Rapid Correction of the Hypoglycemia State in Nonhuman Primates Using a Glucagon Long-Dissolving Microneedle Patch.
Yu X, Wen X, Xu J, Zhou Q, Chen Y, Qu F, He M, Chang H, Zheng C.
Yu X, et al. Among authors: wen x.
ACS Biomater Sci Eng. 2024 Apr 8. doi: 10.1021/acsbiomaterials.3c01962. Online ahead of print.
ACS Biomater Sci Eng. 2024.
PMID: 38588325
The GLMN patch was observed to reverse the effects of hypoglycemia within 15 min of application in animal models (specifically, rat and rhesus monkey models) and maintained long-term glycemic control, owing to highly efficient drug permeation and the drug reservoir effect …
The GLMN patch was observed to reverse the effects of hypoglycemia within 15 min of application in animal models (specifically, rat and rhes …