C, Nelles B, Druey S, Haaf P, Hillinger P, Schaerli N, Kreutzinger P, Tanglay Y, Herrmann T, Moreno Weidmann Z, Krivoshei L, Freese M, Stelzig C, Puelacher C, Rentsch K, Osswald S, Mueller C. Wildi K, et al. Circulation. 2015 Jun 9;131(23):2032-40. doi: 10.1161/CIRCULATIONAHA.114.014129. Epub 2015 May 6. Circulation. 2015. PMID: 25948541 Free PMC article.
The incidence of inconsistencies was only 7.0% for assays with CDVs that were nearly biologically equivalent. Patients with inconsistent AMI had long-term mortality comparable to that of patients with consistent diagnoses (P=NS) and a trend toward higher long-term m …
The incidence of inconsistencies was only 7.0% for assays with CDVs that were nearly biologically equivalent. Patients with inconsistent AMI …
18 results