SLIT3 deficiency attenuates pressure overload-induced cardiac fibrosis and remodeling.
Gong L, Wang S, Shen L, Liu C, Shenouda M, Li B, Liu X, Shaw JA, Wineman AL, Yang Y, Xiong D, Eichmann A, Evans SM, Weiss SJ, Si MS.
Gong L, et al. Among authors: weiss sj.
JCI Insight. 2020 Jun 18;5(12):e136852. doi: 10.1172/jci.insight.136852.
JCI Insight. 2020.
PMID: 32644051
Free PMC article.
In pulmonary hypertension and certain forms of congenital heart disease, ventricular pressure overload manifests at birth and is an obligate hemodynamic abnormality that stimulates myocardial fibrosis, which leads to ventricular dysfunction and poor clinical outcomes. ...W …
In pulmonary hypertension and certain forms of congenital heart disease, ventricular pressure overload manifests at birth and is an o …