A Safe, Fibrosis-Mitigating, and Scalable Encapsulation Device Supports Long-Term Function of Insulin-Producing Cells.
Liu W, Flanders JA, Wang LH, Liu Q, Bowers DT, Wang K, Chiu A, Wang X, Ernst AU, Shariati K, Caserto JS, Parker B, Gao D, Plesser MD, Grunnet LG, Rescan C, Pimentel Carletto R, Winkel L, Melero-Martin JM, Ma M.
Liu W, et al. Among authors: wang lh.
Small. 2022 Feb;18(8):e2104899. doi: 10.1002/smll.202104899. Epub 2021 Dec 13.
Small. 2022.
PMID: 34897997
Free PMC article.
Due to its facile mass transfer and low level of fibrotic reactions, the device supports long-term cell engraftment, correcting diabetes in C57BL6/J mice with rat islets for up to 399 days and SCID-beige mice with human SC-beta cells for up to 238 days. ...
Due to its facile mass transfer and low level of fibrotic reactions, the device supports long-term cell engraftment, correcting diabe …