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Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis.
Mukherjee D, Previs RA, Haines C, Al Abo M, Juras PK, Strickland KC, Chakraborty B, Artham S, Whitaker RS, Hebert K, Fontenot J, Patierno SR, Freedman JA, Lau FH, Burow ME, Chang CY, McDonnell DP. Mukherjee D, et al. Among authors: whitaker rs. Cancer Res. 2023 Sep 1;83(17):2889-2907. doi: 10.1158/0008-5472.CAN-22-1622. Cancer Res. 2023. PMID: 37335130 Free PMC article.
Despite some treatment successes in early-stage localized TNBC, the rate of distant recurrence remains high, and long-term survival outcomes remain poor. In a search for new therapeutic targets for this disease, we observed that elevated expression of the serine/threonine …
Despite some treatment successes in early-stage localized TNBC, the rate of distant recurrence remains high, and long-term survival o …
Health Care Use and Spending Among Need-Based Subgroups of Medicare Beneficiaries With Full Medicaid Benefits.
Kaufman BG, Jones KA, Greiner MA, Giri A, Stewart L, He A, Clark AG, Taylor DH Jr, Bundorf MK, Whitaker RG, Van Houtven CH, Higgins A. Kaufman BG, et al. Among authors: whitaker rg. JAMA Health Forum. 2023 May 5;4(5):e230973. doi: 10.1001/jamahealthforum.2023.0973. JAMA Health Forum. 2023. PMID: 37171797 Free PMC article.
The diversity of health care use suggests a tailored approach to integration strategies with comprehensive set benefits that comprises Medicare and Medicaid services, including long-term services and supports, BH, palliative care, and social services....
The diversity of health care use suggests a tailored approach to integration strategies with comprehensive set benefits that comprises Medic …
Ca 2+ /Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis.
Mukherjee D, Previs RA, Haines CN, Abo MA, Juras PK, Strickland KC, Chakraborty B, Artham S, Whitaker R, Hebert KL, Fontenot J, Patierno SR, Freedman JA, Lau FH, Burow M, Chang CY, McDonnell DP. Mukherjee D, et al. Among authors: whitaker r. bioRxiv [Preprint]. 2023 Apr 18:2023.04.17.536051. doi: 10.1101/2023.04.17.536051. bioRxiv. 2023. PMID: 37131673 Free PMC article. Preprint.
Despite some successes in the initial treatment of patients diagnosed with early-stage localized TNBC, the rate of metastatic recurrence remains high with poor long-term survival outcomes. Here we show that elevated expression of the serine/threonine-kinase, Calcium/Calmod …
Despite some successes in the initial treatment of patients diagnosed with early-stage localized TNBC, the rate of metastatic recurrence rem …
Machine Learning in Metopic Craniosynostosis: Does Phenotypic Severity Predict Long-Term Esthetic Outcome?
Blum JD, Beiriger J, Villavisanis DF, Morales C, Cho DY, Tao W, Whitaker R, Bartlett SP, Taylor JA, Goldstein JA, Swanson JW. Blum JD, et al. Among authors: whitaker r. J Craniofac Surg. 2023 Jan-Feb 01;34(1):58-64. doi: 10.1097/SCS.0000000000008868. Epub 2022 Aug 10. J Craniofac Surg. 2023. PMID: 35946829 Free PMC article.
BACKGROUND: There have been few longitudinal studies assessing the effect of preoperative phenotypic severity on long-term esthetic outcomes in metopic craniosynostosis. This study evaluates the relationship between metopic severity and long-term esthetic outcomes u …
BACKGROUND: There have been few longitudinal studies assessing the effect of preoperative phenotypic severity on long-term esthetic o …
Intraspecific antagonism through viral toxin encoded by chronic Sulfolobus spindle-shaped virus.
DeWerff SJ, Zhang C, Schneider J, Whitaker RJ. DeWerff SJ, et al. Among authors: whitaker rj. Philos Trans R Soc Lond B Biol Sci. 2022 Jan 17;377(1842):20200476. doi: 10.1098/rstb.2020.0476. Epub 2021 Nov 29. Philos Trans R Soc Lond B Biol Sci. 2022. PMID: 34839697 Free PMC article.
Virus-host interactions evolve along a symbiosis continuum from antagonism to mutualism. Long-term associations between virus and host, such as those in chronic infection, will select for traits that drive the interaction towards mutualism, especially when susceptible host …
Virus-host interactions evolve along a symbiosis continuum from antagonism to mutualism. Long-term associations between virus and hos …
Leveraging unsupervised image registration for discovery of landmark shape descriptor.
Bhalodia R, Elhabian S, Kavan L, Whitaker R. Bhalodia R, et al. Among authors: whitaker r. Med Image Anal. 2021 Oct;73:102157. doi: 10.1016/j.media.2021.102157. Epub 2021 Jul 9. Med Image Anal. 2021. PMID: 34293535 Free PMC article.
We use landmark-driven image registration as the primary task to force the neural network to discover landmarks that register the images well. We also propose a regularization term that allows for robust optimization of the neural network and ensures that the landmarks uni …
We use landmark-driven image registration as the primary task to force the neural network to discover landmarks that register the images wel …
Epigenetic Regulation of Claudin-1 in the Development of Ovarian Cancer Recurrence and Drug Resistance.
Visco ZR, Sfakianos G, Grenier C, Boudreau MH, Simpson S, Rodriguez I, Whitaker R, Yao DY, Berchuck A, Murphy SK, Huang Z. Visco ZR, et al. Among authors: whitaker r. Front Oncol. 2021 Mar 22;11:620873. doi: 10.3389/fonc.2021.620873. eCollection 2021. Front Oncol. 2021. PMID: 33828978 Free PMC article.
An independent dataset showed that this correlation is stronger in tumors from short-term (<3y) survivors than in tumors from long-term (>7y) survivors (R= -0.41 to -0.46 versus R= 0.06 to -0.19, respectively). The presence of this inverse correlation in short …
An independent dataset showed that this correlation is stronger in tumors from short-term (<3y) survivors than in tumors from long …
Community-Based Measurements Reveal Unseen Differences during Air Pollution Episodes.
Kelly KE, Xing WW, Sayahi T, Mitchell L, Becnel T, Gaillardon PE, Meyer M, Whitaker RT. Kelly KE, et al. Among authors: whitaker rt. Environ Sci Technol. 2021 Jan 5;55(1):120-128. doi: 10.1021/acs.est.0c02341. Epub 2020 Dec 16. Environ Sci Technol. 2021. PMID: 33325230
Short-term exposure to fine particulate matter (PM(2.5)) pollution is linked to numerous adverse health effects. ...
Short-term exposure to fine particulate matter (PM(2.5)) pollution is linked to numerous adverse health effects. ...
45 results