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Divergent trajectories of antiviral memory after SARS-CoV-2 infection.
Tomic A, Skelly DT, Ogbe A, O'Connor D, Pace M, Adland E, Alexander F, Ali M, Allott K, Azim Ansari M, Belij-Rammerstorfer S, Bibi S, Blackwell L, Brown A, Brown H, Cavell B, Clutterbuck EA, de Silva T, Eyre D, Lumley S, Flaxman A, Grist J, Hackstein CP, Halkerston R, Harding AC, Hill J, James T, Jay C, Johnson SA, Kronsteiner B, Lie Y, Linder A, Longet S, Marinou S, Matthews PC, Mellors J, Petropoulos C, Rongkard P, Sedik C, Silva-Reyes L, Smith H, Stockdale L, Taylor S, Thomas S, Tipoe T, Turtle L, Vieira VA, Wrin T; OPTIC Clinical Group; PITCH Study Group; C-MORE Group; Pollard AJ, Lambe T, Conlon CP, Jeffery K, Travis S, Goulder P, Frater J, Mentzer AJ, Stafford L, Carroll MW, James WS, Klenerman P, Barnes E, Dold C, Dunachie SJ. Tomic A, et al. Nat Commun. 2022 Mar 10;13(1):1251. doi: 10.1038/s41467-022-28898-1. Nat Commun. 2022. PMID: 35273178 Free PMC article.
We identify a subgroup of participants with higher antibody responses and interferon-gamma ELISpot T cell responses, and a robust trajectory for longer term immunity associates with higher levels of neutralising antibodies against the infecting (Victoria) strain and also a …
We identify a subgroup of participants with higher antibody responses and interferon-gamma ELISpot T cell responses, and a robust trajectory …
Splinters in the fingernails, heart and brain: thromboembolic complications of non-bacterial thrombotic endocarditis despite treatment with a direct-acting oral anticoagulant.
Wang LW, Phan J, Schuetz P, Omari A, Watson AJ, Subbiah RN. Wang LW, et al. Among authors: watson aj. Oxf Med Case Reports. 2022 Jan 24;2022(1):omab138. doi: 10.1093/omcr/omab138. eCollection 2022 Jan. Oxf Med Case Reports. 2022. PMID: 35083053 Free PMC article.
Although systemic thromboembolism is a commonly associated condition, antiphospholipid syndrome is less common. Nevertheless, treatment generally involves long-term anticoagulation. We report a case of a patient with previously undiagnosed NBTE who suffered systemic thromb …
Although systemic thromboembolism is a commonly associated condition, antiphospholipid syndrome is less common. Nevertheless, treatment gene …
A systematic review of the effects of psychiatric medications on social cognition.
Haime Z, Watson AJ, Crellin N, Marston L, Joyce E, Moncrieff J. Haime Z, et al. Among authors: watson aj. BMC Psychiatry. 2021 Nov 29;21(1):597. doi: 10.1186/s12888-021-03545-z. BMC Psychiatry. 2021. PMID: 34844572 Free PMC article.
However, many of these studies were in patients already taking medication, and potential practice effects were identified due to short-term follow-ups. CONCLUSION: Healthy volunteer studies suggest that diazepam reduces emotional processing ability. ...
However, many of these studies were in patients already taking medication, and potential practice effects were identified due to short-te …
Videoconference clinics improve efficiency of inflammatory bowel disease care in a remote and rural setting.
Ruf B, Jenkinson P, Armour D, Fraser M, Watson AJ. Ruf B, et al. Among authors: watson aj. J Telemed Telecare. 2020 Oct;26(9):545-551. doi: 10.1177/1357633X19849280. Epub 2019 Jun 5. J Telemed Telecare. 2020. PMID: 31167590
INTRODUCTION: Patients with inflammatory bowel disease (IBD) require long-term secondary care with periodic specialist follow-up. This can be especially challenging for patients living in remote areas. ...
INTRODUCTION: Patients with inflammatory bowel disease (IBD) require long-term secondary care with periodic specialist follow-up. Thi …
Long-Term Planetary Habitability and the Carbonate-Silicate Cycle.
Rushby AJ, Johnson M, Mills BJW, Watson AJ, Claire MW. Rushby AJ, et al. Among authors: watson aj. Astrobiology. 2018 May;18(5):469-480. doi: 10.1089/ast.2017.1693. Astrobiology. 2018. PMID: 29791235 Free article.
Carbon dioxide is the most important greenhouse gas in Earth's atmosphere in terms of regulating planetary temperature, with the long-term concentration controlled by the balance between volcanic outgassing and the sequestration of CO(2) via chemical weathering and sedimen …
Carbon dioxide is the most important greenhouse gas in Earth's atmosphere in terms of regulating planetary temperature, with the long-ter …
Cost-Effectiveness of Haemorrhoidal Artery Ligation versus Rubber Band Ligation for the Treatment of Grade II-III Haemorrhoids: Analysis Using Evidence from the HubBLe Trial.
Alshreef A, Wailoo AJ, Brown SR, Tiernan JP, Watson AJM, Biggs K, Bradburn M, Hind D. Alshreef A, et al. Among authors: watson ajm. Pharmacoecon Open. 2017 Sep;1(3):175-184. doi: 10.1007/s41669-017-0023-6. Pharmacoecon Open. 2017. PMID: 29441497 Free PMC article.
METHOD: This analyses used data from the HubBLe study, a multicentre, open-label, parallel group, randomised controlled trial conducted in 17 acute UK hospitals between September 2012 and August 2015. A full economic evaluation, including long-term cost effectiveness, was …
METHOD: This analyses used data from the HubBLe study, a multicentre, open-label, parallel group, randomised controlled trial conducted in 1 …
A pragmatic multicentre randomised controlled trial comparing stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease: the eTHoS study.
Watson AJ, Cook J, Hudson J, Kilonzo M, Wood J, Bruhn H, Brown S, Buckley B, Curran F, Jayne D, Loudon M, Rajagopal R, McDonald A, Norrie J. Watson AJ, et al. Health Technol Assess. 2017 Nov;21(70):1-224. doi: 10.3310/hta21700. Health Technol Assess. 2017. PMID: 29205150 Free PMC article. Clinical Trial.
There were 774 participants included in the analysis as a result of one post-randomisation exclusion in the SH arm and two in the TH arm. SH was less painful than TH in the short term. Surgical complications were similar in both arms. EQ-5D-3L score was higher for the SH a …
There were 774 participants included in the analysis as a result of one post-randomisation exclusion in the SH arm and two in the TH arm. SH …
Comparison of stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease (eTHoS): a pragmatic, multicentre, randomised controlled trial.
Watson AJ, Hudson J, Wood J, Kilonzo M, Brown SR, McDonald A, Norrie J, Bruhn H, Cook JA; eTHoS study group. Watson AJ, et al. Lancet. 2016 Nov 12;388(10058):2375-2385. doi: 10.1016/S0140-6736(16)31803-7. Epub 2016 Oct 7. Lancet. 2016. PMID: 27726951 Free PMC article. Clinical Trial.
Stapled haemorrhoidopexy was less painful than traditional excisional surgery in the short term and surgical complication rates were similar between groups. ...
Stapled haemorrhoidopexy was less painful than traditional excisional surgery in the short term and surgical complication rates were …
35 results