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Four-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma.
Sangro B, Chan SL, Kelley RK, Lau G, Kudo M, Sukeepaisarnjaroen W, Yarchoan M, De Toni EN, Furuse J, Kang YK, Galle PR, Rimassa L, Heurgué A, Tam VC, Van Dao T, Thungappa SC, Breder V, Ostapenko Y, Reig M, Makowsky M, Paskow MJ, Gupta C, Kurland JF, Negro A, Abou-Alfa GK; HIMALAYA investigators. Sangro B, et al. Ann Oncol. 2024 Feb 19:S0923-7534(24)00049-8. doi: 10.1016/j.annonc.2024.02.005. Online ahead of print. Ann Oncol. 2024. PMID: 38382875 Free article.
Long-term survivors with STRIDE (n = 103) included participants across clinically relevant subgroups, and 57.3% (59/103) had no reported subsequent anticancer therapy. ...Results continue to support the long-term benefits of STRIDE in a diverse population, reflectiv …
Long-term survivors with STRIDE (n = 103) included participants across clinically relevant subgroups, and 57.3% (59/103) had no repor …
Combination of Osimertinib and Olaparib Therapy to Treat Non-Small Cell Lung Cancer and High-Grade Serous Ovarian Carcinoma: A Case Report.
Lin J, Welch S, Sanatani M, Ramadan S. Lin J, et al. Among authors: welch s. Curr Oncol. 2024 Jan 19;31(1):558-565. doi: 10.3390/curroncol31010039. Curr Oncol. 2024. PMID: 38275832 Free PMC article.
These two drugs can either be given in an alternating way or given together, short-term, with a higher but tolerable toxicity profile....
These two drugs can either be given in an alternating way or given together, short-term, with a higher but tolerable toxicity profile …
Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.
Gupta S, Subhedar NV, Bell JL, Field D, Bowler U, Hutchison E, Johnson S, Kelsall W, Pepperell J, Roberts T, Sinha S, Stanbury K, Wyllie J, Hardy P, Juszczak E; Baby-OSCAR Collaborative Group. Gupta S, et al. N Engl J Med. 2024 Jan 25;390(4):314-325. doi: 10.1056/NEJMoa2305582. N Engl J Med. 2024. PMID: 38265644 Free PMC article. Clinical Trial.
Whether selective early treatment of large PDAs with ibuprofen would improve short-term outcomes is not known. METHODS: We conducted a multicenter, randomized, double-blind, placebo-controlled trial evaluating early treatment (72 hours after birth) with ibuprofen fo …
Whether selective early treatment of large PDAs with ibuprofen would improve short-term outcomes is not known. METHODS: We conducted …
Epiretinal membrane in uveitis: Rate, visual prognosis, complications and surgical outcomes.
Yap A, Lu LM, Sims JL, Welch S, Niederer RL. Yap A, et al. Among authors: welch s. Clin Exp Ophthalmol. 2024 Jan-Feb;52(1):54-62. doi: 10.1111/ceo.14338. Epub 2023 Dec 18. Clin Exp Ophthalmol. 2024. PMID: 38108156
BACKGROUND: Epiretinal membrane (ERM) is a common finding in patients with uveitis that contributes to visual impairment. We describe the long-term visual acuity (VA) and morphometric progression in patients with uveitis and epiretinal membrane (ERM). ...CONCLUSIONS: In ad …
BACKGROUND: Epiretinal membrane (ERM) is a common finding in patients with uveitis that contributes to visual impairment. We describe the lo …
ECGI targeted ablation for persistent AF not responding to pulmonary vein isolation: Results of a two-staged strategy (TARGET AF2).
Dhillon G, Honarbakhsh S, Abbas H, Waddingham P, Dennis AS, Ahluwalia N, Finlay M, Sohaib A, Welch S, Daw H, Sporton S, Chow A, Earley MJ, Lambiase PD, Hunter RJ. Dhillon G, et al. Among authors: welch s. Heart Rhythm O2. 2023 Aug 31;4(10):609-617. doi: 10.1016/j.hroo.2023.08.004. eCollection 2023 Oct. Heart Rhythm O2. 2023. PMID: 37936670 Free PMC article.
CONCLUSIONS: In patients with recurrent AF despite PVI, ECGI-guided ablation caused an acute response in a majority with reasonable long-term outcomes....
CONCLUSIONS: In patients with recurrent AF despite PVI, ECGI-guided ablation caused an acute response in a majority with reasonable long- …
Adjuvant carboplatin and paclitaxel with "sandwich" method radiotherapy for stage III or IV endometrial cancer: long-term follow-up at a single-institution.
Chinnadurai A, Breadner D, Baloush Z, Lohmann AE, Black M, D'Souza D, Welch S. Chinnadurai A, et al. Among authors: welch s. J Gynecol Oncol. 2024 Mar;35(2):e16. doi: 10.3802/jgo.2024.35.e16. Epub 2023 Oct 16. J Gynecol Oncol. 2024. PMID: 37921600 Free PMC article.
Histological subtype, location of positive nodes, and cancer stage (IIIa vs. higher stage) did not correlate to a higher risk of recurrence or death. CONCLUSION: Long term follow-up and a larger population confirm that the chemoradiotherapy sandwich method yields favorable …
Histological subtype, location of positive nodes, and cancer stage (IIIa vs. higher stage) did not correlate to a higher risk of recurrence …
Role of Antimicrobial Resistance in Outcomes of Acute Endophthalmitis.
Yap A, Muttaiyah S, Welch S, Niederer RL. Yap A, et al. Among authors: welch s. Antibiotics (Basel). 2023 Jul 28;12(8):1246. doi: 10.3390/antibiotics12081246. Antibiotics (Basel). 2023. PMID: 37627666 Free PMC article.
BACKGROUND: This study explores local trends in antimicrobial resistance and its influence on long-term visual outcomes following treatment with broad-spectrum empiric intravitreal antibiotics. ...
BACKGROUND: This study explores local trends in antimicrobial resistance and its influence on long-term visual outcomes following tre …
Effect of physical and occupational therapy on delirium duration in older emergency department patients who are hospitalized.
Jordano JO, Vasilevskis EE, Duggan MC, Welch SA, Schnelle JF, Simmons SF, Ely EW, Han JH. Jordano JO, et al. Among authors: welch sa. J Am Coll Emerg Physicians Open. 2023 Feb 6;4(1):e12857. doi: 10.1002/emp2.12857. eCollection 2023 Feb. J Am Coll Emerg Physicians Open. 2023. PMID: 36776211 Free PMC article.
OBJECTIVE: Delirium in older emergency department (ED) adults is associated with poorer long-term physical function and cognition. We sought to evaluate if the time to and intensity of physical and/or occupational therapy (PT/OT) are associated with the duration of ED deli …
OBJECTIVE: Delirium in older emergency department (ED) adults is associated with poorer long-term physical function and cognition. We …
ECG-I phenotyping of persistent AF based on driver burden and distribution to predict response to pulmonary vein isolation (PHENOTYPE-AF).
Dhillon GS, Honarbakhsh S, Graham A, Abbass H, Welch S, Daw H, Sporton S, Providencia R, Chow A, Earley MJ, Lowe M, Lambiase PD, Schilling RJ, Hunter RJ. Dhillon GS, et al. Among authors: welch s. J Cardiovasc Electrophysiol. 2022 Nov;33(11):2263-2273. doi: 10.1111/jce.15644. Epub 2022 Aug 16. J Cardiovasc Electrophysiol. 2022. PMID: 35924481
BACKGROUND: This prospective trial sought to phenotype persistent atrial fibrillation (AF) based on AF mechanisms using electrocardiographic imaging (ECGI) mapping to determine whether this would predict long-term freedom from arrhythmia after pulmonary vein isolation (PVI …
BACKGROUND: This prospective trial sought to phenotype persistent atrial fibrillation (AF) based on AF mechanisms using electrocardiographic …
Clinical yarning with Aboriginal and/or Torres Strait Islander peoples-a systematic scoping review of its use and impacts.
Burke AW, Welch S, Power T, Lucas C, Moles RJ. Burke AW, et al. Among authors: welch s. Syst Rev. 2022 Jun 23;11(1):129. doi: 10.1186/s13643-022-02008-0. Syst Rev. 2022. PMID: 35739597 Free PMC article. Review.
STUDY DESIGN: Systematic scoping review of published literature. DATA SOURCES: A one-word search term "yarning" was applied in Scopus, EMBASE, CINAHL, MEDLINE, International Pharmaceutical Abstracts, Australian Public Affairs Information Service-Health, and the Aboriginal …
STUDY DESIGN: Systematic scoping review of published literature. DATA SOURCES: A one-word search term "yarning" was applied in Scopus …
60 results