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Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland.
Schöbi N, Sanchez C, Welzel T, Bamford A, Webb K, Rojo P, Tremoulet A, Atkinson A, Schlapbach LJ, Bielicki JA; Swissped-RECOVERY trial group. Schöbi N, et al. Among authors: webb k. BMJ Open. 2024 Apr 25;14(4):e078137. doi: 10.1136/bmjopen-2023-078137. BMJ Open. 2024. PMID: 38670610 Free article. Clinical Trial.
Elevated risk for psychiatric outcomes in pediatric patients with Multisystem Inflammatory Syndrome (MIS-C): A review of neuroinflammatory and psychosocial stressors.
Pan T, Gallo ME, Donald KA, Webb K, Bath KG. Pan T, et al. Among authors: webb k. Brain Behav Immun Health. 2024 Mar 18;38:100760. doi: 10.1016/j.bbih.2024.100760. eCollection 2024 Jul. Brain Behav Immun Health. 2024. PMID: 38586284 Free PMC article. Review.
Although many of these symptoms resolve following anti-inflammatory treatment, the long-term neurological and psychiatric sequelae of MIS-C are unknown. ...
Although many of these symptoms resolve following anti-inflammatory treatment, the long-term neurological and psychiatric sequelae of …
Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial.
Ahmed I, Hudson J, Innes K, Hernández R, Gillies K, Bruce R, Bell V, Avenell A, Blazeby J, Brazzelli M, Cotton S, Croal B, Forrest M, MacLennan G, Murchie P, Wileman S, Ramsay C; C-GALL Study Group. Ahmed I, et al. BMJ. 2023 Dec 6;383:e075383. doi: 10.1136/bmj-2023-075383. BMJ. 2023. PMID: 38084426 Free PMC article. Clinical Trial.
Conservative management was less costly (mean difference -1033, (-$1334; -1205), 95% credible interval -1413 to -632) and QALYs did not differ (mean difference -0.019, 95% credible interval -0.06 to 0.02). CONCLUSIONS: In the short term (18 months), laparoscopic surgery is …
Conservative management was less costly (mean difference -1033, (-$1334; -1205), 95% credible interval -1413 to -632) and QALYs did not diff …
Healthier Together: Implementation and evaluation of a co-designed, culturally tailored childhood obesity community prevention program for Māori and Pacific Islander children and families.
Hardt J, Canfell OJ, Walker JL, Webb KL, Brignano S, Kira K, Peu T, Santos D, Bernard A, Littlewood R. Hardt J, et al. Among authors: webb kl. Health Promot J Austr. 2023 Oct 1. doi: 10.1002/hpja.803. Online ahead of print. Health Promot J Austr. 2023. PMID: 37779219
CONCLUSIONS: This study provides preliminary evidence that the Healthier Together program improved self-reported health behaviours and physical activity levels among Maori and Pacific Islander children and their families in the short-term; however, due to the small sample …
CONCLUSIONS: This study provides preliminary evidence that the Healthier Together program improved self-reported health behaviours and physi …
Expanded statistical analysis plan for legacy and long-term effects of aspirin in the ASPREE-XT observational follow-up study of participants in the ASPREE randomized trial.
Wolfe R, Broder J, Chan A, Murray A, Orchard S, Polekhina G, Ryan J, Tonkin A, Webb K, Woods R. Wolfe R, et al. Among authors: webb k. medRxiv [Preprint]. 2023 Sep 14:2023.09.13.23295514. doi: 10.1101/2023.09.13.23295514. medRxiv. 2023. PMID: 37745426 Free PMC article. Preprint.
We present a statistical analysis plan to underpin three main papers to report aspirin effects through to the fourth post-trial ASPREE-XT study visit with focus areas of: (1) death, dementia, and disability, (2) CVD events and bleeding, and (3) cancer. The focus of the plan is to …
We present a statistical analysis plan to underpin three main papers to report aspirin effects through to the fourth post-trial ASPREE-XT st …
PEG hydrogel containing dexamethasone-conjugated hyaluronic acid reduces secondary injury and improves motor function in a rat moderate TBI model.
Jones C, Elliott B, Liao Z, Johnson Z, Ma F, Bailey ZS, Gilsdorf J, Scultetus A, Shear D, Webb K, Lee JS. Jones C, et al. Among authors: webb k. Exp Neurol. 2023 Nov;369:114533. doi: 10.1016/j.expneurol.2023.114533. Epub 2023 Sep 4. Exp Neurol. 2023. PMID: 37666386
Traumatic brain injury (TBI) leads to long-term impairments in motor and cognitive function. TBI initiates a secondary injury cascade including a neuro-inflammatory response that is detrimental to tissue repair and limits recovery. ...
Traumatic brain injury (TBI) leads to long-term impairments in motor and cognitive function. TBI initiates a secondary injury cascade …
GFR Variability, Survival, and Cardiovascular Events in Older Adults.
Fravel MA, Ernst ME, Webb KL, Wetmore JB, Wolfe R, Woods RL, Reid CM, Chowdhury E, Murray AM, Polkinghorne KR; ASPirin in Reducing Events in the Elderly Investigator Group. Fravel MA, et al. Among authors: webb kl. Kidney Med. 2022 Dec 12;5(2):100583. doi: 10.1016/j.xkme.2022.100583. eCollection 2023 Feb. Kidney Med. 2022. PMID: 36794000 Free PMC article.
General practitioner perspectives on a shared-care model for paediatric patients post-intensive care: A cross-sectional survey.
Anthony L, Hilder A, Newcomb D, Webb KL, Best J, Stocker C, Long D. Anthony L, et al. Among authors: webb kl. Aust Crit Care. 2023 Jul;36(4):492-498. doi: 10.1016/j.aucc.2022.07.007. Epub 2022 Oct 6. Aust Crit Care. 2023. PMID: 36210281
METHODS: An anonymous, cross-sectional survey of 60 GPs, reached via private invitation (19% response) or via social media weblink, was conducted where the GPs were asked about their current confidence and knowledge in managing children post PICU. This included awareness of short …
METHODS: An anonymous, cross-sectional survey of 60 GPs, reached via private invitation (19% response) or via social media weblink, was cond …
Physiological predictors of morbidity and mortality in COPD: the relative importance of reduced inspiratory capacity and inspiratory muscle strength.
Phillips DB, James MD, O'Donnell CD, Vincent SG, Webb KA, de-Torres JP, Neder JA, O'Donnell DE. Phillips DB, et al. Among authors: webb ka. J Appl Physiol (1985). 2022 Sep 1;133(3):679-688. doi: 10.1152/japplphysiol.00352.2022. Epub 2022 Aug 11. J Appl Physiol (1985). 2022. PMID: 35952349 Free article.
The objective of the current study was to examine the interaction between resting IC and MIP (both % predicted), exertional dyspnea, exercise capacity, and long-term survival in patients with COPD. Two hundred and eighty-five patients with mild to advanced COPD completed s …
The objective of the current study was to examine the interaction between resting IC and MIP (both % predicted), exertional dyspnea, exercis …
Effectiveness-implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol.
Long D, Gibbons K, Dow B, Best J, Webb KL, Liley HG, Stocker C, Thoms D, Schlapbach LJ, Wharton C, Lister P, Matuschka L, Castillo MI, Tyack Z, Bora S. Long D, et al. Among authors: webb kl. BMJ Open. 2022 Jul 15;12(7):e060714. doi: 10.1136/bmjopen-2021-060714. BMJ Open. 2022. PMID: 35840297 Free PMC article.
INTRODUCTION: In Australia, while paediatric intensive care unit (PICU) mortality has dropped to 2.2%, one in three survivors experience long-term neurodevelopmental impairment, limiting their life-course opportunities. ...
INTRODUCTION: In Australia, while paediatric intensive care unit (PICU) mortality has dropped to 2.2%, one in three survivors experience lon …
71 results