Galectin-1-mediated MET/AXL signaling enhances sorafenib resistance in hepatocellular carcinoma by escaping ferroptosis.
Hsu TW, Su YH, Chen HA, Liao PH, Shen SC, Tsai KY, Wang TH, Chen A, Huang CY, Shibu MA, Wang WY, Shen SC.
Hsu TW, et al. Among authors: wang th.
Aging (Albany NY). 2023 Jul 11;15(13):6503-6525. doi: 10.18632/aging.204867. Epub 2023 Jul 11.
Aging (Albany NY). 2023.
PMID: 37433225
Free PMC article.
However, not all patients with HCC respond well to sorafenib, and 30% of patients develop resistance to sorafenib after short-term treatment. Galectin-1 modulates cell-cell and cell-matrix interactions and plays a crucial role in HCC progression. ...
However, not all patients with HCC respond well to sorafenib, and 30% of patients develop resistance to sorafenib after short-term tr …