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Exuberant fibroblast activity compromises lung function via ADAMTS4.
Nature. 2020 Nov;587(7834):466-471. doi: 10.1038/s41586-020-2877-5. Epub 2020 Oct 28.
Nature. 2020.
PMID: 33116313
Free PMC article.
Here we demonstrate that respiratory viral infection induces distinct fibroblast activation states, which we term extracellular matrix (ECM)-synthesizing, damage-responsive and interferon-responsive states. ...
Here we demonstrate that respiratory viral infection induces distinct fibroblast activation states, which we term extracellular matri …
Staphylococcus aureus toxin suppresses antigen-specific T cell responses.
Lee B, Olaniyi R, Kwiecinski JM, Wardenburg JB.
Lee B, et al. Among authors: wardenburg jb.
J Clin Invest. 2020 Mar 2;130(3):1122-1127. doi: 10.1172/JCI130728.
J Clin Invest. 2020.
PMID: 31873074
Free PMC article.
Within the human population, exposure to alpha-toxin through skin infection may modulate the establishment of T cell-mediated immunity, adversely affecting long-term protection. These studies prompt consideration that vaccination targeting S. aureus may be most effective i …
Within the human population, exposure to alpha-toxin through skin infection may modulate the establishment of T cell-mediated immunity, adve …
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