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Physical and Cognitive Impairment in Acute Respiratory Failure.
Taylor J, Wilcox ME. Taylor J, et al. Among authors: wilcox me. Crit Care Clin. 2024 Apr;40(2):429-450. doi: 10.1016/j.ccc.2024.01.009. Epub 2024 Feb 7. Crit Care Clin. 2024. PMID: 38432704 Review.
The complex interrelationship between physical disability, cognitive dysfunction, and long-term patient-centered outcomes is explored. This review highlights the need for comprehensive, multidisciplinary approaches to mitigate morbidity and accelerate recovery....
The complex interrelationship between physical disability, cognitive dysfunction, and long-term patient-centered outcomes is explored …
Advancing specificity in delirium: The delirium subtyping initiative.
Bowman EML, Brummel NE, Caplan GA, Cunningham C, Evered LA, Fiest KM, Girard TD, Jackson TA, LaHue SC, Lindroth HL, Maclullich AMJ, McAuley DF, Oh ES, Oldham MA, Page VJ, Pandharipande PP, Potter KM, Sinha P, Slooter AJC, Sweeney AM, Tieges Z, Van Dellen E, Wilcox ME, Zetterberg H, Cunningham EL. Bowman EML, et al. Among authors: wilcox me. Alzheimers Dement. 2024 Jan;20(1):183-194. doi: 10.1002/alz.13419. Epub 2023 Jul 31. Alzheimers Dement. 2024. PMID: 37522255 Free PMC article.
BACKGROUND: Delirium, a common syndrome with heterogeneous etiologies and clinical presentations, is associated with poor long-term outcomes. Recording and analyzing all delirium equally could be hindering the field's understanding of pathophysiology and identification of …
BACKGROUND: Delirium, a common syndrome with heterogeneous etiologies and clinical presentations, is associated with poor long-term o …
Study protocol for a randomized controlled trial of Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: the PROMIZING study.
Bosma KJ, Martin CM, Burns KEA, Mancebo Cortes J, Suárez Montero JC, Skrobik Y, Thorpe KE, Amaral ACK, Arabi Y, Basmaji J, Beduneau G, Beloncle F, Carteaux G, Charbonney E, Demoule A, Dres M, Fanelli V, Geagea A, Goligher E, Lellouche F, Maraffi T, Mercat A, Rodriguez PO, Shahin J, Sibley S, Spadaro S, Vaporidi K, Wilcox ME, Brochard L; Canadian Critical Care Trials Group and; REVA Network. Bosma KJ, et al. Among authors: wilcox me. Trials. 2023 Mar 27;24(1):232. doi: 10.1186/s13063-023-07163-w. Trials. 2023. PMID: 36973743 Free PMC article.
The proportional assistance, called the gain, can be adjusted by the clinician to maintain the patient's respiratory effort or workload within a normal range. Short-term and physiological benefits of this mode compared to pressure support ventilation (PSV) include better p …
The proportional assistance, called the gain, can be adjusted by the clinician to maintain the patient's respiratory effort or workload with …
Association of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness.
Fernando SM, Scott M, Talarico R, Fan E, McIsaac DI, Sood MM, Myran DT, Herridge MS, Needham DM, Hodgson CL, Rochwerg B, Munshi L, Wilcox ME, Bienvenu OJ, MacLaren G, Fowler RA, Scales DC, Ferguson ND, Combes A, Slutsky AS, Brodie D, Tanuseputro P, Kyeremanteng K. Fernando SM, et al. Among authors: wilcox me. JAMA. 2022 Nov 8;328(18):1827-1836. doi: 10.1001/jama.2022.17714. JAMA. 2022. PMID: 36286084 Free PMC article.
IMPORTANCE: Extracorporeal membrane oxygenation (ECMO) is used as temporary cardiorespiratory support in critically ill patients, but little is known regarding long-term psychiatric sequelae among survivors after ECMO. OBJECTIVE: To investigate the association between ECMO …
IMPORTANCE: Extracorporeal membrane oxygenation (ECMO) is used as temporary cardiorespiratory support in critically ill patients, but little …
The central nervous system during lung injury and mechanical ventilation: a narrative review.
Albaiceta GM, Brochard L, Dos Santos CC, Fernández R, Georgopoulos D, Girard T, Jubran A, López-Aguilar J, Mancebo J, Pelosi P, Skrobik Y, Thille AW, Wilcox ME, Blanch L. Albaiceta GM, et al. Among authors: wilcox me. Br J Anaesth. 2021 Oct;127(4):648-659. doi: 10.1016/j.bja.2021.05.038. Epub 2021 Jul 31. Br J Anaesth. 2021. PMID: 34340836 Free article. Review.
Further, it proposes directions for future research ranging from identifying mechanisms of multiorgan failure to mitigating long-term sequelae after critical illness....
Further, it proposes directions for future research ranging from identifying mechanisms of multiorgan failure to mitigating long-term …
Delirium and long term cognition in critically ill patients.
Wilcox ME, Girard TD, Hough CL. Wilcox ME, et al. BMJ. 2021 Jun 8;373:n1007. doi: 10.1136/bmj.n1007. BMJ. 2021. PMID: 34103334 Review.
Clinical trials have provided a limited understanding of the contributions of multiple triggers and processes of intensive care unit (ICU) acquired delirium, making identification of therapies difficult. Delirium is independently associated with poor long term outcomes, in …
Clinical trials have provided a limited understanding of the contributions of multiple triggers and processes of intensive care unit (ICU) a …
Sleep Fragmentation and Cognitive Trajectories After Critical Illness.
Wilcox ME, McAndrews MP, Van J, Jackson JC, Pinto R, Black SE, Lim AS, Friedrich JO, Rubenfeld GD. Wilcox ME, et al. Chest. 2021 Jan;159(1):366-381. doi: 10.1016/j.chest.2020.07.036. Epub 2020 Jul 24. Chest. 2021. PMID: 32717265
RESEARCH QUESTION: Is there an association between sleep, long-term cognition, and APOE status in ICU survivors? STUDY DESIGN AND METHODS: We enrolled 150 patients from five centers who had been mechanically ventilated for at least 3 days; 102 patients survived to ICU disc …
RESEARCH QUESTION: Is there an association between sleep, long-term cognition, and APOE status in ICU survivors? STUDY DESIGN AND MET …
20 results