Protein Kinase C Lambda Mediates Acid-Sensing Ion Channel 1a-Dependent Cortical Synaptic Plasticity and Pain Hypersensitivity.
Li HS, Su XY, Song XL, Qi X, Li Y, Wang RQ, Maximyuk O, Krishtal O, Wang T, Fang H, Liao L, Cao H, Zhang YQ, Zhu MX, Liu MG, Xu TL.
Li HS, et al. Among authors: wang rq.
J Neurosci. 2019 Jul 17;39(29):5773-5793. doi: 10.1523/JNEUROSCI.0213-19.2019. Epub 2019 May 17.
J Neurosci. 2019.
PMID: 31101759
Free PMC article.
Here, we provide several lines of evidence to support an important role of cortically located ASIC1a channel in pain hypersensitivity through promoting long-term synaptic potentiation in the ACC. Our results indicate a promising translational potential of targeting ASIC1a …
Here, we provide several lines of evidence to support an important role of cortically located ASIC1a channel in pain hypersensitivity throug …